Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Nadine Biesemann"'
Autor:
Lingzi Li, Janina Freitag, Christian Asbrand, Bogdan Munteanu, Bei-Tzu Wang, Ekaterina Zezina, Michel Didier, Gilbert Thill, Corinne Rocher, Matthias Herrmann, Nadine Biesemann
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-20 (2022)
Abstract Rheumatoid arthritis (RA) is characterized by joint infiltration of immune cells and synovial inflammation which leads to progressive disability. Current treatments improve the disease outcome, but the unmet medical need is still high. New d
Externí odkaz:
https://doaj.org/article/5ab8fa376cd44e9c93d89d8361b62c7d
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract TNF is a central cytokine in the pathogenesis of rheumatoid arthritis (RA). Elevated level of TNF causes local inflammation that affects immune cells and fibroblast-like synoviocytes (FLS). Nowadays, only 20–30% of patients experience remi
Externí odkaz:
https://doaj.org/article/695dcc322f0344b397d04593c01b217c
Autor:
Nadine Biesemann, Daniel Margerie, Christian Asbrand, Markus Rehberg, Virginia Savova, Inoncent Agueusop, Daniel Klemmer, Danping Ding-Pfennigdorff, Uwe Schwahn, Markus Dudek, Karen Heyninck, Evelyn De Tavernier, Sigrid Cornelis, Markus Kohlmann, Frank O. Nestle, Matthias Herrmann
Publikováno v:
Science Translational Medicine. 15
Rheumatoid arthritis (RA) is one of the most common autoimmune diseases affecting primarily the joints. Despite successful therapies including antibodies against tumor necrosis factor (TNF) and interleukin-6 (IL-6) receptor, only 20 to 30% of patient
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::29743386b5e3350b792b9d00fe3f309c
https://doi.org/10.1126/scitranslmed.abq4419
https://doi.org/10.1126/scitranslmed.abq4419
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Scientific Reports
Scientific Reports
TNF is a central cytokine in the pathogenesis of rheumatoid arthritis (RA). Elevated level of TNF causes local inflammation that affects immune cells and fibroblast-like synoviocytes (FLS). Nowadays, only 20–30% of patients experience remission aft
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f64ed06b88d8684ea6865420a08d1d4
https://doaj.org/article/695dcc322f0344b397d04593c01b217c
https://doaj.org/article/695dcc322f0344b397d04593c01b217c
Publikováno v:
WIREs Systems Biology and Medicine. 12
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cbcbc1695aa277bdd1147e3f08c05ebf
https://doi.org/10.1002/wsbm.1498
https://doi.org/10.1002/wsbm.1498
Publikováno v:
WIREs Systems Biology and Medicine. 12
Knowledge about metabolism of immune cells increased almost exponentially during the last two decades and thereby created the new area immunometabolism. Increased glucose uptake and glycolysis were identified as one of the major drivers in immune cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b437c12ea06383a3f1768d79637db0d5
https://doi.org/10.1002/wsbm.1483
https://doi.org/10.1002/wsbm.1483
Autor:
Wolfgang Hennerici, Thomas Leeuw, Axel Dietrich, Christian Asbrand, Janina S. Ried, Nadine Biesemann, Danping Ding-Pfennigdorff, Steffen Hahn, Christine Rudolph, Carsten Strübing
Publikováno v:
Scientific Reports
Scientific Reports, Vol 8, Iss 1, Pp 1-12 (2018)
Scientific Reports, Vol 8, Iss 1, Pp 1-12 (2018)
Mitochondrial dysfunction is increasingly recognized as a contributor to age-related muscle loss and functional impairment. Therefore, we developed a high throughput screening strategy that enabled the identification of compounds boosting mitochondri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2125f3bb7a93f5c702e76e8242618d0a
https://doi.org/10.1038/s41598-018-27614-8
https://doi.org/10.1038/s41598-018-27614-8
Autor:
Luca Mendler, Michael Schäfers, Thilo Borchardt, Sven Hermann, Thomas Braun, Marcus Krüger, Thomas Boettger, Nadine Biesemann, Astrid Wietelmann
Publikováno v:
Circulation Research. 115:296-310
Rationale : Myostatin is a major negative regulator of skeletal muscle mass and initiates multiple metabolic changes, including enhanced insulin sensitivity. However, the function of myostatin in the heart is barely understood, although it is upregul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::42cbd8aa2769341eadcddcd6b88783e6
https://doi.org/10.1161/circresaha.115.304185
https://doi.org/10.1161/circresaha.115.304185
Autor:
Thomas Braun, Nadine Biesemann
Publikováno v:
Circulation research. 116(10)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f30f407c5b155b06afdd429ddf08c1c4
https://pubmed.ncbi.nlm.nih.gov/25953927
https://pubmed.ncbi.nlm.nih.gov/25953927
Autor:
Thomas Braun, Nadine Biesemann
Publikováno v:
Circulation research. 116(7)
In the article1 referred to in Drs McLean and Oudit’s letter,2 we ana lyzed the effects of inactivation of myostatin in adult cardiomyocytes. Drs McLean and Oudit correctly point out that treatment of mice with tamoxifen to induce activation of cre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::feaef6a6bc7bb9688beea83a2a09408e
https://pubmed.ncbi.nlm.nih.gov/25814688
https://pubmed.ncbi.nlm.nih.gov/25814688