Integrated multi-omics analysis of oligodendroglial tumours identifies three subgroups of 1p/19q co-deleted gliomas

Autor: Aurélie Kamoun, Ahmed Idbaih, Caroline Dehais, Nabila Elarouci, Catherine Carpentier, Eric Letouzé, Carole Colin, Karima Mokhtari, Anne Jouvet, Emmanuelle Uro-Coste, Nadine Martin-Duverneuil, Marc Sanson, Jean-Yves Delattre, Dominique Figarella-Branger, Aurélien de Reyniès, François Ducray, POLA network

Publikováno v: Nature Communications, Vol 7, Iss 1, Pp 1-11 (2016)

Oligodendroglial tumours are characterized into three different molecular subtypes. Here, the authors use genomic data to identify a further three subgroups of 1p/19q co-deleted tumours and demonstrate an association with an aggressive phenotype.

Externí odkaz: https://doaj.org/article/12858698deb1459690d2e7186bf25ef2

Eye movement abnormalities in neurodegenerative langerhans cell histiocytosis

Autor: Lila Autier, Bertrand Gaymard, Eléonore Bayen, Antoine Del Cul, Fleur Cohen-Aubart, Nadine Martin-Duverneuil, Julien Haroche, Karima Mokhtari, Sébastien Héritier, Jean Donadieu, Khê Hoang-Xuan, Ahmed Idbaih

Publikováno v: Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical NeurophysiologyReferences. 43(11)

Langerhans cell histiocytosis (LCH) is a rare inflammatory myeloid neoplasm characterized by proliferation of tumor histiocytes that involves multiple organs including central nervous system. The physiopathologic process underlying degenerative neuro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d3a37ecd708872824471fa3012b6b81
https://pubmed.ncbi.nlm.nih.gov/35760933

Molecular Profiling Reclassifies Adult Astroblastoma into Known and Clinically Distinct Tumor Entities with Frequent Mitogen-Activated Protein Kinase Pathway Alterations

Autor: Franck Bielle, Mehdi Touat, Karima Mokhtari, Aurélien Nouet, Yannick Marie, Philipp Euskirchen, Audrey Rousseau, Luc Taillandier, William Boisseau, Justine Guegan, Marc Sanson, Caroline Dehais, Carine Karachi, Ahmed Idbaih, Nadine Martin-Duverneuil, Laurent Capelle, Khê Hoang-Xuan, Jean-Yves Delattre

Publikováno v: Oncologist
Oncologist, AlphaMed Press, In press, ⟨10.1634/theoncologist.2019-0223⟩

BackgroundAstroblastoma (ABM) is a rare glial brain tumor. Recurrent meningioma 1 (MN1) alterations have been recently identified in most pediatric cases. Adolescent and adult cases, however, remain molecularly poorly defined.Materials and MethodsWe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc6f642acca95087cc63d27b1ae453aa
https://doi.org/10.1634/theoncologist.2019-0223

MRI features of intra-axial histiocytic brain mass lesions

Autor: Jean Donadieu, Khê Hoang-Xuan, Damien Galanaud, Didier Dormont, Nafi Aygun, Aurélie Drier, Karima Mokhtari, Julien Haroche, Licia P. Luna, Nadine Martin-Duverneuil

Publikováno v: Clinical Radiology
Clinical Radiology, WB Saunders, 2021, 76 (2), pp.159.e19-159.e28. ⟨10.1016/j.crad.2020.09.015⟩
Clinical Radiology, 2021, 76 (2), pp.159.e19-159.e28. ⟨10.1016/j.crad.2020.09.015⟩

AIM To describe MRI features, including diffusion-weighted imaging (DWI), magnetic resonance spectroscopy (MRS), and perfusion-weighted imaging (PWI), of intra-axial tumour-like presentations of four different subtypes of histiocytosis. MATERIAL AND

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::feb42ea80a07b2dc9d21937fb68d920f
https://hal.archives-ouvertes.fr/hal-03139272

Neurological diseases of unknown etiology: Brain-biopsy diagnostic yields and safety

Autor: Bertrand Mathon, Alexandre Le Joncour, Franck Bielle, Karima Mokhtari, Anne-Laure Boch, Matthieu Peyre, Zahir Amoura, Patrice Cacoub, Nadia Younan, Sophie Demeret, Eimad Shotar, Sonia Burrel, Arnaud Fekkar, Jérôme Robert, Aymeric Amelot, Marc Pineton de Chambrun, Alexandre Carpentier, Laurent Capelle, Soledad Navarro, Olivier Benveniste, Dimitri Psimaras, Khê Hoang-Xuan, Jean-Yves Delattre, Nicolas Weiss, Clémence Marois, Sarah Benghanem, Nadine Martin-Duverneuil, Véronique Leblond, Sylvain Choquet, Charles-Edouard Luyt, Alain Combes, Eric Caumes, Vincent Calvez, Aude Jary, Renaud Piarroux, Alexandra Aubry, Vincent Degos, Alice Jacquens, Caroline Papeix, Vincent Navarro

Publikováno v: European Journal of Internal Medicine
European Journal of Internal Medicine, Elsevier, 2020, 80, pp.78-85. ⟨10.1016/j.ejim.2020.05.029⟩

International audience; Background: For nonneoplastic neurological diseases, no recommendation exists regarding the place or appropriate timing of brain biopsy. The aim of this study was to evaluate the diagnostic yield and safety of brain biopsies f

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e30e97902fe3001234b2ef6d346e266
https://hal.sorbonne-universite.fr/hal-02946474/document