Cold-stimulated brown adipose tissue activation is related to changes in serum metabolites relevant to NAD+ metabolism in humans

Autor: Mueez U-Din, Vanessa D. de Mello, Marjo Tuomainen, Juho Raiko, Tarja Niemi, Tobias Fromme, Anton Klåvus, Nadine Gautier, Kimmo Haimilahti, Marko Lehtonen, Karsten Kristiansen, John W. Newman, Kirsi H. Pietiläinen, Jussi Pihlajamäki, Ez-Zoubir Amri, Martin Klingenspor, Pirjo Nuutila, Eija Pirinen, Kati Hanhineva, Kirsi A. Virtanen

Publikováno v: Cell Reports, Vol 42, Iss 9, Pp 113131- (2023)

Summary: Cold-induced brown adipose tissue (BAT) activation is considered to improve metabolic health. In murine BAT, cold increases the fundamental molecule for mitochondrial function, nicotinamide adenine dinucleotide (NAD+), but limited knowledge

Externí odkaz: https://doaj.org/article/1c0fa9c527de49b8bd7b766598b67913

Long-Term Fate and Efficacy of a Biomimetic (Sr)-Apatite-Coated Carbon Patch Used for Bone Reconstruction

Autor: Florian Olivier, Christophe Drouet, Olivier Marsan, Vincent Sarou-Kanian, Samah Rekima, Nadine Gautier, Franck Fayon, Sylvie Bonnamy, Nathalie Rochet

Publikováno v: Journal of Functional Biomaterials, Vol 14, Iss 5, p 246 (2023)

Critical bone defect repair remains a major medical challenge. Developing biocompatible materials with bone-healing ability is a key field of research, and calcium-deficient apatites (CDA) are appealing bioactive candidates. We previously described a

Externí odkaz: https://doaj.org/article/2a98ed7ac2f146c390c24e123c86d988

The Rosmarinus Bioactive Compound Carnosic Acid Is a Novel PPAR Antagonist That Inhibits the Browning of White Adipocytes

Autor: Cécilia Colson, Pierre-Louis Batrow, Nadine Gautier, Nathalie Rochet, Gérard Ailhaud, Franck Peiretti, Ez-Zoubir Amri

Publikováno v: Cells, Vol 9, Iss 11, p 2433 (2020)

Thermogenic brown and brite adipocytes convert chemical energy from nutrients into heat. Therapeutics that regulate brown adipocyte recruitment and activity represent interesting strategies to control fat mass such as in obesity or cachexia. The pero

Externí odkaz: https://doaj.org/article/f2956457bbd34751a84fa6d39dd9bba9

Long Read Sequencing Technology to Solve Complex Genomic Regions Assembly in Plants

Autor: Nadege Arnal, Genseric Beydon, Elisa Prat, Nathalie Rodde, Yves Barrière, Nadine Gautier, Arnaud Bellec, Joëlle Fourment, Audrey Courtial, William Mar, Sonia Vautrin, Stéphane Cauet, Hélène Bergès

Publikováno v: Journal of Next Generation Sequencing and Applications
Journal of Next Generation Sequencing and Applications, 2016, 3 (2), pp.1-13. ⟨10.4172/2469-9853.1000128⟩
Journal of Next Generation Sequencing and Applications 2 (3), 1-13. (2016)

Background: Numerous completed or on-going whole genome sequencing projects have highlighted the fact that obtaining a high quality genome sequence is necessary to address comparative genomics questions such as structural variations among genotypes a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93bccb88c0d29849e1c13adb3ffb0847
https://doi.org/10.4172/2469-9853.1000128

Expression of a prenylation-deficient Rab4 inhibits the GLUT4 translocation induced by active phosphatidylinositol 3-kinase and protein kinase B

Autor: Mireille CORMONT, Nadine GAUTIER, Karine ILC, Yannick Le MARCHAND-BRUSTEL

Publikováno v: Biochemical Journal. 356:143-149

The small GTPase Rab4 has been shown to participate in the subcellular distribution of GLUT4 under both basal and insulin-stimulated conditions in adipocytes. In the present work, we have characterized the effect of Rab4 ΔCT, a prenylation-deficient

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::abf0da734f02ea7f9ba024ebb485eb04
https://doi.org/10.1042/bj3560143