Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Nadine Sperb"'
Autor:
Miltiadis Tsesmelis, Ulrike F. G. Büttner, Melanie Gerstenlauer, Uta Manfras, Konstantinos Tsesmelis, Ziwei Du, Nadine Sperb, Stephanie Ellen Weissinger, Peter Möller, Thomas F. E. Barth, Harald J. Maier, Lap Kwan Chan, Thomas Wirth
Publikováno v:
Molecular Cancer, Vol 23, Iss 1, Pp 1-20 (2024)
Abstract Background Pancreatic ductal adenocarcinoma (PDAC) is marked by a dismal survival rate, lacking effective therapeutics due to its aggressive growth, late-stage diagnosis, and chemotherapy resistance. Despite debates on NF-κB targeting for P
Externí odkaz:
https://doaj.org/article/d60de3829ea54fce943d4b1ee9fe0c20
Autor:
Sarah Grasedieck, Ariene Cabantog, Liam MacPhee, Junbum Im, Christoph Ruess, Burcu Demir, Nadine Sperb, Frank G. Rücker, Konstanze Döhner, Tobias Herold, Jonathan R. Pollack, Lars Bullinger, Arefeh Rouhi, Florian Kuchenbauer
Publikováno v:
Haematologica, Vol 107, Iss 8 (2021)
Aberrant expression of Ecotropic Viral Integration Site 1 (EVI1) is a hallmark of acute myeloid leukemia (AML) with inv(3) or t(3;3), which is a disease subtype with especially poor outcome. In studying transcriptomes from AML patients with chromosom
Externí odkaz:
https://doaj.org/article/4a9816313b7b445f9cb7831766ece0b2
Autor:
Liam MacPhee, Florian Kuchenbauer, Sarah Grasedieck, Lars Bullinger, Ariene Cabantog, Junbum Im, Konstanze Döhner, Tobias Herold, Jonathan R. Pollack, Nadine Sperb, Christoph Ruess, Burcu Demir, Arefeh Rouhi, Frank G. Rücker
Publikováno v:
Haematologica. 107:1758-1772
Aberrant expression of Ecotropic Viral Integration Site 1 (EVI1) is a hallmark of acute myeloid leukemia (AML) with inv(3) or t(3;3), which is a disease subtype with especially poor outcome. In studying transcriptomes from AML patients with chromosom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::baa3547391b696cd5523edb03339a5df
https://doi.org/10.3324/haematol.2021.276048
https://doi.org/10.3324/haematol.2021.276048
Autor:
Florian Kuchenbauer, Meena Kanduri, Lars Palmqvist, Reinhild Rösler, Christoph Ruess, Nadine Sperb, Christina Miller, Hartmut Döhner, Nicole Pochert, Erik Delsing Malmberg, Martin Hirst, Anna Staffas, Pradeep Kumar Kopparapu, Alireza Heravi-Moussavi, Alireza Lorzadeh, Ping Xiang, R. Keith Humphries, Sarah Grasedieck, Erik Larsson, Sebastian Wiese, Arghavan Ashouri, Liam MacPhee, Konstanze Döhner, Leo Escano, Linda Fogelstrand, Sebastian Iben, Edith Schneider, Kathrin Krowiorz, Arefeh Rouhi
Publikováno v:
Leukemia. 34:1253-1265
MicroRNAs (miRNAs) are commonly deregulated in acute myeloid leukemia (AML), affecting critical genes not only through direct targeting, but also through modulation of downstream effectors. Homeobox (Hox) genes balance self-renewal, proliferation, ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d076b36c05970c320be90295fd04c8e0
https://doi.org/10.1038/s41375-019-0651-1
https://doi.org/10.1038/s41375-019-0651-1
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 21, Iss 5486, p 5486 (2020)
International Journal of Molecular Sciences, Vol 21, Iss 5486, p 5486 (2020)
Pancreatic ductal adenocarcinoma (PDAC) remains a lethal cancer. The poor prognosis calls for a more detailed understanding of disease biology in order to pave the way for the development of effective therapies. Typically, the pancreatic tumor is com
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a06fa9cea6b4265fab19dade6259f345
https://doi.org/10.3390/ijms21155486
https://doi.org/10.3390/ijms21155486
Autor:
Florian Kuchenbauer, Linda Fogelstrand, Sebastian Wiese, Tobias Maetzig, Hartmut Döhner, Nadine Sperb, Lars Palmqvist, Enrico Calzia, Nicole Pochert, Christoph Rueß, Sarah Grasedieck, Laleh Arabanian, Pegah Johansson, Edith Schneider, Kathrin Krowiorz, Erik Delsing Malmberg, Reinhild Rösler, Arefeh Rouhi
Publikováno v:
Blood. 132:3924-3924
The miR-106a-363 cluster, encoding six miRNAs (miR-106a, miR-18b, miR-20b, miR-19b, miR-92a and miR-363), is a paralogue of the oncogenic miR-17-92a polycistron and its role in leukemia is at present largely unknown. We aimed to investigate the putat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0f40b367f3b921b156e370d5281b6f37
https://doi.org/10.1182/blood-2018-99-116035
https://doi.org/10.1182/blood-2018-99-116035