Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Nadine Kliese"'
Autor:
Christian Mawrin, Elmar Kirches, Annette Wilisch-Neumann, Oliver Stork, Frank Angenstein, Nadine Kliese, Nadine Andrae, Doreen Pachow
PDF file - 65K, Effect of temsirolimus in a subcutaneous xenograft mouse model
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4955f734c1f5b59bfdba3f0ceb043277
https://doi.org/10.1158/1078-0432.22448777.v1
https://doi.org/10.1158/1078-0432.22448777.v1
Autor:
Christian Mawrin, Elmar Kirches, Cornelia Helbing, Diana Pasemann, Peter Hass, Frank-Dietmar Böhmer, Werner EK Braunsdorf, Jan-Peter Warnke, Thomas Schneider, Doreen Pachow, Nadine Kliese, Annette Wilisch-Neumann
Purpose: Meningiomas are frequent intracranial or spinal neoplasms, which recur frequently and can show aggressive clinical behaviour. We elucidated the impact of the integrin inhibitor cilengitide on migration, proliferation, and radiosensitization
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dadb72e040d297f2e93460fea31975ba
https://doi.org/10.1158/1078-0432.c.6521400
https://doi.org/10.1158/1078-0432.c.6521400
Autor:
Christian Mawrin, Elmar Kirches, Cornelia Helbing, Diana Pasemann, Peter Hass, Frank-Dietmar Böhmer, Werner EK Braunsdorf, Jan-Peter Warnke, Thomas Schneider, Doreen Pachow, Nadine Kliese, Annette Wilisch-Neumann
Supplementary Figure 1 - PDF file 57K, integrin mRNA expression in meningiomas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a0283af208c75bdcad1dae5b16f37d3
https://doi.org/10.1158/1078-0432.22448442.v1
https://doi.org/10.1158/1078-0432.22448442.v1
Autor:
Christian Mawrin, Elmar Kirches, Annette Wilisch-Neumann, Oliver Stork, Frank Angenstein, Nadine Kliese, Nadine Andrae, Doreen Pachow
PDF file - 69K, Real time-PCR primer sequences
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0640ccf264982b7473425f8b4a26c18b
https://doi.org/10.1158/1078-0432.22448780.v1
https://doi.org/10.1158/1078-0432.22448780.v1
Autor:
Christian Mawrin, Elmar Kirches, Cornelia Helbing, Diana Pasemann, Peter Hass, Frank-Dietmar Böhmer, Werner EK Braunsdorf, Jan-Peter Warnke, Thomas Schneider, Doreen Pachow, Nadine Kliese, Annette Wilisch-Neumann
Supplementary Figure 3 - PDF file 43K, Overall survival of mice treated with cilengitide and control animals
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d62ffa2bf41711aa8e79ae449192319
https://doi.org/10.1158/1078-0432.22448436
https://doi.org/10.1158/1078-0432.22448436
Autor:
Christian Mawrin, Elmar Kirches, Cornelia Helbing, Diana Pasemann, Peter Hass, Frank-Dietmar Böhmer, Werner EK Braunsdorf, Jan-Peter Warnke, Thomas Schneider, Doreen Pachow, Nadine Kliese, Annette Wilisch-Neumann
Supplementary Figure 2 - PDF file 128K, Cell cycle analyses under cilengitide treatment. Meningioma cell lines treated with cilengitide and analysed for cell cycle changes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::734c2b2fd4fc77316694dc2c55f71768
https://doi.org/10.1158/1078-0432.22448439.v1
https://doi.org/10.1158/1078-0432.22448439.v1
Autor:
Christian Mawrin, Elmar Kirches, Annette Wilisch-Neumann, Oliver Stork, Frank Angenstein, Nadine Kliese, Nadine Andrae, Doreen Pachow
Purpose: To evaluate the mTORC1 (mammalian target of rapamycin complex 1) pathway in meningiomas and to explore mTORC1 as a therapeutic target in meningioma cell lines and mouse models.Experimental Design: Tissue microarrays (53 meningiomas of all WH
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::737c54afacb6895f24e318fe97f850ed
https://doi.org/10.1158/1078-0432.c.6521483.v1
https://doi.org/10.1158/1078-0432.c.6521483.v1
Autor:
Christian Mawrin, Annette Wilisch-Neumann, Oliver Stork, Nadine Kliese, Frank Angenstein, Nadine Andrae, Elmar Kirches, Doreen Pachow
Publikováno v:
Clinical Cancer Research. 19:1180-1189
Purpose: To evaluate the mTORC1 (mammalian target of rapamycin complex 1) pathway in meningiomas and to explore mTORC1 as a therapeutic target in meningioma cell lines and mouse models. Experimental Design: Tissue microarrays (53 meningiomas of all W
Autor:
Doreen Pachow, Eckart Meese, D. Panayotova-Dimitrova, Frank Angenstein, Nadine Kliese, Markus J. Riemenschneider, P. Gobrecht, Elmar Kirches, Nadine Andrae, Christian Mawrin, David H. Gutmann, M. Riek-Burchardt, Annette Wilisch-Neumann, Guido Reifenberger
Publikováno v:
Oncogene. 32:4712-4720
Meningiomas are frequent, mostly benign intracranial or spinal tumors. A small subset of meningiomas is characterized by histological features of atypia or anaplasia that are associated with more aggressive biological behavior resulting in increased
Autor:
Nadine Kliese, Yvonn Stampnik, Yan Cui, Astrid Petermann, Frank-D. Böhmer, Doreen Pachow, Christian Mawrin, Helen Morrison
Publikováno v:
Journal of neuro-oncology. 122(3)
Brain-invasive growth of a subset of meningiomas is associated with less favorable prognosis. The molecular mechanisms causing invasiveness are only partially understood, however, the expression of matrix metalloproteinases (MMPs) has been identified