Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Nady Golestaneh"'
Autor:
Shuyan Zhou, Kaan Taskintuna, Jacob Hum, Jasmine Gulati, Stephanie Olaya, Jeremy Steinman, Nady Golestaneh
Publikováno v:
Cell Death and Disease, Vol 15, Iss 6, Pp 1-15 (2024)
Abstract Drusen, the yellow deposits under the retina, are composed of lipids and proteins, and represent a hallmark of age-related macular degeneration (AMD). Lipid droplets are also reported in the retinal pigment epithelium (RPE) from AMD donor ey
Externí odkaz:
https://doaj.org/article/b9c38367b420491db2319b9fde26bdb1
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 18 (2024)
Age-related macular degeneration (AMD) is a major cause of blindness that affects people over 60. While aging is the prominent factor in AMD, studies have reported a higher prevalence of AMD in women compared to age-matched men. Higher levels of the
Externí odkaz:
https://doaj.org/article/1f0f01d4c02740dd903fa538235e86be
Autor:
Shuyan Zhou, Jacob Hum, Kaan Taskintuna, Stephanie Olaya, Jeremy Steinman, Junfeng Ma, Nady Golestaneh
Publikováno v:
Antioxidants, Vol 12, Iss 2, p 385 (2023)
Initially discovered by Makuto Kuro-o in 1997, Klotho is a putative aging-suppressor gene when overexpressed and accelerates aging when deleted in mice. Previously, we showed that α-Klotho regulates retinal pigment epithelium (RPE) functions and pro
Externí odkaz:
https://doaj.org/article/1e6d61fbc64848218c9780e9fe2198d1
Publikováno v:
Frontiers in Genetics, Vol 10 (2019)
Currently, there is much interest in intronic sequence-containing long non-coding RNAs and the role of intronic transcription in regulation of cellular metabolism and fate. Several stable intronic sequence RNAs (sisRNAs) were recently implicated in r
Externí odkaz:
https://doaj.org/article/797f02f0829b4ea598644c0502360203
Autor:
Meng Zhang, Yi Chu, Joseph Mowery, Brandon Konkel, Susana Galli, Alexander C. Theos, Nady Golestaneh
Publikováno v:
Disease Models & Mechanisms, Vol 11, Iss 9 (2018)
Age-related macular degeneration (AMD) is the major cause of blindness in the elderly in developed countries and its prevalence is increasing with the aging population. AMD initially affects the retinal pigment epithelium (RPE) and gradually leads to
Externí odkaz:
https://doaj.org/article/6d060bb8e2d64b36b6825df7921ec440
Autor:
Rency S. Varghese, Nady Golestaneh, Anelia Horvath, Yi Chu, Nisi Jiang, Olga A. Postnikova, Meng Zhang, Amrita K. Cheema
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-14 (2020)
Scientific Reports
Scientific Reports
Age-related macular degeneration is a major cause of vision impairment in the Western world among people of 55 years and older. Recently we have shown that autophagy is dysfunctional in the retinal pigment epithelium (RPE) of the AMD donor eyes (AMD
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d95c9c63d263e5067e330f86ffc3ca04
http://link.springer.com/article/10.1038/s41598-020-59244-4
http://link.springer.com/article/10.1038/s41598-020-59244-4
Publikováno v:
Frontiers in Genetics
Frontiers in Genetics, Vol 10 (2019)
Frontiers in Genetics, Vol 10 (2019)
Currently, there is much interest in intronic sequence-containing long non-coding RNAs and the role of intronic transcription in regulation of cellular metabolism and fate. Several stable intronic sequence RNAs (sisRNAs) were recently implicated in r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::187e8ab459ec0b23de43fb09420cd5f3
https://doi.org/10.3389/fgene.2019.00634
https://doi.org/10.3389/fgene.2019.00634
Publikováno v:
Biomedical Microdevices. 21
The biocompatible and biodegradable polymer poly(glycerol sebacate), or PGS, is a rubber-like material that finds use in several biomedical applications. PGS is often cast into a mold to form desired structures; alternatively, blending PGS with other
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad10f4f9315dba5860299730197069bd
https://doi.org/10.1007/s10544-019-0402-0
https://doi.org/10.1007/s10544-019-0402-0
Autor:
Nady Golestaneh, Meng Zhang, Susana Galli, Brandon Konkel, Joseph Mowery, Yi Chu, Alexander C. Theos
Publikováno v:
Disease Models & Mechanisms
Disease Models & Mechanisms, Vol 11, Iss 9 (2018)
Disease Models & Mechanisms, Vol 11, Iss 9 (2018)
Age-related macular degeneration (AMD) is the major cause of blindness in the elderly in developed countries and its prevalence is increasing with the aging population. AMD initially affects the retinal pigment epithelium (RPE) and gradually leads to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::135ebec698881b30b8b86d561b4aa63b
https://doi.org/10.1242/dmm.032698
https://doi.org/10.1242/dmm.032698
Autor:
Nady Golestaneh, Karolina J. Janczura, Alexander C. Theos, Mia Gunawan, Nishantha Gunawardena, Najiba Murad, Yetrib Hathout, Maria Kokkinaki
Publikováno v:
FEBS Journal. 281:5251-5264
MicroRNA 184 (miR-184) is known to play a key role in neurological development and apoptosis and is highly expressed in mouse brain, mouse corneal epithelium, zebrafish lens and human retinal pigment epithelium (RPE). However, the role of miR-184 in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c77aa08cc2d44f0ee7cda57c968e392
https://doi.org/10.1111/febs.13066
https://doi.org/10.1111/febs.13066