Výsledky vyhledávání - "Nadja Linzke"

Human Chorionic Gonadotropin as a Central Regulator of Pregnancy Immune Tolerance

Autor: Ana Claudia Zenclussen, Anne Schumacher, Eileen Poloski, Jeanette Witte, Kristina Heinze, Nadja Linzke, Katja Woidacki

Publikováno v: The Journal of Immunology. 190:2650-2658

Normal pregnancy is characterized by an early expansion of regulatory T cells (Tregs), which is known to contribute to fetal tolerance. However, mechanisms and factors behind Treg expansion are not yet defined. Recently, we proposed that the pregnanc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c61623e9ee61d8631cca8f5c3c35a9fa
https://doi.org/10.4049/jimmunol.1202698

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Haem oxygenase-1 dictates intrauterine fetal survival in mice via carbon monoxide

Autor: Hans-Dieter Volk, Stefanie Langwisch, Miguel P. Soares, Maria Laura Zenclussen, Stefan Fest, Sofia Rebelo, Pablo A. Casalis, Tarek El-Mousleh, Nadja Linzke, Ana Claudia Zenclussen

Publikováno v: The Journal of Pathology. 225:293-304

Pregnancy establishment implies the existence of a highly vascularized and transient organ, the placenta, which ensures oxygen supply to the fetus via haemoproteins. Haem metabolism, including its catabolism by haem oxygenase-1 (HO-1), should be of i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3cc24f83f98455d984f7ddf60234624a
https://doi.org/10.1002/path.2946

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Heme oxygenase-1 is critically involved in placentation, spiral artery remodeling, and blood pressure regulation during murine pregnancy

Autor: Maria Laura Zenclussen, Stefan Fest, Anne Schumacher, Nicole Meyer, Pablo A. Casalis, Ana Claudia Zenclussen, Nadja Linzke

Publikováno v: Frontiers in Pharmacology
Frontiers in Pharmacology, Vol 5 (2015)

The onset of pregnancy implies the appearance of a new organ, the placenta. One main function of the placenta is to supply oxygen to the fetus via hemoproteins. In this review, we highlight the importance of the enzyme heme oxygenase-1 (HO-1) for pre

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d769cc4b7383381f2909f71dd2597bae

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Control of Uterine Microenvironment by Foxp3+ Cells Facilitates Embryo Implantation

Autor: Marie Christine Kühnle, Günter J. Hämmerling, Anne Schumacher, Ana Claudia Zenclussen, Ana Teles, Peter Reichardt, Nadja Linzke, Carlos E. Tadokoro, Catharina Thuere

Publikováno v: Frontiers in Immunology, Vol 4 (2013)
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Frontiers in Immunology

Implantation of the fertilized egg into the maternal uterus depends on the fine balance between inflammatory and anti-inflammatory processes. Whilst regulatory T cells (Tregs) are reportedly involved in protection of allogeneic fetuses against reject

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50cd5ff164e871f4db69430f4ab5d875

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Mast cells rescue implantation defects caused by c-kit deficiency

Autor: Katja Woidacki, Gabriel A. Rabinovich, Marcus Maurer, Anne Schumacher, Martin Metz, Federico Jensen, Ana Teles, Milan Popovic, Stefan Fest, F. Poirier, Nadja Linzke, Ana Claudia Zenclussen

Publikováno v: Cell Death Dis
Cell Death Dis, 2013, 4, pp.e462. ⟨10.1038/cddis.2012.214⟩
Cell Death & Disease

International audience; Various physiologically relevant processes are regulated by the interaction of the receptor tyrosine kinase (c-Kit) and its ligand stem cell factor (SCF), with SCF known to be the most important growth factor for mast cells (M

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37f19c8a1e166c206e191f5a44926f7f
https://hal.archives-ouvertes.fr/hal-00813149

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Blockage of heme oxygenase-1 abrogates the protective effect of regulatory T cells on murine pregnancy and promotes the maturation of dendritic cells

Autor: Paul Ojiambo Wafula, Ivonne Wollenberg, Hans-Dieter Volk, Nadja Linzke, Stefanie Langwisch, Stefan Fest, Ana Claudia Zenclussen, Maria Laura Zenclussen, Kristina Heinze, Tarek El-Mousleh, Ana Teles, Anne Schumacher, Pablo A. Casalis

Publikováno v: PLoS ONE, Vol 7, Iss 8, p e42301 (2012)
PLoS ONE

Regulatory T cells (Treg) play an important role in fetal protection. They expand during normal pregnancy and protect fetal antigens from maternal effector cells. Their effect is associated with the up-regulation of tolerance-associated molecules at

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c020fa8b9467189c76fc0521c57776a9
http://europepmc.org/articles/PMC3416808?pdf=render

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Haem oxygenase-1 dictates intrauterine fetal survival in mice via carbon monoxide

Autor: Maria Laura, Zenclussen, Pablo Ariel, Casalis, Tarek, El-Mousleh, Sofia, Rebelo, Stefanie, Langwisch, Nadja, Linzke, Hans-Dieter, Volk, Stefan, Fest, Miguel Parreira, Soares, Ana Claudia, Zenclussen

Publikováno v: The Journal of pathology. 225(2)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::2505a4634af7f727bae1432b24739ac3
https://pubmed.ncbi.nlm.nih.gov/21744344

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Uterine natural killer cells: their modulation by carbon monoxide and their impact on the remodeling of spiral arteries (MUC7P.768)

Autor: Ana Zenclussen, Anne Schumacher, Nadja Linzke

Publikováno v: The Journal of Immunology. 192:197.20-197.20

Pre-eclampsia (PE) and intrauterine growth restriction (IUGR) are linked to impaired remodeling of maternal spiral arteries (SA). We previously introduced Heme Oxygenase-1 (HO-1) as a positive modulator of pregnancy. Its main mediator, carbon monoxid

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b800178161473ea13e0c4d71ffd7a90c
https://doi.org/10.4049/jimmunol.192.supp.197.20

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