Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Nadja Akkad"'
Autor:
Stefan Tenzer, Hayley Crawford, Phillip Pymm, Robert Gifford, Vattipally B. Sreenu, Mirjana Weimershaus, Tulio de Oliveira, Anne Burgevin, Jan Gerstoft, Nadja Akkad, Daniel Lunn, Lars Fugger, John Bell, Hansjörg Schild, Peter van Endert, Astrid K.N. Iversen
Publikováno v:
Cell Reports, Vol 7, Iss 2, Pp 448-463 (2014)
Summary: The recent HIV-1 vaccine failures highlight the need to better understand virus-host interactions. One key question is why CD8+ T cell responses to two HIV-Gag regions are uniquely associated with delayed disease progression only in patients
Externí odkaz:
https://doaj.org/article/70c00bdc9a134a478cc0c679e6af3abb
Publikováno v:
Medical Microbiology and Immunology. 201:463-473
Activation of CD8(+) cytotoxic T cells is crucial for the adaptive immune response against viral infections and the control of malignant transformed cells. Together with activation of costimulatory molecules like CD3 and CD28, CD8(+) T cells need act
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7997663ec18533467342df7177db016c
https://doi.org/10.1007/s00430-012-0266-x
https://doi.org/10.1007/s00430-012-0266-x
Publikováno v:
Journal of Investigative Dermatology. 132(4):1302-1305
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f21eb9428d40db9791cfa3cc5e79e7c8
Autor:
Graham Pawelec, Peter van Endert, Christiane Kellert, Nadja Akkad, Hansjoerg Schild, Barbara Seliger, Stefan Tenzer, Tarish Abbas, Esther Kamphausen
Publikováno v:
Cancer immunology, immunotherapy : CII. 59(8)
Immune surveillance of tumour cells by CD8(+) cytotoxic T cells plays a key role in the establishment and control of an anti-tumour response. This process requires the generation of antigenic peptides, which are largely produced by the proteasome in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::974228cc37662acd10b348cae49c50f6
https://pubmed.ncbi.nlm.nih.gov/20419298
https://pubmed.ncbi.nlm.nih.gov/20419298
Autor:
Anne Burgevin, Søren Buus, Mirjana Weimershaus, P van Endert, Hansjörg Schild, Mikkel Harndahl, Guillaume Stewart-Jones, Jan Gerstoft, Andrew J. McMichael, Kasper Lamberth, Paul Klenerman, L Friis, Nadja Akkad, Stefan Tenzer, Iversen Akn., E Y Jones, E Wee, Chang C-H., Lars Fugger
Publikováno v:
Tenzer, S, Wee, E, Burgevin, A, Stewart-Jones, G, Friis, L, Lamberth, K, Chang, C-H, Harndahl, M, Weimershaus, M, Gerstoft, J, Akkad, N, Klenerman, P, Fugger, L, Jones, E Y, McMichael, A J, Buus, S, Schild, H, van Endert, P & Iversen, A K N 2009, ' Antigen processing influences HIV-specific cytotoxic T lymphocyte immunodominance ', Nature Immunology, vol. 10, no. 6, pp. 636-46 . https://doi.org/10.1038/ni.1728
Nature Immunology; Vol 10
Nature Immunology; Vol 10
Udgivelsesdato: 2009-May-03 Although cytotoxic T lymphocytes (CTLs) in people infected with human immunodeficiency virus type 1 can potentially target multiple virus epitopes, the same few are recognized repeatedly. We show here that CTL immunodomina
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d080244393af2c71d786eaa316801e3c
http://ora.ox.ac.uk/objects/uuid:8a2e9bae-d0d0-47a7-8424-c16c4f410c3a
http://ora.ox.ac.uk/objects/uuid:8a2e9bae-d0d0-47a7-8424-c16c4f410c3a
Autor:
Stefan Tenzer, Björn Peters, Sascha Bulik, Nina Ullrich, Hermann-Georg Holzhütter, Hansjörg Schild, Peter van Endert, Mark M. Schatz, Oliver Carroll, Hans-Georg Rammensee, Alejandra Nacarino Martinez, Nadja Akkad
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 180(5)
Most peptide ligands presented by MHC class I molecules are the product of an intracellular pathway comprising protein breakdown in the cytosol, transport into the endoplasmic reticulum, and successive N-terminal trimming events. The efficiency of ea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae3a23a52798816cb50b49f076e97229
https://pubmed.ncbi.nlm.nih.gov/18768822
https://pubmed.ncbi.nlm.nih.gov/18768822