Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Nadine Szumilas"'
Autor:
Nadine Szumilas, Odilia B. J. Corneth, Christian H. K. Lehmann, Heike Schmitt, Svenia Cunz, Jolie G. Cullen, Talyn Chu, Anita Marosan, Attila Mócsai, Vladimir Benes, Dietmar Zehn, Diana Dudziak, Rudi W. Hendriks, Lars Nitschke
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Siglec-H is a DAP12-associated receptor on plasmacytoid dendritic cells (pDCs) and microglia. Siglec-H inhibits TLR9-induced IFN-α production by pDCs. Previously, it was found that Siglec-H-deficient mice develop a lupus-like severe autoimmune disea
Externí odkaz:
https://doaj.org/article/c505db08fdab443ead7dba66ecb91da3
Autor:
Lars Nitschke, Nadine Szumilas, Daniel Radtke, Sonja M. Lacher, Elisabeth Zinser, Jochen A. Ackermann, Lena Sandrock
Publikováno v:
The Journal of Immunology. 196:2995-3005
The small adaptor protein growth factor receptor–bound protein 2 (Grb2) modulates and integrates signals from receptors on cellular surfaces in inner signaling pathways. In murine T cells, Grb2 is crucial for amplification of TCR signaling. T cell