Zobrazeno 1 - 10
of 67
pro vyhledávání: '"Nadine Mestre‐Francés"'
Autor:
Mattia L. DiFrancesco, Manon Marrot, Eleonora Torre, Pietro Mesirca, Romain Davaze, Corinne Lautier, Pascaline Fontes, Joël Cuoq, Anne Fernandez, Ned Lamb, Fabien Pifferi, Nadine Mestre-Francés, Matteo E. Mangoni, Angelo G. Torrente
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-16 (2023)
Abstract Microcebus murinus, or gray mouse lemur (GML), is one of the smallest primates known, with a size in between mice and rats. The small size, genetic proximity to humans and prolonged senescence, make this lemur an emerging model for neurodege
Externí odkaz:
https://doaj.org/article/252330b0209f428c86ff38f1c8a27303
Autor:
Rebecca Grace Fritz, Elke Zimmermann, Martin Meier, Nadine Mestre‐Francés, Ute Radespiel, Daniel Schmidtke
Publikováno v:
Brain and Behavior, Vol 10, Iss 9, Pp n/a-n/a (2020)
Abstract Introduction The gray mouse lemur (Microcebus murinus) is an important nonhuman primate model in biomedical research. Numerous studies investigated mouse lemur behavior and possible factors underlying interindividual variation in both, anima
Externí odkaz:
https://doaj.org/article/8c4a4286923542409cc2594339bf7f74
Autor:
Christelle Lasbleiz, Nadine Mestre-Francés, Gina Devau, Maria-Rosario Luquin, Liliane Tenenbaum, Eric J. Kremer, Jean-Michel Verdier
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 12 (2019)
Parkinson’s disease (PD) is a progressive CNS disorder that is primarily associated with impaired movement. PD develops over decades and is linked to the gradual loss of dopamine delivery to the striatum, via the loss of dopaminergic (DA) neurons i
Externí odkaz:
https://doaj.org/article/690da4a35a0d40b184ac3bc5f5ed66ea
Autor:
Simon Nicot, Anna Bencsik, Eric Morignat, Nadine Mestre-Francés, Armand Perret-Liaudet, Thierry Baron
Publikováno v:
Emerging Infectious Diseases, Vol 18, Iss 12, Pp 2028-2031 (2012)
We compared transmission characteristics for prions from L-type bovine spongiform encephalopathy and MM2-cortical sporadic Creutzfeldt-Jakob disease in the Syrian golden hamster and an ovine prion protein–transgenic mouse line and isolated distinct
Externí odkaz:
https://doaj.org/article/03dcd7b7d2cb49c580e60fc3f4dd4c5e
Autor:
Nadine Mestre-Francés, Simon Nicot, Sylvie Rouland, Anne-Gaëlle Biacabe, Isabelle Quadrio, Armand Perret-Liaudet, Thierry Baron, Jean-Michel Verdier
Publikováno v:
Emerging Infectious Diseases, Vol 18, Iss 1, Pp 142-145 (2012)
We report transmission of atypical L-type bovine spongiform encephalopathy to mouse lemurs after oral or intracerebral inoculation with infected bovine brain tissue. After neurologic symptoms appeared, transmissibility of the disease by both inoculat
Externí odkaz:
https://doaj.org/article/39442fd73fd14292a15a5d8d9924a85a
Autor:
Joan Torrent, Chadi Soukkarieh, Guy Lenaers, Carl Arndt, Valérie Forster, Serge Picaud, Nadine Mestre-Francés, Jean-Michel Verdier
Publikováno v:
Neurobiology of Disease, Vol 39, Iss 2, Pp 211-220 (2010)
No effective treatment currently exists for prion diseases and therefore the development of experimental non-human primate models of prion neurotoxicity, to better understand the underlying mechanism and to test new treatments relevant to humans, rep
Externí odkaz:
https://doaj.org/article/cfd9664987c945889a37527e85ab2906
Autor:
Ronza Abdel Rassoul, Sabine Alves, Véronique Pantesco, John De Vos, Bernard Michel, Martine Perret, Nadine Mestre-Francés, Jean-Michel Verdier, Gina Devau
Publikováno v:
PLoS ONE, Vol 5, Iss 9, Pp 3307-3314 (2010)
Aging is the primary risk factor of neurodegenerative disorders such as Alzheimer's disease (AD). However, the molecular events occurring during brain aging are extremely complex and still largely unknown. For a better understanding of these age-asso
Externí odkaz:
https://doaj.org/article/ae1997bb77b34d3daf3e567238fc81d0
Autor:
Nadine Mestre-Francés, Emeline Keller, Alphonse Calenda, Hélène Barelli, Frédéric Checler, Noëlle Bons
Publikováno v:
Neurobiology of Disease, Vol 7, Iss 1, Pp 1-8 (2000)
Recent reports have shown that amyloid β deposits in the brains of Alzheimer's disease patients consist mainly of two distinct species of amyloid β protein (Aβ) with different C-termini, Aβ1–42 (Aβ42) and Aβ1–40 (Aβ40). The nature of the A
Externí odkaz:
https://doaj.org/article/0219ba4a80274341af5d2923db962951
Autor:
Alphonse Calenda, Nadine Mestre-Francés, Christian Czech, Laurent Pradier, Arlette Petter, Martine Perret, Noëlle Bons, Michel Bellis
Publikováno v:
Neurobiology of Disease, Vol 5, Iss 5, Pp 323-333 (1998)
A 1340-bp cDNA fragment encoding the lemurian presenilin 2 protein (PS2) was isolated from aMicrocebus murinusbrain cDNA library by PCR using oligonucleotide primers based on the nucleotide sequence of the human gene. Analysis of five isolated clones
Externí odkaz:
https://doaj.org/article/7694b2a297c34f68948f543da6971b24
Autor:
Anne Bertrand, Adrien Pasquier, Alexandra Petiet, Christopher Wiggins, Audrey Kraska, Nelly Joseph-Mathurin, Fabienne Aujard, Nadine Mestre-Francés, Marc Dhenain
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e56593 (2013)
Mouse lemurs are non-human primate models of cerebral aging and neurodegeneration. Much smaller than other primates, they recapitulate numerous features of human brain aging, including progressive cerebral atrophy and correlation between regional atr
Externí odkaz:
https://doaj.org/article/1c608f09251f48288e7f34e329581b88