Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Nadine Dietrich"'
Autor:
Ying Chen, Andrea Schlotterer, Jihong Lin, Nadine Dietrich, Thomas Fleming, Stefanie Lanzinger, Reinhard W. Holl, Hans-Peter Hammes
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract This study aimed to characterize the role of female sex in the pathogenesis of diabetic retinopathy. In the retinae of female Ins2Akita-diabetic mice (F-IA), ovariectomized female Ins2Akita-diabetic mice (F-IA/OVX), male Ins2Akita-diabetic m
Externí odkaz:
https://doaj.org/article/1fcfdcfe20df49a6a7fb046a3c33ff84
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Background: Zebrafish (Danio rerio) have been established in recent years as a model organism to study Diabetic Retinopathy (DR). Loss of endothelial cells and pericytes is an early hallmark sign of developing DR in the mammalian retina. However, mor
Externí odkaz:
https://doaj.org/article/87c20a644e4b4b2da99c83d28f8e16d8
Autor:
Robin Sachdeva, Andrea Schlotterer, Dagmar Schumacher, Christin Matka, Ilka Mathar, Nadine Dietrich, Rebekka Medert, Ulrich Kriebs, Jihong Lin, Peter Nawroth, Lutz Birnbaumer, Thomas Fleming, Hans-Peter Hammes, Marc Freichel
Publikováno v:
Molecular Metabolism, Vol 9, Iss , Pp 156-167 (2018)
Objective: Diabetic retinopathy (DR) is induced by an accumulation of reactive metabolites such as ROS, RNS, and RCS species, which were reported to modulate the activity of cation channels of the TRPC family. In this study, we use Trpc1/4/5/6−/−
Externí odkaz:
https://doaj.org/article/6e5ee3b073824294af4b0ed7ec6a90ef
Autor:
Nadine Dietrich, Matthias Kolibabka, Stephanie Busch, Petra Bugert, Ulrike Kaiser, Jihong Lin, Thomas Fleming, Michael Morcos, Thomas Klein, Andrea Schlotterer, Hans-Peter Hammes
Publikováno v:
PLoS ONE, Vol 11, Iss 12, p e0167853 (2016)
Dipeptidyl peptidase 4 (DPP4) inhibitors improve glycemic control in type 2 diabetes, however, their influence on the retinal neurovascular unit remains unclear.Vasculo- and neuroprotective effects were assessed in experimental diabetic retinopathy a
Externí odkaz:
https://doaj.org/article/0b6cee6f287743b58ed603000740febd
Autor:
Nadine Dietrich
Publikováno v:
English Language and Linguistics. :1-7
Autor:
Liying, An, Julia, Michaeli, Prama, Pallavi, Annette, Breedijk, Xin, Xu, Nadine, Dietrich, Martin, Sigl, Michael, Keese, Katja, Nitschke, Jonas, Jarczyk, Philipp, Nuhn, Bernhard K, Krämer, Benito A, Yard, Jan, Leipe
Publikováno v:
Journal of Leukocyte Biology. 112:437-447
In atherosclerotic lesions, macrophages are exposed to CSFs and various microenvironmental cues, which ultimately drive their polarization state. We studied the expression of different CSFs in artery specimen and cultured vascular cells and assessed
Publikováno v:
Hand in Hand zum Ziel – einfach.besser.messbar www.diabeteskongress.de.
Autor:
Nadine Dietrich, Tobias Huth, Patrick Krauss, Dominik Oliver, Tobias Moser, Michael G. Leitner, Holger Schulze, Marlen Dierich, Stephanie Hartmann, Achim Schilling, Konstantin Tziridis, Michael J.F. Blumer, Franziska Brede, Christian Alzheimer, Sandra Karch, Sabine Hessler, Anneliese Schrott-Fischer, Carmen Birchmeier, Lejo Johnson Chacko, Philip Moeser
Publikováno v:
J Neurosci
Cleavage of amyloid precursor protein (APP) by β-secretase BACE1 initiates the production and accumulation of neurotoxic amyloid-β peptides, which is widely considered an essential pathogenic mechanism in Alzheimer's disease (AD). Here, we report t
Publikováno v:
European Journal of Developmental Psychology. 3:222-237
In two experiments, 2- to 4-year-old children's understanding of knowing and guessing was studied in a non-verbal task, requiring the choice of a helper in a hide-and-seek task. Results indicate marked developmental progress in the age range between
Autor:
Nadine, Dietrich, Hans-Peter, Hammes
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 933
Retinal digestion is a commonly used method for studying experimental diabetic retinopathy in animal models. The method allows to assess qualitatively and quantitatively the morphology of the retinal vasculature, including characteristics of endothel