Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Nadine Rohwer"'
Autor:
Chaoxuan Wang, Anne Kaufmann, Nadja Kampschulte, Ulf Elbelt, Ursula Kassner, Elisabeth Steinhagen-Thiessen, Anne Pietzner, Christoph Schmöcker, Dev Datta, Tiziana Sanpietro, Nils Helge Schebb, Karsten-H. Weylandt, Nadine Rohwer
Publikováno v:
Atherosclerosis Plus, Vol 55, Iss , Pp 55-62 (2024)
Background and aims: Previous studies have shown that lipoprotein apheresis can modify the plasma lipidome and pro-inflammatory and pro-thrombotic lipid mediators. This has not been examined for treatment with protein convertase subtilisin/kexin type
Externí odkaz:
https://doaj.org/article/f317981a5ce3410fab89f29231cbc448
Autor:
Can G. Leineweber, Miriam Rabehl, Anne Pietzner, Nadine Rohwer, Michael Rothe, Maciej Pech, Bruno Sangro, Rohini Sharma, Chris Verslype, Bristi Basu, Christian Sengel, Jens Ricke, Nils Helge Schebb, Karsten-H. Weylandt, Julia Benckert
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2024)
Externí odkaz:
https://doaj.org/article/b9260c68d14a43f7a3628074ecc8465c
Autor:
Yanan Xiao, Anne Pietzner, Nadine Rohwer, Adelheid Jung, Michael Rothe, Karsten H. Weylandt, Ulf Elbelt
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
ObjectiveDyslipidemia, in particular elevated triglycerides (TGs) contribute to increased cardiovascular risk in type 2 diabetes mellitus (T2DM). In this pilot study we aimed to assess how increased TGs affect hepatic fat as well as polyunsaturated f
Externí odkaz:
https://doaj.org/article/ed0233e777b64162b81114d4fe8d3620
Autor:
Nadine Rohwer, Julia Jelleschitz, Annika Höhn, Daniela Weber, Anja A. Kühl, Chaoxuan Wang, Rei-Ichi Ohno, Nadja Kampschulte, Anne Pietzner, Nils Helge Schebb, Karsten-H. Weylandt, Tilman Grune
Publikováno v:
Redox Biology, Vol 64, Iss , Pp 102803- (2023)
Inflammatory bowel disease (IBD) is an immune-mediated gut dysfunction, which might also be associated with an inflammatory phenotype in the liver. It is known that the nutritional intake of omega-3 polyunsaturated fatty acids (n-3 PUFA) is inversely
Externí odkaz:
https://doaj.org/article/c6e9aad1d18948899935e0e4f6318c2a
Autor:
Can G. Leineweber, Miriam Rabehl, Anne Pietzner, Nadine Rohwer, Michael Rothe, Maciej Pech, Bruno Sangro, Rohini Sharma, Chris Verslype, Bristi Basu, Christian Sengel, Jens Ricke, Nils Helge Schebb, Karsten-H. Weylandt, Julia Benckert
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Hepatocellular carcinoma (HCC) is a leading cause of cancer death, and medical treatment options are limited. The multikinase inhibitor sorafenib was the first approved drug widely used for systemic therapy in advanced HCC. Sorafenib might affect pol
Externí odkaz:
https://doaj.org/article/630cda002caf4e259f38d949754a2b84
Autor:
Nils Helge Schebb, Hartmut Kühn, Astrid S. Kahnt, Katharina M. Rund, Valerie B. O’Donnell, Nicolas Flamand, Marc Peters-Golden, Per-Johan Jakobsson, Karsten H. Weylandt, Nadine Rohwer, Robert C. Murphy, Gerd Geisslinger, Garret A. FitzGerald, Julien Hanson, Claes Dahlgren, Mohamad Wessam Alnouri, Stefan Offermanns, Dieter Steinhilber
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Formation of specialized pro-resolving lipid mediators (SPMs) such as lipoxins or resolvins usually involves arachidonic acid 5-lipoxygenase (5-LO, ALOX5) and different types of arachidonic acid 12- and 15-lipoxygenating paralogues (15-LO1, ALOX15; 1
Externí odkaz:
https://doaj.org/article/4d550b6401b044cfacb01d9180ee3c13
Autor:
Nadine Rohwer, Anja A. Kühl, Annika I. Ostermann, Nicole Marie Hartung, Nils Helge Schebb, Dieter Zopf, Fiona M. McDonald, Karsten‐H. Weylandt
Publikováno v:
Cancer Medicine, Vol 9, Iss 7, Pp 2535-2550 (2020)
Abstract Although early detection and treatment of colorectal cancer (CRC) have improved, it remains a significant health‐care problem with high morbidity and mortality. Data indicate that long‐term intake of low‐dose aspirin reduces the risk o
Externí odkaz:
https://doaj.org/article/f2e1ed8c4eb54e558fb7780edb8c9158
Autor:
Heike Gottschall, Christoph Schmöcker, Dirk Hartmann, Nadine Rohwer, Katharina Rund, Laura Kutzner, Fabian Nolte, Annika I. Ostermann, Nils Helge Schebb, Karsten H. Weylandt
Publikováno v:
Journal of Lipid Research, Vol 59, Iss 5, Pp 864-871 (2018)
Eicosanoids, including prostaglandins (PGs) and thromboxanes, are broadly bioactive lipid mediators and increase colon tumorigenesis possibly through chronic inflammatory mechanisms. Epidemiological and experimental data suggest that acetylsalicylic
Externí odkaz:
https://doaj.org/article/68d5fe5824b944c1a73fd9fb68e45169
Autor:
Eugenia Marbach-Breitrück, Nadine Rohwer, Carmen Infante-Duarte, Silvina Romero-Suarez, Dominika Labuz, Halina Machelska, Laura Kutzner, Nils Helge Schebb, Michael Rothe, Pallu Reddanna, Karsten H. Weylandt, Lothar H. Wieler, Dagmar Heydeck, Hartmut Kuhn
Publikováno v:
Metabolites, Vol 11, Iss 10, p 698 (2021)
Arachidonic acid 5-lipoxygenase (ALOX5) is the key enzyme in the biosynthesis of pro-inflammatory leukotrienes. We recently created knock-in mice (Alox5-KI) which express an arachidonic acid 15-lipoxygenating Alox5 mutant instead of the 5-lipoxygenat
Externí odkaz:
https://doaj.org/article/b38f815a74e244eb91e567f76b5d8645
Autor:
Annika I Ostermann, Patrick Waindok, Moritz J Schmidt, Cheng-Ying Chiu, Christopher Smyl, Nadine Rohwer, Karsten-H Weylandt, Nils Helge Schebb
Publikováno v:
PLoS ONE, Vol 12, Iss 9, p e0184470 (2017)
Dietary intervention and genetic fat-1 mice are two models for the investigation of effects associated with omega-3 polyunsaturated fatty acids (n3-PUFA). In order to assess their power to modulate the fatty acid and oxylipin pattern, we thoroughly c
Externí odkaz:
https://doaj.org/article/a786b4508bc44737971b7f105d8b91c9