Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Nadine Michel"'
Autor:
Nadine Michel, Heather M. Raimer Young, Naomi D. Atkin, Umar Arshad, Reem Al-Humadi, Sandeep Singh, Arkadi Manukyan, Lana Gore, Ian E. Burbulis, Yuh-Hwa Wang, Michael J. McConnell
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-14 (2022)
Abstract Neurons are overproduced during cerebral cortical development. Neural progenitor cells (NPCs) divide rapidly and incur frequent DNA double-strand breaks (DSBs) throughout cortical neurogenesis. Although half of the neurons born during neurod
Externí odkaz:
https://doaj.org/article/afbddd025bee472c8522a305ded18559
Autor:
Sara A. Martin, Noelle D. Dwyer, Nadine Michel, Madison R. Hecht, Jessica Neville Little, Katrina C. McNeely, Christopher J. Bott, Kaela S. Lettieri
Publikováno v:
J Neurosci
To build the brain, embryonic neural stem cells (NSCs) tightly regulate their cell divisions, undergoing a polarized form of cytokinesis that is poorly understood. Cytokinetic abscission is mediated by the midbody to sever the daughter cells at the a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fbf1632b24b565ea61293b6503d6b4c3
https://doi.org/10.1523/jneurosci.1955-20.2021
https://doi.org/10.1523/jneurosci.1955-20.2021
Autor:
John H. Moore, Veronica Porterfield, Nathan S. Swami, Armita Salahi, Michael J. McConnell, Nadine Michel, Carlos Honrado
Publikováno v:
ACS sensors. 6(1)
The ability to coax human-induced pluripotent stem cells (hiPSCs) into human neural progenitor cells (hNPCs) can lead to novel drug discovery and transplant therapy platforms for neurological diseases. Since hNPCs can form organoids that mimic brain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49276e89a9e6160de39107387941696c
https://pubmed.ncbi.nlm.nih.gov/33325234
https://pubmed.ncbi.nlm.nih.gov/33325234
Autor:
Katrina C. McNeely, Christopher J. Bott, Kaela S. Lettieri, Nadine Michel, Jessica Neville Little, Noelle D. Dwyer, Madison R. Hecht, Sara A. Martin
To produce a brain of normal size and structure, embryonic neural stem cell (NSCs) must tightly regulate their cell divisions. Cerebral cortex NSCs undergo a polarized form of cytokinesis whose regulation is poorly understood. Cytokinetic abscission
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c330a45b48e06c25fd4ba596e49406e7
https://doi.org/10.1101/2020.06.02.129346
https://doi.org/10.1101/2020.06.02.129346
Publikováno v:
Cytometry A
Somatic mosaicism is a common consequence of normal development. DNA repair is simply not perfect, and each cell's genome incurs continuous DNA damage as a consequence of transcription, replication, and other cell biological stressors. Brain somatic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48b23ef30cd287b5b91567cb08cd118b
https://doi.org/10.1002/cyto.a.23783
https://doi.org/10.1002/cyto.a.23783
Autor:
Nadine Michel, Mark P. Beenhakker, Lise J Harbom, Taylor Rudisill, Michael J. McConnell, Karen A Litwa
Publikováno v:
Cell and tissue research. 375(3)
Induced pluripotent stem cell (iPSC)-derived neurons permit the study of neurogenesis and neurological disease in a human setting. However, the electrophysiological properties of iPSC-derived neurons are consistent with those observed in immature cor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::299225d2b789677bfbc66fb9d4a51284
https://pubmed.ncbi.nlm.nih.gov/30406823
https://pubmed.ncbi.nlm.nih.gov/30406823
Publikováno v:
Molecular and Cellular Neuroscience. 58:53-61
The disruption of neurotransmitter and neurotrophic factor signaling in the central nervous system (CNS) is implicated as the root cause of neuropsychiatric disorders, including schizophrenia, epilepsy, chronic pain, and depression. Therefore, identi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01bdbeee9c68e46585ea59c6e0208663
https://doi.org/10.1016/j.mcn.2013.12.004
https://doi.org/10.1016/j.mcn.2013.12.004
Publikováno v:
IBRO Reports. 6:S89
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::085671b918bb3c455921d196289dff38
https://doi.org/10.1016/j.ibror.2019.07.290
https://doi.org/10.1016/j.ibror.2019.07.290
Autor:
Yves Beauséjour, Nadine Michel
Retrouvez la charmante fratrie de Belle-Rive à la rencontre du célèbre biologiste Shaun Rivière!Le jour de ses onze ans, Victor est d'une humeur massacrante! C'est son premier anniversaire au Manoir de Belle-Rive, sans son père, au milieu d'étr
Autor:
Yves Beauséjour, Nadine Michel
Retrouvez la charmante fratrie de Belle-Rive prête (ou pas) pour affronter la rentrée des classes!C'est un grand jour au Manoir de Belle-Rive : la rentrée scolaire! Les réactions sont mitigées. Angélique refuse de quitter son royaume pour un do