Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Nadya M, Morrow"'
Autor:
Evgenia Fadzeyeva, Cassandra A.A. Locatelli, Natasha A. Trzaskalski, My-Anh Nguyen, Megan E. Capozzi, Branka Vulesevic, Nadya M. Morrow, Peyman Ghorbani, Antonio A. Hanson, Ilka Lorenzen-Schmidt, Mary-Anne Doyle, Richard Seymour, Elodie M. Varin, Morgan D. Fullerton, Jonathan E. Campbell, Erin E. Mulvihill
Publikováno v:
iScience, Vol 26, Iss 5, Pp 106748- (2023)
Summary: Mice systemically lacking dipeptidyl peptidase-4 (DPP4) have improved islet health, glucoregulation, and reduced obesity with high-fat diet (HFD) feeding compared to wild-type mice. Some, but not all, of this improvement can be linked to the
Externí odkaz:
https://doaj.org/article/213537b074c74de6ba1a3b4427a6b586
Autor:
Natasha A. Trzaskalski, Branka Vulesevic, My-Anh Nguyen, Natasha Jeraj, Evgenia Fadzeyeva, Nadya M. Morrow, Cassandra A.A. Locatelli, Nicole Travis, Antonio A. Hanson, Julia R.C. Nunes, Conor O’Dwyer, Jelske N. van der Veen, Ilka Lorenzen-Schmidt, Rick Seymour, Serena M. Pulente, Andrew C. Clément, Angela M. Crawley, René L. Jacobs, Mary-Anne Doyle, Curtis L. Cooper, Kyoung-Han Kim, Morgan D. Fullerton, Erin E. Mulvihill
Publikováno v:
JCI Insight, Vol 8, Iss 2 (2023)
Elevated circulating dipeptidyl peptidase-4 (DPP4) is a biomarker for liver disease, but its involvement in gluconeogenesis and metabolic associated fatty liver disease progression remains unclear. Here, we identified that DPP4 in hepatocytes but not
Externí odkaz:
https://doaj.org/article/40cdcc7f6d5742ecbe16d60323de171c
Autor:
Nadya M. Morrow, Amy C. Burke, Joshua P. Samsoondar, Kyle E. Seigel, Andrew Wang, Dawn E. Telford, Brian G. Sutherland, Conor O'Dwyer, Gregory R. Steinberg, Morgan D. Fullerton, Murray W. Huff
Publikováno v:
Journal of Lipid Research, Vol 61, Iss 3, Pp 387-402 (2020)
Obesity, dyslipidemia, and insulin resistance, the increasingly common metabolic syndrome, are risk factors for CVD and type 2 diabetes that warrant novel therapeutic interventions. The flavonoid nobiletin displays potent lipid-lowering and insulin-s
Externí odkaz:
https://doaj.org/article/4cda3eb4c2104e2fabdf5d55dfd633bf
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Enteroendocrine cells directly integrate signals of nutrient content within the gut lumen with distant hormonal responses and nutrient disposal via the production and secretion of peptides, including glucose-dependent insulinotropic polypeptide (GIP)
Externí odkaz:
https://doaj.org/article/c1e861226b464be39ed7810bb2e08f43
Autor:
Nadya M. Morrow, Erin E. Mulvihill
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 385:1-4
Publikováno v:
Frontiers in Genetics, Vol 11 (2020)
The global prevalence of metabolic disorders, such as obesity, diabetes and fatty liver disease, is dramatically increasing. Both genetic and environmental factors are well-known contributors to the development of these diseases and therefore, the st
Externí odkaz:
https://doaj.org/article/6c7db7e376ca4d33900d1902a8e0ae41
Autor:
Nadya M. Morrow, Natasha A. Trzaskalski, Antonio A. Hanson, Evgenia Fadzeyeva, Dawn E. Telford, Sanjiv S. Chhoker, Brian G. Sutherland, Jane Y. Edwards, Murray W. Huff, Erin E. Mulvihill
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 42:127-144
Objective: Nobiletin is a dietary flavonoid that improves insulin resistance and atherosclerosis in mice with metabolic dysfunction. Dysregulation of intestinal lipoprotein metabolism contributes to atherogenesis. The objective of the study was to de
Autor:
Natasha A, Trzaskalski, Branka, Vulesevic, My-Anh, Nguyen, Natasha, Jeraj, Evgenia, Fadzeyeva, Nadya M, Morrow, Cassandra Aa, Locatelli, Nicole, Travis, Antonio A, Hanson, Julia Rc, Nunes, Conor, O'Dwyer, Jelske N, Van der Veen, Ilka, Lorenzen-Schmidt, Rick, Seymour, Serena M, Pulente, Andrew C, Clément, Angela M, Crawley, René L, Jacobs, Mary-Anne, Doyle, Curtis L, Cooper, Kyoung-Han, Kim, Morgan D, Fullerton, Erin E, Mulvihill
Publikováno v:
JCI insight.
Elevated circulating dipeptidyl-peptidase 4 is a biomarker for liver disease, but its involvement in gluconeogenesis and in metabolic-associated fatty liver disease (MAFLD) progression remains unclear. Here we identified that DPP4 in hepatocytes but
Autor:
Murray W. Huff, Nadya M. Morrow, Conor O’Dwyer, Andrew Wang, Gregory R. Steinberg, Morgan D. Fullerton, Joshua P. Samsoondar, Kyle E. Seigel, Amy C. Burke, Dawn E. Telford, Brian G. Sutherland
Publikováno v:
Journal of Lipid Research, Vol 61, Iss 3, Pp 387-402 (2020)
J Lipid Res
J Lipid Res
Obesity, dyslipidemia, and insulin resistance, the increasingly common metabolic syndrome, are risk factors for CVD and type 2 diabetes that warrant novel therapeutic interventions. The flavonoid nobiletin displays potent lipid-lowering and insulin-s
Autor:
Nadya M. Morrow, Cassandra A.A. Locatelli, Natasha A. Trzaskalski, Chelsea T. Klein, Antonio A. Hanson, Hadeel Alhadi, Ishika Tripathi, Andrew C. Clément, Sara Imran, Ilka Lorenzen-Schmidt, Erin E. Mulvihill
Publikováno v:
Biochimica et biophysica acta. Molecular and cell biology of lipids. 1867(11)
The small intestine is a highly adaptable organ serving as both a barrier to the external environment and a conduit for nutrient absorption. Enterocytes package dietary triglycerides (TG) into chylomicrons for transport into circulation; the remainin