Zobrazeno 1 - 10
of 131
pro vyhledávání: '"Nadir Askenasy"'
Autor:
Svetlana Iskovich, Nitza Goldenberg-Cohen, Tamila Sadikov, Isaac Yaniv, Jerry Stein, Nadir Askenasy M.D., Ph.D.
Publikováno v:
Cell Transplantation, Vol 24 (2015)
We have recently reported that small-sized bone marrow cells (BMCs) isolated by counterflow centrifugal elutriation and depleted of lineage markers (Fr25lin - ) have the capacity to differentiate and contribute to regeneration of injured islets. In t
Externí odkaz:
https://doaj.org/article/1dd9fc6a7ea64645bf4a1e79bcb55347
Publikováno v:
Folia Histochemica et Cytobiologica, Vol 43, Iss 4, Pp 191-195 (2005)
Durable hematopoietic stem cell engraftment requires efficient homing to and seeding in the recipient bone marrow. Dissection of cellular and molecular mechanisms by retrospective analysis of functional engraftment studies imposes severe limitations
Externí odkaz:
https://doaj.org/article/629487b7838a427d9cb66f9aca20d8a4
Autor:
Ayelet Kaminitz, Esma S Yolcu, Enosh M Askenasy, Jerry Stein, Isaac Yaniv, Haval Shirwan, Nadir Askenasy
Publikováno v:
PLoS ONE, Vol 6, Iss 6, p e21630 (2011)
BACKGROUND: Disturbed peripheral negative regulation might contribute to evolution of autoimmune insulitis in type 1 diabetes. This study evaluates the sensitivity of naïve/effector (Teff) and regulatory T cells (Treg) to activation-induced cell dea
Externí odkaz:
https://doaj.org/article/550adadd10774031a12a319ee3e25e7d
Publikováno v:
PLoS ONE, Vol 5, Iss 12, p e15684 (2010)
BACKGROUND: Regulatory T cells (Treg) play a significant role in immune homeostasis and self-tolerance. Excessive sensitivity of isolated Treg to apoptosis has been demonstrated in NOD mice and humans suffering of type 1 diabetes, suggesting a possib
Externí odkaz:
https://doaj.org/article/02c36c75efed4218850fbfc63f54256d
Autor:
Pradeep Shrestha, Ali Turan, Lalit Batra, Ayse Ece Gulen, Zhengda Sun, Helen Tan, Nadir Askenasy, Haval Shirwan, Esma S. Yolcu
Publikováno v:
Blood Advances. 7:2181-2195
Alloreactive T-effector cells (Teffs) are the major culprit of acute graft-versus-host disease (aGVHD) associated with hematopoietic stem cell transplantation. Ex vivo nonspecific depletion of T cells from the donor graft impedes stem cell engraftmen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c3f18588ac549291d06e782725afe036
https://doi.org/10.1182/bloodadvances.2022008495
https://doi.org/10.1182/bloodadvances.2022008495
Autor:
Shifra Ash, Nadir Askenasy
Publikováno v:
Critical Reviews in Oncology/Hematology. 185:103956
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::257ff10771745716e1c0d772c8103180
https://doi.org/10.1016/j.critrevonc.2023.103956
https://doi.org/10.1016/j.critrevonc.2023.103956
Autor:
Kyle B. Woodward, Pradeep Shrestha, Esma S. Yolcu, Hong Zhao, Haval Shirwan, Orlando Grimany-Nuno, Laura Bandura-Morgan, Lalit Batra, Nadir Askenasy, Min Tan
Publikováno v:
Am J Transplant
We have previously shown that pancreatic islets engineered to transiently display a modified form of FasL protein (SA-FasL) on their surface survive indefinitely in allogeneic recipients without a need for chronic immunosuppression. Mechanisms that c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1f0abd1325cd3035d769a3c7d8bb106
https://doi.org/10.1111/ajt.15747
https://doi.org/10.1111/ajt.15747
Autor:
Nadir Askenasy
Publikováno v:
Immunology. 147:377-388
Immune imbalance in autoimmune disorders such as type 1 diabetes may originate from aberrant activities of effector cells or dysfunction of suppressor cells. All possible defective mechanisms have been proposed for diabetes-prone species: (i) quantit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35756b5c4169fb32bff32475c960573a
https://doi.org/10.1111/imm.12581
https://doi.org/10.1111/imm.12581
Autor:
Jean-Jacques Askenasy, Nadir Askenasy
Publikováno v:
Sleep Medicine Clinics. 10:343-350
Adopting prior models of sleep-wake transitions, a flip-flop switch in synchronized neurotransmitter activity is proposed to underlie restless leg syndrome onset. In this model, leg quiescence homeostasis sustained through concerted activities of sev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b44baff267b4de0e46236e6e48a164c1
https://doi.org/10.1016/j.jsmc.2015.05.008
https://doi.org/10.1016/j.jsmc.2015.05.008
Autor:
Nadir Askenasy
Publikováno v:
International Reviews of Immunology. 34:523-537
The prevalent current approach to type 1 diabetes (T1D) is the abrogation of pathogenic potential by immunosuppressive therapy, an intuitive approach aiming to slow down disease progression by the reduction of pathogenic burden. In spite of promising
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec00582cdbf90ac341f9ffacc54e33df
https://doi.org/10.3109/08830185.2015.1010723
https://doi.org/10.3109/08830185.2015.1010723