Zobrazeno 1 - 8 of 8 pro vyhledávání: '"Nadine D, van Kleef"'
1
Akademický článek
Gene network-based and ensemble modeling-based selection of tumor-associated antigens with a predicted low risk of tissue damage for targeted immunotherapy
Autor: Carola Berking, Gerold Schuler, Olaf Wolkenhauer, Annelies W Turksma, Heiko Bruns, Julio Vera, Martin Eberhardt, Manuel Wiesinger, Beatrice Schuler-Thurner, Cindy Flamann, Markus Vincent Heppt, Shailendra Gupta, Christopher Lischer, Johannes Berges, Esther Güse, Anja Wessely, Adrian Weich, Jimmy Retzlaff, Jan Dörrie, Niels Schaft, Johannes März, Harald Knorr, Krishna Pal Singh, Elias Andreas Thomas Koch, Nadine D van Kleef, Julian J Freen-van Heeren, Bettina Hohberger
Publikováno v: Journal for ImmunoTherapy of Cancer, Vol 12, Iss 5 (2024)
Background Tumor-associated antigens and their derived peptides constitute an opportunity to design off-the-shelf mainline or adjuvant anti-cancer immunotherapies for a broad array of patients. A performant and rational antigen selection pipeline wou
Externí odkaz: https://doaj.org/article/f5b73ac9110f43bf9d82c89934e31442
Zobrazit plný text záznamu
2
Akademický článek
S100A8/A9 Is a Marker for the Release of Neutrophil Extracellular Traps and Induces Neutrophil Activation
Autor: Evelien G. G. Sprenkeler, Judith Zandstra, Nadine D. van Kleef, Ines Goetschalckx, Bibian Verstegen, Cathelijn E. M. Aarts, Hans Janssen, Anton T. J. Tool, Gerard van Mierlo, Robin van Bruggen, Ilse Jongerius, Taco W. Kuijpers
Publikováno v: Cells, Vol 11, Iss 2, p 236 (2022)
Neutrophils are the most abundant innate immune cells in the circulation and they are the first cells recruited to sites of infection or inflammation. Almost half of the intracellular protein content in neutrophils consists of S100A8 and S100A9, thou
Externí odkaz: https://doaj.org/article/234f49adf7704329aa6b927e21835fc8
Zobrazit plný text záznamu
4
Targeted SERPIN (TaSER): A dual‐action antithrombotic agent that targets platelets for SERPIN delivery
Autor: Minka Zivkovic, Mark Roest, Thomas Renné, Chantal C. Clark, Arjan D. Barendrecht, Coen Maas, Hinde El Otmani, Simone M. Smits, Wariya Sanrattana, Nadine D van Kleef, Steven de Maat
Publikováno v: Journal of Thrombosis and Haemostasis. 20:353-365
BACKGROUND Occlusive thrombi are not homogeneous in composition. The core of a thrombus is rich in activated platelets and fibrin while the outer shell contains resting platelets. This core is inaccessible to plasma proteins. We produced a fusion pro
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8e32bbedd19d67c118b81485db1e7cb
https://doi.org/10.1111/jth.15554
Zobrazit plný text záznamu
5
Altered fibrin network structure and fibrinolysis in intensive care unit patients with COVID-19, not entirely explaining the increased risk of thrombosis
Autor: Judith J. de Vries, Chantal Visser, Lotte Geers, Johan A. Slotman, Nadine D. van Kleef, Coen Maas, Hannelore I. Bax, Jelle R. Miedema, Eric C.M. van Gorp, Marco Goeijenbier, Johannes P.C. van den Akker, Henrik Endeman, Dingeman C. Rijken, Marieke J.H.A. Kruip, Moniek P.M. de Maat
Publikováno v: Journal of Thrombosis and Haemostosis, 20(6), 1412-1420. Wiley-Blackwell Publishing Ltd
BACKGROUND: Severe acute respiratory syndrome coronavirus 2 infection is associated with an increased incidence of thrombosis.OBJECTIVES: By studying the fibrin network structure of coronavirus disease 2019 (COVID-19) patients, we aimed to unravel pa
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2a663c64845a86c6d00991b4e2c64ba
https://pubmed.ncbi.nlm.nih.gov/35316570
Zobrazit plný text záznamu
6
VhH anti-thrombomodulin clone 1 inhibits TAFI activation and enhances fibrinolysis in human whole blood under flow
Autor: Marc V.A. van Moorsel, Geke C. Poolen, Cornelis A. Koekman, Sandra Verhoef, Steven de Maat, Arjan Barendrecht, Nadine D. van Kleef, Joost C.M. Meijers, Raymond M. Schiffelers, Coen Maas, Rolf T. Urbanus
Publikováno v: Journal of thrombosis and haemostasis, 20(5), 1213-1222. Wiley-Blackwell
Background: Thrombomodulin on endothelial cells can form a complex with thrombin. This complex has both anticoagulant properties, by activating protein C, and clot-protective properties, by activating thrombin-activatable fibrinolysis inhibitor (TAFI
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::284da5d64712a6b5d5caab023b42e22b
https://pubmed.ncbi.nlm.nih.gov/35170225
Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání

Omezení vyhledávání
Plný text Recenzováno Digitální knihovna AV ČR
Zdroje