Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Nadja, Heinrich"'
Publikováno v:
ChemBioChem. 12:2555-2559
Click the switch: By using a photoswitchable click amino acid (PSCaa) a light-induced intramolecular thiol-ene click reaction with a neighboring cysteine under very mild conditions results in an azobenzene bridge. By expanding the genetic code for PS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5585403de976fc188ca6166959834f66
https://doi.org/10.1002/cbic.201100578
https://doi.org/10.1002/cbic.201100578
Autor:
Oliver Kraetke, H. Berger, Michael Bienert, Michael Beyermann, K. Fechner, Nadja Heinrich, W Zhang, Jens Furkert
Publikováno v:
British Journal of Pharmacology. 151:851-859
Background and purpose: Most of the pharmaceuticals target G-protein-coupled receptors (GPCRs) which can generally activate different signalling events. The aim of this study was to achieve functional selectivity of corticotropin-releasing factor rec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4e95acb7f7351dbd3f5fc4655264720d
https://doi.org/10.1038/sj.bjp.0707293
https://doi.org/10.1038/sj.bjp.0707293
Publikováno v:
British Journal of Pharmacology. 149:942-947
Background and purpose: According to the two-domain model for the corticotropin-releasing factor receptor type 1 (CRF1), peptide antagonists bind to the N-terminal domain (N-domain), non-peptide antagonists to the transmembrane region (J-domain), whe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::87c2bad1a16b13731e758e318d7f40ae
https://doi.org/10.1038/sj.bjp.0706926
https://doi.org/10.1038/sj.bjp.0706926
Autor:
Sabine, Abel, Bernhard, Geltinger, Nadja, Heinrich, Dagmar, Michl, Annerose, Klose, Michael, Beyermann, Dirk, Schwarzer
Publikováno v:
Journal of peptide science : an official publication of the European Peptide Society. 20(11)
We have recently developed a soluble mimic of the corticotropin-releasing factor receptor type 1 (CRF1), a membrane-spanning G protein-coupled receptor, which allowed investigations on receptor-ligand interactions. The CRF1 mimic consists of the rece
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f980f644f1c79bcf9fcc5828546fcc00
https://pubmed.ncbi.nlm.nih.gov/25092519
https://pubmed.ncbi.nlm.nih.gov/25092519
Autor:
Mike R. Meyer, Jens Furkert, Annette Sasse, Hartmut Berger, Wolfgang Bönigk, Nadja Heinrich, Michael Beyermann
Publikováno v:
Endocrinology. 139:651-658
The influence of CRF on testosterone production in primary mouse Leydig cell cultures was studied, and the type of CRF receptor (CRF-R) involved in this activity was determined. CRF directly stimulated testosterone production in mouse Leydig cells, b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63c9839fbc4e0cdb5fcbf2ba2854415f
https://doi.org/10.1210/endo.139.2.5754
https://doi.org/10.1210/endo.139.2.5754
Autor:
Nadja Heinrich, Ingo Baeger, Dorothea Lorenz, Klaus Fechner, Hartmut Berger, Nelya N. Samovilova, Erika Albrecht
Publikováno v:
Pharmacology Biochemistry and Behavior. 58:189-194
The highly potent and efficacious mu-opioid agonist fentanyl was SC infused into rats with submaximal analgesic doses (0-1.14 mumol/kg/day) continuously for 8 days, checked by the constant daily urinary recovery of intact drug (0.43 +/- 0.031% of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2a5cd61073cc2ecbfc9985beaac0121
https://doi.org/10.1016/s0091-3057(96)00480-7
https://doi.org/10.1016/s0091-3057(96)00480-7
Autor:
Bernhard Geltinger, Kirill Piotukh, Dirk Schwarzer, Michael Beyermann, Nadja Heinrich, Fabian Gerth, Christian Freund
Publikováno v:
Journal of the American Chemical Society. 133(44)
The ligation of two polypeptides in a chemoselective manner by the bacterial transpeptidase sortase A has become a versatile tool for protein engineering approaches. When sortase-mediated ligation is used for protein semisynthesis, up to four mutatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fb5c42eeb8092ca204e3171a2c625f7
https://pubmed.ncbi.nlm.nih.gov/21978125
https://pubmed.ncbi.nlm.nih.gov/21978125
Autor:
Michael, Beyermann, Nadja, Heinrich, Klaus, Fechner, Jens, Furkert, Wei, Zhang, Oliver, Kraetke, Michael, Bienert, Hartmut, Berger
Publikováno v:
Advances in experimental medicine and biology. 611
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0adf09f80af72b4eca7a3e145295bdc5
https://pubmed.ncbi.nlm.nih.gov/19400304
https://pubmed.ncbi.nlm.nih.gov/19400304
Autor:
Wei Zhang, Nadja Heinrich, Jens Furkert, Klaus Fechner, Oliver Kraetke, Michael Bienert, Hartmut Berger, Michael Beyermann
Publikováno v:
Advances in Experimental Medicine and Biology ISBN: 9780387736563
Introduction Most of the pharmaceuticals today target at G protein-coupled receptors (GPCRs) [1] that transmit extracellular signals into cells. GPCRs are promiscuous, that means a single receptor can activate different signalling events, presumably
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a58e57b6e1d9a80a1cbe2b745346c255
https://doi.org/10.1007/978-0-387-73657-0_237
https://doi.org/10.1007/978-0-387-73657-0_237
Autor:
Ingo Baeger, Hartmut Berger, Uwe Kertscher, Erika Albrecht, Michael Bienert, Nadja Heinrich, Johannes Oehlke, Burkhard Mehlis, Heinz Schäfer
Publikováno v:
Regulatory Peptides. 33:299-311
There are two types of superactive agonists of gonadotropin-releasing hormone (GnRHa-I: ( d -amino acid)6-GnRH and GnRHa-II: ( d -amino acid)6-(desGly)10-GnRH-ethylamide) the high hormonal activity of which is understood to be due to their higher rec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f176ed96a1a8b9f21c6e6b29b70dc45
https://doi.org/10.1016/0167-0115(91)90232-6
https://doi.org/10.1016/0167-0115(91)90232-6