Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Nadine Horstick-Muche"'
Autor:
Andrea Schöler, Thomas Kurz, Sanil Bhatia, Jing Yang, Nadine Horstick-Muche, Finn K. Hansen, Alexandra Hamacher, Melf Sönnichsen, Arndt Borkhardt, Marc Pflieger, Matthias U. Kassack, Julian Schliehe-Diecks
Publikováno v:
Chemmedchem
The acetylome is important for maintaining the homeostasis of cells. Abnormal changes can result in the pathogenesis of immunological or neurological diseases, and degeneration can promote the manifestation of cancer. In particular, pharmacological i
Autor:
Matthias U. Kassack, Leandro A. Alves-Avelar, Thomas Kurz, Stefan Klinken, Beate Lungerich, Nadine Horstick-Muche, Yodita Asfaha, Alexander Jan Skerhut
Publikováno v:
Arkivoc. 2020:228-241
Autor:
Benedikt Boesen, Alexandra Hamacher, Thomas Kurz, Nadine Horstick-Muche, Matthias U. Kassack, Taner Öz, Marc Pflieger, Christian Schrenk
Publikováno v:
Bioorganic & Medicinal Chemistry. 27:115036
A series of α,β-unsaturated hydroxamic acid derivatives as novel HDAC inhibitors (HDACi) with structural modifications of the connecting unit and the CAP group was synthesized. The in vitro evaluation against the human cancer cell lines A2780 and C