Interaction between methionine synthase isoforms and MMACHC: characterization in cblG-variant, cblG and cblC inherited causes of megaloblastic anaemia

Autor: Mihaela Pupavac, Jean-Marc Alberto, François Feillet, David S. Rosenblatt, Brian Fowler, Natacha Dreumont, Jean-Louis Guéant, Nadir T. Mrabet, Jean-Michel Camadro, Justine Flayac, David Coelho, David Watkins, Céline Chéry, Justine Paoli, Ma'atem B. Fofou-Caillierez

Publikováno v: Human Molecular Genetics
Human Molecular Genetics, Oxford University Press (OUP), 2013, 22 (22), pp.4591-601. ⟨10.1093/hmg/ddt308⟩
HUMAN MOLECULAR GENETICS

International audience; The cblG and cblC disorders of cobalamin (Cbl) metabolism are two inherited causes of megaloblastic anaemia. In cblG, mutations in methionine synthase (MTR) decrease conversion of hydroxocobalamin (HOCbl) to methylcobalamin, w

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa57be78e97c12504e27d92371d3e2da
https://hal.archives-ouvertes.fr/hal-00916700

Natural and chemically induced oligomeric ribonucleases: structural study by immobilized metal ion affinity electrophoresis and their functional relationship

Autor: Maria V. Anissimova, Won-Ok Baek, Valery P. Varlamov, Mookambeswaran A. Vijayalakshmi, Nadir T. Mrabet

Publikováno v: Journal of molecular recognition : JMR. 19(4)

Oligomerization can endow proteins with novel structural and catalytic properties. The native dimer of bovine seminal ribonucleases (BS-RNase) binds, melts and catalyses the hydrolysis of double-stranded ribonucleic acids 30-fold better than its panc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6966d986eb27b898bc6dc3698c53d0c2
https://pubmed.ncbi.nlm.nih.gov/16933205

Residue Accessibility, Hydrogen Bonding, and Molecular Recognition: Metal−Chelate Probing of Active Site Histidines in Chymotrypsins

Autor: Bart Devreese, Jozef Van Beeumen, Jerker Porath, Nadir T. Mrabet, Mookambeswaran A. Vijayalakshmi, Patrick P. Berna

Publikováno v: Biochemistry. 36:16355-16356

Subspecies defining the maturation pathway of bovine chymotrypsinogen to alpha-chymotrypsin have been separated in a single chromatographic run by affinity to iminodiacetic acid-Cu(II) [IDA-Cu(II)] immobilized onto Novarose. A major highlight of the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a5d18be8cd750414460ca373e6896f3
https://doi.org/10.1021/bi975025y