Zobrazeno 1 - 10
of 95
pro vyhledávání: '"Naeun Lee"'
Autor:
Woong-Yang Park, Sehhoon Park, Se-Hoon Lee, Jin Seok Ahn, Myung-Ju Ahn, Jong-Mu Sun, Naeun Lee, Hyun Ae Jung, Hyunsu Kim, Kyoung-Yeon Han, Hyemin Kim
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss 2 (2023)
Background Immune checkpoint inhibitors (ICIs) are an essential treatment for non-small cell lung cancer (NSCLC). Currently, the tumor-related intrinsic factors in response to ICIs have mostly been elucidated in tissue samples. However, tissue immune
Externí odkaz:
https://doaj.org/article/9eb5d73b7dc54f35bec027e772336310
Autor:
Hyoung-oh Jeong, Hayoon Lee, Hyemin Kim, Jinho Jang, Seunghoon Kim, Taejoo Hwang, David Whee-Young Choi, Hong Sook Kim, Naeun Lee, Yoo Mi Lee, Sehhoon Park, Hyun Ae Jung, Jong-Mu Sun, Jin Seok Ahn, Myung-Ju Ahn, Keunchil Park, Semin Lee, Se-Hoon Lee
Publikováno v:
iScience, Vol 25, Iss 11, Pp 105358- (2022)
Summary: Malignant pleural effusion (MPE) is a complication of lung cancer that can be used as an alternative method for tissue sampling because it is generally simple and minimally invasive. Our study evaluated the diagnostic potential of non–smal
Externí odkaz:
https://doaj.org/article/ca078b163bf0462daf569840ae9f0e4f
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Statins, a class of lipid-lowering drugs, are used in drug repositioning for treatment of human cancer. However, the molecular mechanisms underlying statin-induced cancer cell death and autophagy are not clearly defined. In the present study, we show
Externí odkaz:
https://doaj.org/article/941ca74b9acd4b12a50620e281bf8870
Autor:
Jung Yeon Lim, Jung Eun Lee, Han Kyung Kim, Yeon-Joon Park, Jung Ho Jeon, Soon-A. Park, Naeun Lee, Il Hwan Lee, Do Hyun Kim, Seung Ho Yang, Jongman Yoo, Sung Won Kim
Publikováno v:
Cells, Vol 11, Iss 15, p 2285 (2022)
Amyloid-β (Aβ)-peptide production or deposition in the neuropathology of Alzheimer’s disease (AD) was shown to be caused by chronic inflammation that may be induced by infection, but the role of pathogenic-bacteria-related AD-associated Aβ is no
Externí odkaz:
https://doaj.org/article/4bd1cc36d95643e1910685aedf186f1a
Autor:
Seung-Hyun Ro, Julianne Fay, Cesar I. Cyuzuzo, Yura Jang, Naeun Lee, Hyun-Seob Song, Edward N. Harris
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
Proper timely management of various external and internal stresses is critical for metabolic and redox homeostasis in mammals. In particular, dysregulation of mechanistic target of rapamycin complex (mTORC) triggered from metabolic stress and accumul
Externí odkaz:
https://doaj.org/article/47022f999d9c4e3cb47e6f0a3a3230dd
Autor:
Riri Kwon, Bong-Ki Hong, Kang-Gu Lee, Eunbyeol Choi, Laurent Sabbagh, Chul-Soo Cho, Naeun Lee, Wan-Uk Kim
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss 2 (2020)
Background Clinical efficacy of T cell-based cancer immunotherapy is limited by the lack of T cell infiltration in the tumor mass, especially in solid tumors. Our group demonstrated previously that leukocyte-specific protein 1 (LSP1), an intracellula
Externí odkaz:
https://doaj.org/article/4b4c337489c24e3da813172adc83cfe7
Autor:
Riri Kwon, Bong-Ki Hong, Kang-Gu Lee, Eunbyeol Choi, Laurent Sabbagh, Chul-Soo Cho, Naeun Lee, Wan-Uk Kim
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss 2 (2020)
Checkpoint blockade immunotherapy (CBT) can induce long-term clinical benefits in patients with advanced cancer; however, response rates to CBT vary by cancer type. Cancers of the skin, lung, and kidney are largely responsive to CBT, while cancers of
Externí odkaz:
https://doaj.org/article/131d1f397bec4e64b2afd011fb0f1f9b
Autor:
Eun-Jin Han, Hyun Young Kim, Naeun Lee, Nam-Hoon Kim, Seung-Ah Yoo, H. Moo Kwon, Dae-Myung Jue, Yune-Jung Park, Chul-Soo Cho, Tran Quang De, Dae Young Jeong, Hee-Jong Lim, Woo Kyu Park, Ge Hyeong Lee, Heeyeong Cho, Wan-Uk Kim
Publikováno v:
EBioMedicine, Vol 18, Iss C, Pp 261-273 (2017)
Nuclear factor of activated T cells 5 (NFAT5) has been implicated in the pathogenesis of various human diseases, including cancer and arthritis. However, therapeutic agents inhibiting NFAT5 activity are currently unavailable. To discover NFAT5 inhibi
Externí odkaz:
https://doaj.org/article/36a508b094274a66858f7b599d964bb6
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
The nuclear factor of activated T cells (NFAT5), also known as a tonicity-responsive enhancer-binding protein, was originally identified as a key transcription factor involved in maintaining cellular homeostasis against hypertonic and hyperosmotic en
Externí odkaz:
https://doaj.org/article/a81bb9dc4f2949bc9e5e55ec169529d7
Autor:
Jung Hee Koh, Saseong Lee, Hyun-Sook Kim, Kyuheon Lee, Chang Seop Lee, Seung-Ah Yoo, Naeun Lee, Wan-Uk Kim
Publikováno v:
Journal of Clinical Medicine, Vol 9, Iss 11, p 3499 (2020)
Rheumatoid arthritis (RA) disease activity fluctuates over time. The disease activity score 28 (DAS28ESR) is a widely used and validated scoring system for assessing RA activity; however, it requires time and expertise. This study aimed to develop a
Externí odkaz:
https://doaj.org/article/67c51a1f298a4ef6a4cc46ddb065797f