Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Nadja Schlichenmaier"'
Autor:
Felicitas Piossek, Sascha Beneke, Nadja Schlichenmaier, Goran Mucic, Sabine Drewitz, Daniel R. Dietrich
Publikováno v:
Chemico-biological interactions. 361
Reliable prediction of compound mediated nephrotoxicity in humans is still unsatisfactory irrespective of the recent advancements in in silico, in vitro and in vivo models. Therefore, current in vitro approaches need refinement to better match the hu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b0698fb6b76d9213610cf4c9037a3dd
https://pubmed.ncbi.nlm.nih.gov/35533734
https://pubmed.ncbi.nlm.nih.gov/35533734
Publikováno v:
Archives of toxicology. 93(7)
The kidney is a frequent target for organ-specific toxicity as a result of its primary function in controlling body fluids, for example, via resorption of amino acids, peptides, nutrients, ions, xenobiotics and water from the primary urine as well as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84e03dabe3464ca1d2881273321d914e
https://pubmed.ncbi.nlm.nih.gov/31076804
https://pubmed.ncbi.nlm.nih.gov/31076804
The proximal tubule is the primary site for renal solute reabsorption and secretion and thus a main target for drug-induced toxicity. Current nonclinical methods using 2D cell cultures are unable to fully recapitulate clinical drug responses mainly d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::fd33087a3929e29ef24ba0ab2fc3eb4a
