Zobrazeno 1 - 10
of 74
pro vyhledávání: '"Nadine Carbuccia"'
Autor:
Renaud Sabatier, Cécile Vicier, Séverine Garnier, Arnaud Guille, Nadine Carbuccia, Nicolas Isambert, Florence Dalenc, Marie Robert, Christelle Levy, Jihane Pakradouni, José Adelaïde, Max Chaffanet, Patrick Sfumato, Emilie Mamessier, François Bertucci, Anthony Goncalves
Publikováno v:
Molecular Oncology, Vol 16, Iss 10, Pp 2057-2070 (2022)
The phosphatidylinositol‐3‐kinase (PI3K)/AKT/mammalian target of rapamycin (mTOR) pathway is frequently activated in HER2‐negative breast cancer and may play a role in taxane resistance. The phase IB/II TAKTIC trial (NCT01980277) has shown that
Externí odkaz:
https://doaj.org/article/703ca5faef324c5b808393f820024f09
Autor:
Renaud Sabatier, Séverine Garnier, Arnaud Guille, Nadine Carbuccia, Jihane Pakradouni, José Adelaide, Magali Provansal, Maria Cappiello, Frédérique Rousseau, Max Chaffanet, Daniel Birnbaum, Emilie Mamessier, Anthony Gonçalves, François Bertucci
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
IntroductionThe poor prognosis of ovarian carcinoma (OvC) is due to the advanced stage at diagnosis, a high risk of relapse after first-line therapies, and the lack of efficient treatments in the recurrence setting. Circulating tumor DNA (ctDNA) anal
Externí odkaz:
https://doaj.org/article/e8ca0d11810341ec999c93a85f969100
Autor:
François Bertucci, Anthony Gonçalves, Arnaud Guille, José Adelaïde, Séverine Garnier, Nadine Carbuccia, Emilien Billon, Pascal Finetti, Patrick Sfumato, Audrey Monneur, Christophe Pécheux, Martin Khran, Serge Brunelle, Lenaïg Mescam, Jeanne Thomassin-Piana, Flora Poizat, Emmanuelle Charafe-Jauffret, Olivier Turrini, Eric Lambaudie, Magali Provansal, Jean-Marc Extra, Anne Madroszyk, Marine Gilabert, Renaud Sabatier, Cécile Vicier, Emilie Mamessier, Christian Chabannon, Jihane Pakradouni, Patrice Viens, Fabrice André, Gwenaelle Gravis, Cornel Popovici, Daniel Birnbaum, Max Chaffanet
Publikováno v:
Genome Medicine, Vol 13, Iss 1, Pp 1-20 (2021)
Abstract Background The benefit of precision medicine based on relatively limited gene sets and often-archived samples remains unproven. PERMED-01 (NCT02342158) was a prospective monocentric clinical trial assessing, in adults with advanced solid can
Externí odkaz:
https://doaj.org/article/685cee8dc4e4477fb464978bcebb91ff
Autor:
François Bertucci, Charlotte Rypens, Pascal Finetti, Arnaud Guille, José Adélaïde, Audrey Monneur, Nadine Carbuccia, Séverine Garnier, Piet Dirix, Anthony Gonçalves, Peter Vermeulen, Bisrat G. Debeb, Xiaoping Wang, Luc Dirix, Naoto T. Ueno, Patrice Viens, Massimo Cristofanilli, Max Chaffanet, Daniel Birnbaum, Steven Van Laere
Publikováno v:
Molecular Oncology, Vol 14, Iss 3, Pp 504-519 (2020)
Inflammatory breast cancer (IBC) is the most pro‐metastatic form of breast cancer. Better understanding of its pathophysiology and identification of actionable genetic alterations (AGAs) are crucial to improve systemic treatment. We aimed to define
Externí odkaz:
https://doaj.org/article/4432b063855f42719a19cc390e05d2c5
Molecular Profiles of Advanced Urological Cancers in the PERMED-01 Precision Medicine Clinical Trial
Autor:
Emilien Billon, Gwenaelle Gravis, Arnaud Guille, Nadine Carbuccia, Jose Adelaide, Séverine Garnier, Pascal Finetti, Emilie Denicolaï, Patrick Sfumato, Serge Brunelle, Jeanne Thomassin-Piana, Géraldine Pignot, Jochen Walz, Christian Chabannon, Jihane Pakradouni, Renaud Sabatier, Cécile Vicier, Cornel Popovici, Emilie Mamessier, Anthony Gonçalves, Daniel Birnbaum, Max Chaffanet, François Bertucci
Publikováno v:
Cancers, Vol 14, Iss 9, p 2275 (2022)
Introduction. The prognosis of advanced urological cancers (AUC) remains unfavorable, and few data are available regarding precision medicine. Methods: the PERMED-01 prospective clinical trial assessed the impact of molecular profiling in adults with
Externí odkaz:
https://doaj.org/article/bc983ea1279a4b5fa1c28af700686434
Autor:
Mathias Neron, Arnaud Guille, Lucie Allegre, Pierre-Emmanuel Colombo, Cristina Leaha, José Adelaide, Nadine Carbuccia, Frédéric Courtier, Florence Boissiere, Evelyne Crapez, Michel Fabbro, Sébastien Gouy, Emilie Mamessier, Éric Lambaudie, Daniel Birnbaum, François Bertucci, Max Chaffanet
Publikováno v:
Journal of Personalized Medicine, Vol 12, Iss 5, p 655 (2022)
Hormone therapy (HT) is an effective treatment for metastatic endometrial carcinoma (mEC), with limited toxicity and low cost. We focused on molecular analysis of mECs treated by HT and, for the first time to date, we compared the genomic profiles of
Externí odkaz:
https://doaj.org/article/87d4b66218ef44828424bd5be606b396
Autor:
Frédéric Courtier, Nadine Carbuccia, Séverine Garnier, Arnaud Guille, José Adélaïde, Nathalie Cervera, Véronique Gelsi-Boyer, Marie-Joelle Mozziconacci, Jérôme Rey, Norbert Vey, Max Chaffanet, Daniel Birnbaum, Anne Murati
Publikováno v:
Haematologica, Vol 102, Iss 1 (2017)
Externí odkaz:
https://doaj.org/article/71456fbe61dd4648a3f7605400fc1cdb
Autor:
Marguerite Tyran, Nadine Carbuccia, Séverine Garnier, Arnaud Guille, José Adelaïde, Pascal Finetti, Julien Toulzian, Patrice Viens, Agnès Tallet, Anthony Goncalves, Philippe Metellus, Daniel Birnbaum, Max Chaffanet, François Bertucci
Publikováno v:
Cancers, Vol 11, Iss 5, p 665 (2019)
Improving the systemic treatment of brain metastases (BM) in primary breast cancer (PBC) is impaired by the lack of genomic characterization of BM. To estimate the concordance of DNA copy-number-alterations (CNAs), mutations, and actionable genetic a
Externí odkaz:
https://doaj.org/article/aecb411ce7d24b019a089cf150b24bb0
Autor:
Stéphanie Cornen, Arnaud Guille, José Adélaïde, Lynda Addou-Klouche, Pascal Finetti, Marie-Rose Saade, Marwa Manai, Nadine Carbuccia, Ismahane Bekhouche, Anne Letessier, Stéphane Raynaud, Emmanuelle Charafe-Jauffret, Jocelyne Jacquemier, Salvatore Spicuglia, Hugues de The, Patrice Viens, François Bertucci, Daniel Birnbaum, Max Chaffanet
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e81843 (2014)
Breast cancers (BCs) of the luminal B subtype are estrogen receptor-positive (ER+), highly proliferative, resistant to standard therapies and have a poor prognosis. To better understand this subtype we compared DNA copy number aberrations (CNAs), DNA
Externí odkaz:
https://doaj.org/article/dd7de6bb6d7f4633bb855660fd9edec5
Autor:
Marc Lopez, François Bertucci, Daniel Birnbaum, Emilie Mamessier, Emmanuelle Charafe-Jauffret, Anthony Gonçalves, Max Chaffanet, Emilie Agavnian, Anne Farina, Nadine Carbuccia, Arnaud Guille, Sèverine Garnier, Pascal Finetti, José Adélaide, Emerence Crompot, Ludovic Berger, Olivier Cabaud
Supplementary Figure from Overcoming Resistance to Anti–Nectin-4 Antibody-Drug Conjugate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bcec6c70e62d58c92f36ed64744fda8
https://doi.org/10.1158/1535-7163.22522941.v1
https://doi.org/10.1158/1535-7163.22522941.v1