Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Nadine Dreser"'
Autor:
Florian Seidel, Anna Cherianidou, Franziska Kappenberg, Miriam Marta, Nadine Dreser, Jonathan Blum, Tanja Waldmann, Nils Blüthgen, Johannes Meisig, Katrin Madjar, Margit Henry, Tamara Rotshteyn, Andreas Scholtz-Illigens, Rosemarie Marchan, Karolina Edlund, Marcel Leist, Jörg Rahnenführer, Agapios Sachinidis, Jan Georg Hengstler
Publikováno v:
Cells, Vol 11, Iss 21, p 3404 (2022)
Human-relevant tests to predict developmental toxicity are urgently needed. A currently intensively studied approach makes use of differentiating human stem cells to measure chemically-induced deviations of the normal developmental program, as in a r
Externí odkaz:
https://doaj.org/article/1c72b068b68a48ac9b8dc05a0289a26b
Autor:
Petra Kranaster, Nadine Dreser, Christian Dietz, David Kolb, Johannes Meisig, Margit Henry, Marcel Leist, Simon Gutbier, Christoph van Thriel, Jörg Rahnenführer, Christopher Scholz, Michael R. Berthold, Marion Kapitza, Katrin Madjar, Agapios Sachinidis, Jan G. Hengstler, Timo Trefzer, Nils Blüthgen, Anna-Katharina Holzer, Tanja Waldmann, Stefanie Klima
Publikováno v:
Archives of Toxicology
The first in vitro tests for developmental toxicity made use of rodent cells. Newer teratology tests, e.g. developed during the ESNATS project, use human cells and measure mechanistic endpoints (such as transcriptome changes). However, the toxicologi
Autor:
André König, Agapios Sachinidis, Jörg Rahnenführer, Marcel Leist, Stefan Schildknecht, Jan G. Hengstler, Margit Henry, Marianna Grinberg, Tanja Waldmann, Vaibhav Shinde, Eugen Rempel, Nadine Dreser, Anna-Katharina Holzer
Publikováno v:
Chemical Research in Toxicology
Analysis of transcriptome changes has become an established method to characterize the reaction of cells to toxicants. Such experiments are mostly performed at compound concentrations close to the cytotoxicity threshold. At present, little informatio
Autor:
Johannes Meisig, Tanja Waldmann, Christian Dietz, Nadine Dreser, Bastian Zimmer, Giorgia Pallocca, Johanna Nyffeler, Elena Sügis, Nils Blüthgen, Marcel Leist, Michael R. Berthold
Publikováno v:
Neurotoxicology. 50
Functional assays, such as the “migration inhibition of neural crest cells” (MINC) developmental toxicity test, can identify toxicants without requiring knowledge on their mode of action (MoA). Here, we were interested, whether (i) inhibition of
Autor:
Tanja Waldmann, Agapios Sachinidis, C. van Thriel, Marcel Leist, Jan G. Hengstler, Nadine Dreser, Sunniva Foerster, Karl-Heinz Krause, Joost Westerhout, Giorgia Pallocca, Stéphanie Julien, Sieto Bosgra, Bastian Zimmer
Publikováno v:
Archives of Toxicology, Vol. 88, No 5 (2014) pp. 1109-1126
Archives of Toxicology, 5, 88, 1109-1126
Archives of Toxicology
Archives of Toxicology, 5, 88, 1109-1126
Archives of Toxicology
Developmental toxicity in vitro assays have hitherto been established as stand-alone systems, based on a limited number of toxicants. Within the embryonic stem cell-based novel alternative tests project, we developed a test battery framework that all