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pro vyhledávání: '"Nadine Narboux"'
Autor:
Dennis Bigg, Simon P. Newman, Chloe Stengel, Sonia Bernetiere, Raphael Dellile, Mark Carlson, José Camara, Eric Ferrandis, Mélissa Le Moing, Nadine Narboux, Vincent Hesry, Delphine Morlais, Olivier Dutruel, Dominique Pons, Pierrick Auvray, Anne-Marie Liberatore, Philip G. Kasprzyk, Hélène Coulomb, Ann Savola Nelson, Béatrice Foll, Gregoire Prevost
Publikováno v:
Molecular Cancer Therapeutics. 7:2426-2434
Tubulin is a validated target for antitumor drugs. However, the effectiveness of these microtubule-interacting agents is limited by the fact that they are substrates for drug efflux pumps (P-glycoprotein) and/or by the acquisition of point mutations