Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Nadine Zangger"'
Autor:
Caroline Contat, Pierre-Benoit Ancey, Nadine Zangger, Silvia Sabatino, Justine Pascual, Stéphane Escrig, Louise Jensen, Christine Goepfert, Bernard Lanz, Mario Lepore, Rolf Gruetter, Anouk Rossier, Sabina Berezowska, Christina Neppl, Inti Zlobec, Stéphanie Clerc-Rosset, Graham William Knott, Jeffrey C Rathmell, E Dale Abel, Anders Meibom, Etienne Meylan
Publikováno v:
eLife, Vol 9 (2020)
Glucose utilization increases in tumors, a metabolic process that is observed clinically by 18F-fluorodeoxyglucose positron emission tomography (18F-FDG-PET). However, is increased glucose uptake important for tumor cells, and which transporters are
Externí odkaz:
https://doaj.org/article/c3aba89d5d7741e7b31b5d7c0de19941
Autor:
Markus Germann, Nadine Zangger, Marc‐Olivier Sauvain, Christine Sempoux, Amber D Bowler, Pratyaksha Wirapati, Lana E Kandalaft, Mauro Delorenzi, Sabine Tejpar, George Coukos, Freddy Radtke
Publikováno v:
EMBO Molecular Medicine, Vol 12, Iss 1, Pp n/a-n/a (2020)
Abstract High T‐cell infiltration in colorectal cancer (CRC) correlates with a favorable disease outcome and immunotherapy response. This, however, is only observed in a small subset of CRC patients. A better understanding of the factors influencin
Externí odkaz:
https://doaj.org/article/a10c915fbd5647d0990b67d5709c792c
Autor:
Julien Faget, Svenja Groeneveld, Gael Boivin, Martial Sankar, Nadine Zangger, Miguel Garcia, Nicolas Guex, Inti Zlobec, Loïc Steiner, Alessandra Piersigilli, Ioannis Xenarios, Etienne Meylan
Publikováno v:
Cell Reports, Vol 21, Iss 11, Pp 3190-3204 (2017)
Understanding the immune compartment of tumors facilitates the development of revolutionary new therapies. We used a Kras(G12D)-driven mouse model of lung cancer to establish an immune signature and identified a contribution of Gr1+ neutrophils to di
Externí odkaz:
https://doaj.org/article/41248bbbba0546148e82ff48eaa672e0
Autor:
Stefanie Hendrikx, Sanja Coso, Borja Prat-Luri, Laureline Wetterwald, Amélie Sabine, Claudio A. Franco, Sina Nassiri, Nadine Zangger, Holger Gerhardt, Mauro Delorenzi, Tatiana V. Petrova
Publikováno v:
Cell Reports, Vol 26, Iss 5, Pp 1227-1241.e6 (2019)
Summary: Calcineurin/NFAT signaling is active in endothelial cells and is proposed to be an essential component of the tumor angiogenic response. Here, we investigated the role of endothelial calcineurin signaling in vivo in physiological and patholo
Externí odkaz:
https://doaj.org/article/31c17e3c43114c8092a7c7d0cce8e96d
Autor:
Kathryn J Burton, Grégory Pimentel, Nadine Zangger, Nathalie Vionnet, Jocelyne Drai, Philip G McTernan, François P Pralong, Mauro Delorenzi, Guy Vergères
Publikováno v:
PLoS ONE, Vol 13, Iss 2, p e0192947 (2018)
The metabolic health benefits of fermented milks have already been investigated using clinical biomarkers but the development of transcriptomic analytics in blood offers an alternative approach that may help to sensitively characterise such effects.
Externí odkaz:
https://doaj.org/article/c6049b55f1d84df6b2ab77162e8948f7
Autor:
Simone Ragusa, Jianpin Cheng, Konstantin I. Ivanov, Nadine Zangger, Fatih Ceteci, Jeremiah Bernier-Latmani, Stavros Milatos, Jean-Marc Joseph, Stephane Tercier, Hanifa Bouzourene, Fredrik T. Bosman, Igor Letovanec, Giancarlo Marra, Michel Gonzalez, Patrizia Cammareri, Owen J. Sansom, Mauro Delorenzi, Tatiana V. Petrova
Publikováno v:
Cell Reports, Vol 8, Iss 6, Pp 1957-1973 (2014)
The Wnt pathway is abnormally activated in the majority of colorectal cancers, and significant knowledge has been gained in understanding its role in tumor initiation. However, the mechanisms of metastatic outgrowth in colorectal cancer remain a majo
Externí odkaz:
https://doaj.org/article/3452875f09dd4a759050b3ac0a59ac43
Autor:
Pejman Mohammadi, Sébastien Desfarges, István Bartha, Beda Joos, Nadine Zangger, Miguel Muñoz, Huldrych F Günthard, Niko Beerenwinkel, Amalio Telenti, Angela Ciuffi
Publikováno v:
PLoS Pathogens, Vol 11, Iss 6, p e1005006 (2015)
[This corrects the article DOI: 10.1371/journal.ppat.1003161.].
Externí odkaz:
https://doaj.org/article/bbac5a1ad4e44fca85de338ae859f5fc
Autor:
Pejman Mohammadi, Sébastien Desfarges, István Bartha, Beda Joos, Nadine Zangger, Miguel Muñoz, Huldrych F Günthard, Niko Beerenwinkel, Amalio Telenti, Angela Ciuffi
Publikováno v:
PLoS Pathogens, Vol 9, Iss 1, p e1003161 (2013)
HIV-1 infects CD4+ T cells and completes its replication cycle in approximately 24 hours. We employed repeated measurements in a standardized cell system and rigorous mathematical modeling to characterize the emergence of the viral replication interm
Externí odkaz:
https://doaj.org/article/3c2a7340926c4c58824cb6570af54114
Autor:
Nuria Izquierdo-Useros, Maier Lorizate, Maria C Puertas, Maria T Rodriguez-Plata, Nadine Zangger, Elina Erikson, Maria Pino, Itziar Erkizia, Bärbel Glass, Bonaventura Clotet, Oliver T Keppler, Amalio Telenti, Hans-Georg Kräusslich, Javier Martinez-Picado
Publikováno v:
PLoS Biology, Vol 10, Iss 12, p e1001448 (2012)
Dendritic cells (DCs) are essential antigen-presenting cells for the induction of immunity against pathogens. However, HIV-1 spread is strongly enhanced in clusters of DCs and CD4(+) T cells. Uninfected DCs capture HIV-1 and mediate viral transfer to
Externí odkaz:
https://doaj.org/article/5444d13e2640426a8cc06d28d82dad0e
Autor:
Anna C Groner, Sylvain Meylan, Angela Ciuffi, Nadine Zangger, Giovanna Ambrosini, Nicolas Dénervaud, Philipp Bucher, Didier Trono
Publikováno v:
PLoS Genetics, Vol 6, Iss 3, p e1000869 (2010)
Krüppel-associated box domain-zinc finger proteins (KRAB-ZFPs) are tetrapod-specific transcriptional repressors encoded in the hundreds by the human genome. In order to explore their as yet ill-defined impact on gene expression, we developed an ecto
Externí odkaz:
https://doaj.org/article/dcfb346df7f746f385b05e131a030c79