Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Nadine S. Taylor"'
Publikováno v:
Metabolites, Vol 8, Iss 3, p 42 (2018)
Chemical risk assessment remains entrenched in chronic toxicity tests that set safety thresholds based on animal pathology or fitness. Chronic tests are resource expensive and lack mechanistic insight. Discovering a chemical’s mode-of-action can in
Externí odkaz:
https://doaj.org/article/d31d6b9ffb8740cdbe7d14ee471b78ba
Publikováno v:
Metabolites, Vol 7, Iss 1, p 11 (2017)
Recent technological advancement has enabled the emergence of lipidomics as an important tool for assessing molecular stress, one which has yet to be assessed fully as an approach in an environmental toxicological context. Here we have applied a high
Externí odkaz:
https://doaj.org/article/333f6a0a9c784bb3817fa75da3abf91c
Analysis and management of herbicidal mixtures in a high‐intensity agricultural landscape in Belgium
Publikováno v:
Integrated Environmental Assessment and Management.
Waterbodies located in anthropogenically influenced environments, such as agricultural landscapes, may be exposed to different chemicals simultaneously, or sequentially. Yet, current environmental risk assessments focus on single active substances fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bad28c8d6744994f2e571f651d2d2fd9
https://doi.org/10.1002/ieam.4727
https://doi.org/10.1002/ieam.4727
Autor:
Erica K. Brockmeier, Danilo Basili, John Herbert, Cecilie Rendal, Leigh Boakes, Arturas Grauslys, Nadine S. Taylor, Emma Butler Danby, Steve Gutsell, Rakesh Kanda, Mark Cronin, Jeff Barclay, Philipp Antczak, Mark R. Viant, Geoff Hodges, Francesco Falciani
Publikováno v:
The Science of the total environment. 849
Supplementary data related to this article: Supplementary material, available at https://ars.els-cdn.com/content/image/1-s2.0-S0048969722047647-mmc1.docx (Word document35, 5KB)); Supplementary Data 1. These are the chemicals along with their properti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02f88b633ef2992515f8769b1ba7f58d
https://pubmed.ncbi.nlm.nih.gov/35908689
https://pubmed.ncbi.nlm.nih.gov/35908689
Autor:
John M. Gunn, James C. McGeer, Norman D. Yan, Jennifer A. Kirwan, Nadine S. Taylor, Mark R. Viant
Publikováno v:
Environmental Toxicology and Chemistry. 35:635-644
Reductions in atmospheric emissions from the metal smelters in Sudbury, Canada, produced major improvements in acid and metal contamination of local lakes and indirectly increased dissolved organic carbon (DOC) concentrations. Metal toxicity, however
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e845a15e32a58b28cc3ff2880791d4c8
https://doi.org/10.1002/etc.3206
https://doi.org/10.1002/etc.3206
Publikováno v:
Metabolites, Vol 8, Iss 3, p 42 (2018)
Metabolites
Volume 8
Issue 3
Metabolites
Volume 8
Issue 3
Chemical risk assessment remains entrenched in chronic toxicity tests that set safety thresholds based on animal pathology or fitness. Chronic tests are resource expensive and lack mechanistic insight. Discovering a chemical&rsquo
s mode-of-acti
s mode-of-acti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7ea7d7297152f0a947a8a9151135652
http://www.mdpi.com/2218-1989/8/3/42
http://www.mdpi.com/2218-1989/8/3/42
Autor:
Erica K. Brockmeier, Emma Butler, Geoff Hodges, Steve Gutsell, John K. Colbourne, Cecilie Rendal, Nadine S. Taylor
Publikováno v:
A Systems Biology Approach to Advancing Adverse Outcome Pathways for Risk Assessment ISBN: 9783319660820
In this chapter, we present the use of invertebrate model species in the development of adverse outcome pathways (AOPs), its challenges, and the current state of invertebrate toxicity studies. Invertebrates can contribute significantly towards the de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::945ef96e077e779ac47059f37c2166c6
https://doi.org/10.1007/978-3-319-66084-4_5
https://doi.org/10.1007/978-3-319-66084-4_5
Publikováno v:
Metabolites
Metabolites; Volume 7; Issue 1; Pages: 11
Metabolites, Vol 7, Iss 1, p 11 (2017)
Metabolites; Volume 7; Issue 1; Pages: 11
Metabolites, Vol 7, Iss 1, p 11 (2017)
Recent technological advancement has enabled the emergence of lipidomics as an important tool for assessing molecular stress, one which has yet to be assessed fully as an approach in an environmental toxicological context. Here we have applied a high
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d0873d9a16d6e051626adce8212af55
http://europepmc.org/articles/PMC5372214
http://europepmc.org/articles/PMC5372214
Autor:
Sarah Chan, Joshua M. Hicks, Helen C. Poynton, Alexandre Loguinov, Mark R. Viant, Kimberly L. Colson, Leona D. Scanlan, Chris D. Vulpe, Nadine S. Taylor, Candace Clark
Publikováno v:
Environmental Science & Technology. 45:3710-3717
Omic technologies offer unprecedented opportunities to better understand mode(s)-of-toxicity and downstream secondary effects by providing a holistic view of the molecular changes underlying physiological disruption. Crustacean hemolymph represents a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::421f9a7f3b6d60048406aa9d6950e875
https://doi.org/10.1021/es1037222
https://doi.org/10.1021/es1037222
Publikováno v:
Toxicological Sciences. 118:307-317
Currently, there is widespread interest in exploiting "omics" approaches to screen the toxicity of chemicals, potentially enabling their rapid categorization into classes of defined mode of action (MOA). Direct infusion Fourier transform ion cyclotro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c8baa8cb0bf327bc655622ef89ac4c3
https://doi.org/10.1093/toxsci/kfq247
https://doi.org/10.1093/toxsci/kfq247