Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Nadine Fournier"'
Autor:
Anissa Fries, Fanny Saidoune, François Kuonen, Isabelle Dupanloup, Nadine Fournier, Ana Cristina Guerra de Souza, Muzlifah Haniffa, Feiyang Ma, Johann E. Gudjonsson, Lennart Roesner, Yang Li, Thomas Werfel, Curdin Conrad, Raphael Gottardo, Robert L. Modlin, Jeremy Di Domizio, Michel Gilliet
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
Abstract Interleukin (IL)-26 is a TH17 cytokine with known antimicrobial and pro-inflammatory functions. However, the precise role of IL-26 in the context of pathogenic TH17 responses is unknown. Here we identify a population of blood TH17 intermedia
Externí odkaz:
https://doaj.org/article/9a6badc4e12148d591a4960524014626
Autor:
Katarina Pinjusic, Giovanna Ambrosini, Joao Lourenco, Nadine Fournier, Christian Iseli, Nicolas Guex, Olga Egorova, Sina Nassiri, Daniel B. Constam
Publikováno v:
Frontiers in Immunology, Vol 14 (2024)
The transforming growth factor-β (TGF-β) family member activin A (hereafter Activin-A) is overexpressed in many cancer types, often correlating with cancer-associated cachexia and poor prognosis. Activin-A secretion by melanoma cells indirectly imp
Externí odkaz:
https://doaj.org/article/a5db1bfb7f9b490ca34d6dec0642efd3
Autor:
Dominik Guggisberg, Kathryn J. Burton-Pimentel, Barbara Walther, René Badertscher, Carola Blaser, Reto Portmann, Alexandra Schmid, Thomas Radtke, Hugo Saner, Nadine Fournier, Ueli Bütikofer, Guy Vergères
Publikováno v:
Lipids in Health and Disease, Vol 21, Iss 1, Pp 1-19 (2022)
Abstract Background Whereas the dietary intake of industrial trans fatty acids (iTFA) has been specifically associated with inflammation, cardiovascular disease, and type 2 diabetes, understanding the impact of dietary fats on human health remains ch
Externí odkaz:
https://doaj.org/article/567d694940ee4ace8beefe68c72fb7a0
Autor:
Janine Wörthmüller, Simona Disler, Sylvain Pradervand, François Richard, Lisa Haerri, Gustavo A. Ruiz Buendía, Nadine Fournier, Christine Desmedt, Curzio Rüegg
Publikováno v:
Cells, Vol 12, Iss 15, p 1929 (2023)
MAGI1 acts as a tumor suppressor in estrogen receptor-positive (ER+) breast cancer (BC), and its loss correlates with a more aggressive phenotype. To identify the pathways and events affected by MAGI1 loss, we deleted the MAGI1 gene in the ER+ MCF7 B
Externí odkaz:
https://doaj.org/article/c0dd5c8d85c24b8aa4619c329b4d0ec7
Autor:
Vladimir Wischnewski, Roeltje R. Maas, Paola Guerrero Aruffo, Klara Soukup, Giovanni Galletti, Mara Kornete, Sabine Galland, Nadine Fournier, Johanna Lilja, Pratyaksha Wirapati, Joao Lourenco, Alice Scarpa, Roy T. Daniel, Andreas F. Hottinger, Jean-Philippe Brouland, Agnese Losurdo, Emanuele Voulaz, Marco Alloisio, Monika E. Hegi, Enrico Lugli, Johanna A. Joyce
Publikováno v:
Nature Cancer.
The immune-specialized environment of the healthy brain is tightly regulated to prevent excessive neuroinflammation. However, after cancer development, a tissue-specific conflict between brain-preserving immune suppression and tumor-directed immune a
Autor:
Jeremiah Bernier-Latmani, Christophe Cisarovsky, Samantha Mahfoud, Simone Ragusa, Isabelle Dupanloup, David Barras, François Renevey, Sina Nassiri, Pascale Anderle, Mario Leonardo Squadrito, Stefanie Siegert, Suzel Davanture, Alejandra González-Loyola, Nadine Fournier, Sanjiv A. Luther, Rui Benedito, Philippe Valet, Bin Zhou, Michele De Palma, Mauro Delorenzi, Christine Sempoux, Tatiana V. Petrova
Publikováno v:
Nature Cardiovascular Research
Stem and progenitor cells residing in the intestinal crypts drive the majority of colorectal cancers (CRCs), yet vascular contribution to this niche remains largely unexplored. VEGFA is a key driver of physiological and tumor angiogenesis. Accordingl
Autor:
Chen Wang, Coline Barnoud, Mara Cenerenti, Mengzhu Sun, Irene Caffa, Burak Kizil, Ruben Bill, Yuanlong Liu, Robert Pick, Laure Garnier, Olga A. Gkountidi, Louise M. Ince, Stephan Holtkamp, Nadine Fournier, Olivier Michielin, Daniel E. Speiser, Stéphanie Hugues, Alessio Nencioni, Mikaël J. Pittet, Camilla Jandus, Christoph Scheiermann
Publikováno v:
Wang, Chen; Barnoud, Coline; Cenerenti, Mara; Sun, Mengzhu; Caffa, Irene; Kizil, Burak; Bill, Ruben; Liu, Yuanlong; Pick, Robert; Garnier, Laure; Gkountidi, Olga A; Ince, Louise M; Holtkamp, Stephan; Fournier, Nadine; Michielin, Olivier; Speiser, Daniel E; Hugues, Stéphanie; Nencioni, Alessio; Pittet, Mikaël J; Jandus, Camilla; ... (2023). Dendritic cells direct circadian anti-tumor immune responses. Nature, 614(7946), pp. 136-143. Springer Nature 10.1038/s41586-022-05605-0
The process of cancer immunosurveillance is a mechanism of tumour suppression that can protect the host from cancer development throughout its lifetime1,2. However, it is unknown whether the effectiveness of cancer immunosurveillance fluctuates over
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::153c5412fe0197711ec212feccd733e4
https://boris.unibe.ch/176997/1/s41586-022-05605-0_reference.pdf
https://boris.unibe.ch/176997/1/s41586-022-05605-0_reference.pdf
Autor:
Linlin Cao, Gustavo A. Ruiz Buendía, Nadine Fournier, Yuanlong Liu, Florence Armand, Romain Hamelin, Maria Pavlou, Freddy Radtke
Gain-of-function mutations inNOTCH1are among the most frequent genetic alterations in T cell acute lymphoblastic leukemia (T-ALL), making the Notch signaling pathway a promising therapeutic target for personalized medicine. Yet, a major limitation fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1321221ccf5b9a1bde28367280e053c
https://doi.org/10.21203/rs.3.rs-2463403/v1
https://doi.org/10.21203/rs.3.rs-2463403/v1
Autor:
Qiqun Zeng, Sadegh Saghafinia, Agnieszka Chryplewicz, Nadine Fournier, Lucine Christe, Yu-Qing Xie, Jeremy Guillot, Simge Yucel, Pumin Li, José A. Galván, Eva Karamitopoulou, Inti Zlobec, Dalya Ataca, Fleuriane Gallean, Peng Zhang, José Antonio Rodriguez-Calero, Mark Rubin, Mélanie Tichet, Krisztian Homicsko, Douglas Hanahan
Publikováno v:
Science (New York, N.Y.). 378(6621)
Many human cancers manifest the capability to circumvent attack by the adaptive immune system. In this work, we identified a component of immune evasion that involves frequent up-regulation of fragile X mental retardation protein (FMRP) in solid tumo
Autor:
Sanam Peyvandi, Manon Bulliard, Annamaria Kauzlaric, Oriana Coquoz, Yu-Ting Huang, Nathalie Duffey, Laetitia Gafner, Girieca Lorusso, Nadine Fournier, Qiang Lan, Curzio Rüegg
Cancer cell plasticity contributes to tumor therapy resistance and metastasis formation, which represent the main causes of cancer-related death for most cancers, including breast cancer. The tumor microenvironment drives cancer cell plasticity and m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ecedfb760af56985f3dfcaf3f9a9601c
https://doi.org/10.1101/2022.10.26.513889
https://doi.org/10.1101/2022.10.26.513889