Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Nadja Sparding"'
Autor:
Veronika Satrapova, Nadja Sparding, Federica Genovese, Morten Asser Karsdal, Lenka Bartonova, Doubravka Frausova, Eva Honsova, Marek Kollar, Miloslav Suchanek, Helena Koprivova, Romana Rysava, Vladimira Bednarova, Vladimir Tesar, Zdenka Hruskova
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
BackgroundActivity and chronicity of kidney involvement in ANCA-associated vasculitis (AAV) can be currently reliably evaluated only by kidney biopsy. In this study, we measured a panel of serum and urinary biomarkers collected at the time of kidney
Externí odkaz:
https://doaj.org/article/fc1c02196b41492b9c8b4711faf4571b
Autor:
Martin Tepel, Firas F. Alkaff, Daan Kremer, Stephan J. L. Bakker, Olivier Thaunat, Subagini Nagarajah, Qais Saleh, Stefan P. Berger, Jacob van den Born, Nicoline V. Krogstrup, Marie B. Nielsen, Rikke Nørregaard, Bente Jespersen, Nadja Sparding, Federica Genovese, Morten A. Karsdal, Daniel G. K. Rasmussen
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract Delayed graft function after kidney transplantation is common and increases morbidity and health care costs. There is evidence that endotrophin, a specific fragment of pro-collagen type VI, promotes the inflammatory response in kidney diseas
Externí odkaz:
https://doaj.org/article/dc8376e1ebb242f882d7aef601a70e13
Autor:
Nadja Sparding, Michaela Neprasova, Dita Maixnerova, Federica Genovese, Morten Asser Karsdal, Marek Kollar, Helena Koprivova, Zdenka Hruskova, Vladimir Tesar
Publikováno v:
Biomolecules, Vol 13, Iss 7, p 1093 (2023)
Kidney fibrosis is the hallmark of chronic kidney disease (CKD) and is characterized by an imbalanced extracellular matrix (ECM) remodeling. Collagen type III is one of the main ECM components of the interstitial matrix of the kidney. We hypothesized
Externí odkaz:
https://doaj.org/article/e171c07ba959465198a2db809777bd48
Autor:
Nadja Sparding, Federica Genovese, Daniel Guldager Kring Rasmussen, Morten A. Karsdal, Nicoline V. Krogstrup, Marie Bodilsen Nielsen, Mads Hornum, Subagini Nagarajah, Henrik Birn, The CONTEXT Study Group, Bente Jespersen, Martin Tepel, Rikke Nørregaard
Publikováno v:
Biomolecules, Vol 13, Iss 5, p 792 (2023)
Early prediction of kidney graft function may assist clinical management, and for this, reliable non-invasive biomarkers are needed. We evaluated endotrophin (ETP), a novel non-invasive biomarker of collagen type VI formation, as a prognostic marker
Externí odkaz:
https://doaj.org/article/6b7179723dfd45a48c824c320306cac4
Autor:
Nadja Sparding, Hans-Christian Slotved, Gert M Nicolaisen, Steen B Giese, Jón Elmlund, Nina R Steenhard
Publikováno v:
PLoS ONE, Vol 9, Iss 11, p e112876 (2014)
After a potential biological incident the sampling strategy and sample analysis are crucial for the outcome of the investigation and identification. In this study, we have developed a simple sandwich ELISA based on commercial components to quantify B
Externí odkaz:
https://doaj.org/article/01cdc396533546e08a93821919f966b6
Autor:
Nørregaard, Nadja Sparding, Federica Genovese, Daniel Guldager Kring Rasmussen, Morten A. Karsdal, Nicoline V. Krogstrup, Marie Bodilsen Nielsen, Mads Hornum, Subagini Nagarajah, Henrik Birn, The CONTEXT Study Group The CONTEXT Study Group, Bente Jespersen, Martin Tepel, Rikke
Publikováno v:
Biomolecules; Volume 13; Issue 5; Pages: 792
Early prediction of kidney graft function may assist clinical management, and for this, reliable non-invasive biomarkers are needed. We evaluated endotrophin (ETP), a novel non-invasive biomarker of collagen type VI formation, as a prognostic marker
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=multidiscipl::864dc4bc80a4a08b31cd9a2fb291cf5d
Autor:
Nadja Sparding, Daniel Guldager Kring Rasmussen, Federica Genovese, Morten Asser Karsdal, Mads Hornum, Bo Feldt-Rasmussen, Rebecca Packington, Nicholas M. Selby
Publikováno v:
Kidney360
BACKGROUND: AKI involves a rapid decrease in kidney function that may be associated with structural damage. Early markers predicting AKI are emerging, but tools to assess patients’ long-term health risks after AKI are still lacking. Endotrophin (ET
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e18f8f54bffdfb2c0b22b62c054cfb5
https://doi.org/10.34067/kid.0000422021
https://doi.org/10.34067/kid.0000422021
Autor:
Michaela Neprasova, Dita Maixnerova, Nadja Sparding, Federica Genovese, Morten Asser Karsdal, Helena Koprivova, Marek Kollar, Miloslav Suchanek, Zdenka Hruskova, Vladimir Tesar
Publikováno v:
International Journal of Molecular Sciences
Volume 24
Issue 3
Pages: 2064
Volume 24
Issue 3
Pages: 2064
We evaluated biomarkers related to kidney fibrosis for the outcome of patients with IgA nephropathy (IgAN). Clinical parameters (estimated glomerular filtration rate, hypertension, proteinuria) and histological findings were assessed in 134 patients
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1d6c9d25e3ec630940f59b544fb4377
Autor:
Federica Genovese, Dora Balogh, Sandor Koszegi, Attila J. Szabo, Lilla Lenart, Adam Hosszu, Judit Hodrea, Nadja Sparding, Andrea Fekete, László Wagner, Balázs Besztercei
Publikováno v:
Hodrea, J, Balogh, D B, Hosszu, A, Lenart, L, Besztercei, B, Koszegi, S, Sparding, N, Genovese, F, Wagner, L J, Szabo, A J & Fekete, A 2020, ' Reduced O-GlcNAcylation and tubular hypoxia contribute to the antifibrotic effect of SGLT2 inhibitor dapagliflozin in the diabetic kidney ', American journal of physiology. Renal physiology, vol. 318, no. 4, pp. F1017-F1029 . https://doi.org/10.1152/ajprenal.00021.2020
American Journal of Physiology-Renal Physiology
American Journal of Physiology-Renal Physiology
Diabetic kidney disease is a worldwide epidemic, and therapies are incomplete. Clinical data suggest that improved renal outcomes by Na+-glucose cotransporter 2 inhibitor (SGLT2i) are partly beyond their antihyperglycemic effects; however, the mechan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::031baa841634475b1012573f5554f7bf
https://doi.org/10.1152/ajprenal.00021.2020
https://doi.org/10.1152/ajprenal.00021.2020
Autor:
Nadja Sparding, Lenka Bartonova, Zdenka Hruskova, Dita Maixnerova, Daniel Guldager Kring Rasmussen, Doubravka Frausova, Federica Genovese, Michaela Neprasova, Helena Koprivova, Morten A. Karsdal, Vladimir Tesar, Marek Kollar, Eva Honsova, Mads Hornum, Veronika Satrapova
Publikováno v:
Sparding, N, Genovese, F, Rasmussen, D G K, Karsdal, M A, Neprasova, M, Maixnerova, D, Satrapova, V, Frausova, D, Hornum, M, Bartonova, L, Honsova, E, Kollar, M, Koprivova, H, Hruskova, Z & Tesar, V 2022, ' Endotrophin, a collagen type VI-derived matrikine, reflects the degree of renal fibrosis in patients with IgA nephropathy and in patients with ANCA-associated vasculitis ', Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association-European Renal Association, vol. 37, no. 6, pp. 1099-1108 . https://doi.org/10.1093/ndt/gfab163
Background Renal fibrosis is the hallmark of chronic kidney disease (CKD) and is characterized by an imbalanced extracellular matrix remodelling. Endotrophin (ETP) is a signalling molecule released from collagen type VI (COL VI). ETP can be measured
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26cb610f5c7c156eef099dd347ed3a34
https://curis.ku.dk/portal/da/publications/endotrophin-a-collagen-type-viderived-matrikine-reflects-the-degree-of-renal-fibrosis-in-patients-with-iga-nephropathy-and-in-patients-with-ancaassociated-vasculitis(6ffeae9e-6117-4637-a3ff-f2124acda884).html
https://curis.ku.dk/portal/da/publications/endotrophin-a-collagen-type-viderived-matrikine-reflects-the-degree-of-renal-fibrosis-in-patients-with-iga-nephropathy-and-in-patients-with-ancaassociated-vasculitis(6ffeae9e-6117-4637-a3ff-f2124acda884).html
