Zobrazeno 1 - 10
of 80
pro vyhledávání: '"Nady El Hajj"'
Autor:
Gowher Ali, Kyung Chul Shin, Nisar Ahmed, Wesal Habbab, Ghaneya Alkhadairi, Aleem Razzaq, Yosra Bejaoui, Nady El Hajj, Borbala Mifsud, Yongsoo Park, Lawrence W. Stanton
Publikováno v:
Cell Death Discovery, Vol 10, Iss 1, Pp 1-10 (2024)
Abstract Rhabdomyosarcoma 2-associated transcript (RMST) long non-coding RNA has previously been shown to cause Kallmann syndrome (KS), a rare genetic disorder characterized by congenital hypogonadotropic hypogonadism (CHH) and olfactory dysfunction.
Externí odkaz:
https://doaj.org/article/81f0e3e030b9477eaf4748cac3a8b2d8
Autor:
Belqes Alsadi, Saleh Musleh, Hamada R. H. Al-Absi, Mahmoud Refaee, Rizwan Qureshi, Nady El Hajj, Tanvir Alam
Publikováno v:
BMC Medical Informatics and Decision Making, Vol 24, Iss 1, Pp 1-15 (2024)
Abstract Background Diabetes is a chronic condition that can result in many long-term physiological, metabolic, and neurological complications. Therefore, early detection of diabetes would help to determine a proper diagnosis and treatment plan. Meth
Externí odkaz:
https://doaj.org/article/5e73473ebd0a4de0ba725ced461831e7
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
The global impact of the SARS-CoV-2 pandemic has been unprecedented, posing a significant public health challenge. Chronological age has been identified as a key determinant for severe outcomes associated with SARS-CoV-2 infection. Epigenetic age acc
Externí odkaz:
https://doaj.org/article/e49f30a965e849a3a30e2103ebafb258
Autor:
Hamada R. H. Al-Absi, Anant Pai, Usman Naeem, Fatma Kassem Mohamed, Saket Arya, Rami Abu Sbeit, Mohammed Bashir, Maha Mohammed El Shafei, Nady El Hajj, Tanvir Alam
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Diabetes mellitus (DM) is a prevalent chronic metabolic disorder linked to increased morbidity and mortality. With a significant portion of cases remaining undiagnosed, particularly in the Middle East North Africa (MENA) region, more accurat
Externí odkaz:
https://doaj.org/article/53e38a63e8de47e2a633911b984b405d
Autor:
Yosra Bejaoui, Fathima Humaira Amanullah, Mohamad Saad, Sara Taleb, Martina Bradic, Andre Megarbane, Ali Ait Hssain, Charbel Abi Khalil, Nady El Hajj
Publikováno v:
Clinical Epigenetics, Vol 15, Iss 1, Pp 1-11 (2023)
Abstract Background Aging has been reported as a major risk factor for severe symptoms and higher mortality rates in COVID-19 patients. Molecular hallmarks such as epigenetic alterations and telomere attenuation reflect the biological process of agin
Externí odkaz:
https://doaj.org/article/b6d4a37ff8e64ffd9795ba60e4c432e0
Autor:
Georges Chehade, Nady El Hajj, Mohamed Aittaleb, Maisa I. Alkailani, Yosra Bejaoui, Asma Mahdi, Arwa A. H. Aldaalis, Michael Verbiest, Julie Lelotte, Nuria Ruiz-Reig, Irene Durá, Christian Raftopoulos, Nicolas Tajeddine, Fadel Tissir
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
BackgroundGlioblastoma is one of the most aggressive primary brain tumors, with a poor outcome despite multimodal treatment. Methylation of the MGMT promoter, which predicts the response to temozolomide, is a well-established prognostic marker for gl
Externí odkaz:
https://doaj.org/article/1369f93b831e4ee098f1f9224cf0cca6
Publikováno v:
npj Digital Medicine, Vol 6, Iss 1, Pp 1-15 (2023)
Abstract The increasing prevalence of type 2 diabetes mellitus (T2DM) and its associated health complications highlight the need to develop predictive models for early diagnosis and intervention. While many artificial intelligence (AI) models for T2D
Externí odkaz:
https://doaj.org/article/605568abb7f241a7b745b680d837c7b0
Publikováno v:
Epigenetics, Vol 18, Iss 1 (2023)
The human ribosomal DNA (rDNA) copy number (CN) has been challenging to analyse, and its sequence has been excluded from reference genomes due to its highly repetitive nature. The 45S rDNA locus encodes essential components of the cell, nevertheless
Externí odkaz:
https://doaj.org/article/26509ae9b42f432f9cd9c7babd23e193
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-16 (2022)
Abstract Healthcare data are inherently multimodal, including electronic health records (EHR), medical images, and multi-omics data. Combining these multimodal data sources contributes to a better understanding of human health and provides optimal pe
Externí odkaz:
https://doaj.org/article/6eaef9911f7b4e5fa3b7c9c54252cc2c
Autor:
Yosra Bejaoui, Sara Alresheq, Sophie Durand, Marie Vilaire-Meunier, Louise Maillebouis, Ayman Al Haj Zen, André Mégarbané, Nady El Hajj
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
BackgroundDown Syndrome (DS) is the most common chromosome anomaly in humans and occurs due to an extra copy of chromosome 21. The malignancy profile in DS is unique, since DS patients have a low risk of developing solid tumors such as breast cancer
Externí odkaz:
https://doaj.org/article/50d1f8dddaac4b9fbd822ef72c563368