Zobrazeno 1 - 9 of 9 pro vyhledávání: '"Nadja Drusenheimer"'
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Akademický článek
Azacitidine, lenalidomide and donor lymphocyte infusions for relapse of myelodysplastic syndrome, acute myeloid leukemia and chronic myelomonocytic leukemia after allogeneic transplant: the Azalena-Trial
Autor: Thomas Schroeder, Matthias Stelljes, Maximilian Christopeit, Eva Esseling, Christoph Scheid, Jan-Henrik Mikesch, Christina Rautenberg, Paul Jäger, Ron-Patrick Cadeddu, Nadja Drusenheimer, Udo Holtick, Stefan Klein, Rudolf Trenschel, Rainer Haas, Ulrich Germing, Nicolaus Kröger, Guido Kobbe
Publikováno v: Haematologica, Vol 108, Iss 11 (2023)
Azacitidine (Aza) combined with donor lymphocyte infusions (DLI) is an established treatment for relapse of myeloid malignancies after allogeneic transplantation. Based on its immunomodulatory and anti-leukemic properties we considered Lenalidomide (
Externí odkaz: https://doaj.org/article/a0b5dba7ca854719927a4d419f0115af
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2
Akademický článek
The Mammalian Orthologs of Drosophila Lgd, CC2D1A and CC2D1B, Function in the Endocytic Pathway, but Their Individual Loss of Function Does Not Affect Notch Signalling.
Autor: Nadja Drusenheimer, Bernhard Migdal, Sandra Jäckel, Lena Tveriakhina, Kristina Scheider, Katharina Schulz, Jieny Gröper, Karl Köhrer, Thomas Klein
Publikováno v: PLoS Genetics, Vol 11, Iss 12, p e1005749 (2015)
CC2D1A and CC2D1B belong to the evolutionary conserved Lgd protein family with members in all multi-cellular animals. Several functions such as centrosomal cleavage, involvement in signalling pathways, immune response and synapse maturation have been
Externí odkaz: https://doaj.org/article/34af95f13b904557bbf3286264b6e091
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4
Overexpression of Lis1 in Different Stages of Spermatogenesis Does Not Result in an Aberrant Phenotype
Autor: Hans-Henning Arnold, Nadja Drusenheimer, B Jung, Andreas Meinhardt, Wolfgang Engel, Karim Nayernia
Publikováno v: Cytogenetic and Genome Research. 134:269-282
Previous studies showed that in the mouse mutant Lis1GT/GT gene trap integration in intron 2 of Lis1 gene leads to male infertility in homozygous Lis1GT/GT mice. We further analyzed this line and could confirm the suggested downregulation of a testis
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b048fa12b0479c3d2d530f4fcb2bbe4a
https://doi.org/10.1159/000329482
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6
Derivation of male germ cells from bone marrow stem cells
Autor: Jae Ho Lee, Karim Nayernia, Jörg Gromoll, Ralf Dressel, Nadja Drusenheimer, Gerald Wulf, Jessica Nolte, Wolfgang Engel
Publikováno v: Laboratory Investigation. 86:654-663
Recent studies have demonstrated that somatic stem cells have a more flexible potential than expected, whether put into tissue or cultured under different conditions. Bone marrow (BM)-derived stem cells can transdifferentiate into multilineage cells,
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29a89103400fd549ff6e2e5b8540f78b
https://doi.org/10.1038/labinvest.3700429
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7
In Vitro-Differentiated Embryonic Stem Cells Give Rise to Male Gametes that Can Generate Offspring Mice
Autor: Thomas Haaf, Andreas Meinhardt, Nadja Drusenheimer, H. W. Michelmann, Kristina Rathsack, Wolfgang Engel, Ingrid Ehrmann, Ulrich Zechner, Gerald Wulf, Jae Ho Lee, Karim Nayernia, Jessica Nolte, David J. Elliott, Arvind Dev, Vera Okpanyi
Publikováno v: Developmental Cell. 11:125-132
SummaryMale gametes originate from a small population of spermatogonial stem cells (SSCs). These cells are believed to divide infinitely and to support spermatogenesis throughout life in the male. Here, we developed a strategy for the establishment o
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ba077142264fe5a6da42cdcd674a6d9
https://doi.org/10.1016/j.devcel.2006.05.010
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8
Multipotent adult germline stem cells and embryonic stem cells have similar microRNA profiles
Autor: Jessica Nolte, Wolfgang Engel, Nadja Drusenheimer, Hiroki Hada, Ulrich Zechner, Kaomei Guan, Athanasios Zovoilis, Karim Nayernia, Gerd Hasenfuss
Publikováno v: Molecular human reproduction. 14(9)
Spermatogonial stem cells (SSCs) isolated from the adult mouse testis and cultured have been shown to respond to culture conditions and become pluripotent, so called multipotent adult germline stem cells (maGSCs). microRNAs (miRNAs) belonging to the
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee19315b26a33040b6aa5ecccecbcf91
https://pubmed.ncbi.nlm.nih.gov/18697907
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9
Putative human male germ cells from bone marrow stem cells
Autor: Nadja, Drusenheimer, Gerald, Wulf, Jessica, Nolte, Jae Ho, Lee, Arvind, Dev, Ralf, Dressel, Jörg, Gromoll, Jörg, Schmidtke, Wolfgang, Engel, Karim, Nayernia
Publikováno v: Society of Reproduction and Fertility supplement. 63
Germ cells must develop along distinct male or female paths to produce the spermatozoa or oocyte required for sexual reproduction. Male germline stem cells maintain spermatogenesis in the postnatal human testis. Here we show that a small population o
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::e5719e23ce204dd37437cde22b89ff65
https://pubmed.ncbi.nlm.nih.gov/17566262
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