Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Nadine Pollak"'
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Publikováno v:
Journal of Cell Science. Dec2021, Vol. 134 Issue 24, p1-2. 2p.
Publikováno v:
PLoS Computational Biology, Vol 16, Iss 6, p e1007812 (2020)
Apoptotic cell death can be initiated through the extrinsic and intrinsic signaling pathways. While cell cycle progression promotes the responsiveness to intrinsic apoptosis induced by genotoxic stress or spindle poisons, this has not yet been studie
Externí odkaz:
https://doaj.org/article/df01bb7e1d354c4297daaf5098cedcc8
Publikováno v:
PLoS ONE, Vol 13, Iss 6, p e0198203 (2018)
Dysregulation of the mitochondrial signaling pathway of apoptosis induction represents a major hurdle in tumor therapy. The objective of the presented work was to investigate the role of the intrinsic (mitochondrial) apoptotic pathway in the non-smal
Externí odkaz:
https://doaj.org/article/9e232127ea1d4ef3932132940bc1d1b5
Cell cycle progression and transmitotic apoptosis resistance promote escape from extrinsic apoptosis
Autor:
Peter Scheurich, Frank Allgöwer, Daniela Stöhr, Markus Rehm, Isabel Heinrich, Karsten Kuritz, Nadine Pollak, Aline Lindner, Lorena Decker, Jacques S Fritze, Jannis Stadager, Dirke Imig, Stephan A. Eisler
Publikováno v:
Journal of Cell Science. 134
Extrinsic apoptosis relies on TNF-family receptor activation by immune cells or receptor-activating drugs. Here, we monitored cell cycle progression at a resolution of minutes to relate apoptosis kinetics and cell-to-cell heterogeneities in death dec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d58a0d8bb5223055bc6ed248d9a2252
https://doi.org/10.1242/jcs.258966
https://doi.org/10.1242/jcs.258966
Publikováno v:
IFAC-PapersOnLine. 52:207-212
The endogenous ligand TRAIL induces cell death and constitutes a promising molecule for cancer therapies. However, reasons for TRAIL-insensitivity of various tumor-based cancer cell lines remain unclear. In this paper, we introduce a complex individu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9f9c86e489d2b21a56fda944eff7817e
https://doi.org/10.1016/j.ifacol.2019.12.259
https://doi.org/10.1016/j.ifacol.2019.12.259
Autor:
Nadine Pollak, Jacques S Fritze, Peter Scheurich, Karsten Kuritz, Heinrich I, Daniela Stöhr, Stadager J, Frank Allgöwer, Morrison (Rehm) M, Stephan A. Eisler, Lindner A, Dirke Imig
Extrinsic apoptosis relies on TNF-family receptor activation by immune cells or receptor-activating biologics. Here, we monitored cell cycle progression at minutes resolution to relate apoptosis kinetics and cell-to-cell heterogeneities in death deci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c10c31887ebdd075fce8b628a8c953b7
https://doi.org/10.1101/2021.02.26.433034
https://doi.org/10.1101/2021.02.26.433034
Autor:
Kai Cao, Peter Scheurich, Roland E. Kontermann, Tobias B. Beigl, Thomas E. Mürdter, Cathrin Hagenlocher, Alexandra Mack, Daniela Simone Maichl, Stephen W.G. Tait, Daniela Stöhr, Markus Rehm, Beate Budai, Jens O Schmid, Gavin Fullstone, Nadine Pollak
Publikováno v:
Cell Death and Differentiation
The influence of 3D microenvironments on apoptosis susceptibility remains poorly understood. Here, we studied the susceptibility of cancer cell spheroids, grown to the size of micrometastases, to tumor necrosis factor-related apoptosis-inducing ligan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4746167a42442d4aa67874014f1dcaf8
https://eprints.gla.ac.uk/219472/1/219472.pdf
https://eprints.gla.ac.uk/219472/1/219472.pdf
Publikováno v:
IFAC-PapersOnLine. 51:90-93
Drug-induced cell death on the one hand, and dynamics of the cell cycle on the other hand, represent two well-investigated biological principles. As the cell death machinery is highly regulated and depends on a large number of signaling proteins, a c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3bd23fc305bf367f6b32da76dba56489
https://doi.org/10.1016/j.ifacol.2018.09.028
https://doi.org/10.1016/j.ifacol.2018.09.028
Publikováno v:
Journal of Theoretical Biology. 414:91-102
Cyclic processes, in particular the cell cycle, are of great importance in cell biology. Continued improvement in cell population analysis methods like fluorescence microscopy, flow cytometry, CyTOF or single-cell omics made mathematical methods base
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7fcd361ed29ec3659d9dff09a91f7fb2
https://doi.org/10.1016/j.jtbi.2016.11.024
https://doi.org/10.1016/j.jtbi.2016.11.024