Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Nadine Derrien"'
Autor:
Wietfeld Bernhard, Florian Kleinbeck, Jingjing Wu, Liqun Zhao, Francesco Venturoni, Weichun Liu, Xiangguang Tian, Gai Yu, Paolo Filipponi, Thomas Ruch, Nikola Kovacic, Bertrand Guelat, Philippe Piechon, Guanghua Jia, Xi Luo, Junjie Sun, Feng Gao, Xin Gu, Jianghua Zhang, Hai Dong, Thierry Schlama, Nadine Derrien, Thomas Allmendinger, Xiaoquan Lu, Bo Yu, Hongwei Yang, Huijuan Gu, Xuesong Zhang, Huaimin Wang, Yunzhong Li, Pascale Hoehn, Like Chen, Yingtao Tian, Su Xu, Luca Hermann, Berthold Schenkel, Shengqing Ye, Yan Wang, Xingxian Gu, Xufan Wang, Meng Chang, Min Zhongcheng, Jibin Zhao
Publikováno v:
The Journal of organic chemistry. 85(11)
LCZ696 is a novel treatment for patients suffering from heart failure that combines the two active pharmaceutical ingredients sacubitril and valsartan in a single chemical compound. While valsartan is an established drug substance, a new manufacturin
Autor:
David A. Chaplin, Nadine Derrien, Raymond McCague, Michael C. Lloyd, Stephen Taylor, Mark E. B. Smith
Publikováno v:
Tetrahedron Letters. 42:1347-1350
The use of both N-tert-butoxycarbonylamino- and hydroxyl-directed hydrogenation methodology to yield essentially single diastereomers of 3-(tert-butoxycarbonylamino)-4-hydroxycyclopentanecarboxylic acid methyl esters and 3-(tert-butoxycarbonylamino)c
Autor:
Mark J. Burk, Stanley M. Roberts, Nadine Derrien, Cyril B. Dousson, Ulrich Berens, Manuela Ohff
Publikováno v:
Tetrahedron: Asymmetry. 10:3341-3352
The bicyclic alcohol (−)- 4 was prepared from (−)-bicyclo[3.2.0]hept-2-en-6-one (−)- 1 in 50% yield. The diol (−)- 4 was coupled to selected chlorophosphines 6 – 12 to produce a series of bisphosphinites 13 – 19 in 89–95% yield. From th
Publikováno v:
Journal of Organometallic Chemistry. 551:151-157
The catalytic activation of pro-2-ynylic ethers HCCCR 2 OMe towards carboxylic acids is controlled to regioselectively afford the functional enol esters R 1 CO 2 C(CH 2 )CR 2 OMe or R 1 CO 2 CHCHCR 2 OMe corresponding to the addition of the
Autor:
Nadine Derrien, Vincent Ferrand, Carsten Bolm, Céline Gambs, Georg Süss-Fink, Helen Stoeckli-Evans
Publikováno v:
Journal of Organometallic Chemistry. 549:275-282
The reaction of the electron-deficient cluster ( μ 2 -H)Ru 3 (CO) 9 [ μ 3 -NS(O)MePh] ( 1 ) with para -nitrotolane gives, with coupling of two alkyne units and elimination of the para -nitrophenyl fragment, the trinuclear complexes Ru 3 (CO) 9 [ μ
Autor:
Nadine Derrien, Richard C. Lloyd, Raymond McCague, Mark E. B. Smith, Michael C. Lloyd, Guy Casy, Stephen Taylor, David A. Chaplin
Publikováno v:
Tetrahedron: Asymmetry. 12:703-705
A route to all eight stereoisomers of 3-( tert -butoxycarbonylamino)-4-hydroxycyclopentanecarboxylic acid methyl ester is presented; these products should prove to be valuable scaffolds in pharmaceutical discovery.
Autor:
Stanley M. Roberts, Ulrich Berens, Manuela Ohff, Cyril B. Dousson, Mark J. Burk, Nadine Derrien
Publikováno v:
ChemInform. 31
The bicyclic alcohol (−)- 4 was prepared from (−)-bicyclo[3.2.0]hept-2-en-6-one (−)- 1 in 50% yield. The diol (−)- 4 was coupled to selected chlorophosphines 6 – 12 to produce a series of bisphosphinites 13 – 19 in 89–95% yield. From th
Publikováno v:
ChemInform. 31
Optically active dendritic amino alcohols catalyse the enantioselective borane reduction of ketones with good yields and high enantiomeric excesses.
Publikováno v:
Chemical Communications. :2087-2088
Optically active dendritic amino alcohols catalyse the enantioselective borane reduction of ketones with good yields and high enantiomeric excesses.