Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Nadine Aubin"'
Autor:
Tuan-Minh Do, Cécile Capdevila, Laurent Pradier, Véronique Blanchard, Mati Lopez-Grancha, Nathalie Schussler, Anke Steinmetz, Jochen Beninga, Denis Boulay, Philippe Dugay, Patrick Verdier, Nadine Aubin, Gihad Dargazanli, Catarina Chaves, Elisabeth Genet, Yves Lossouarn, Christophe Loux, François Michoux, Nicolas Moindrot, Franck Chanut, Thierry Gury, Stéphanie Eyquem, Delphine Valente, Olivier Bergis, Ercole Rao, Dominique Lesuisse
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 19, Iss , Pp 58-77 (2020)
Most antibodies display very low brain exposure due to the blood-brain barrier (BBB) preventing their entry into brain parenchyma. Transferrin receptor (TfR) has been used previously to ferry antibodies to the brain by using different formats of bisp
Externí odkaz:
https://doaj.org/article/83381acf39a84e849321af0a96b558c0
Autor:
Patrick Verdier, Stéphanie Eyquem, François Michoux, Véronique Blanchard, Dominique Lesuisse, Philippe Dugay, Thierry Gury, Olivier Bergis, Tuan Minh Do, Jochen Beninga, Nadine Aubin, Denis Boulay, Christophe Loux, Mati Lopez-Grancha, Catarina Chaves, Nicolas Moindrot, Delphine Valente, Cécile Capdevila, Nathalie Schussler, Ercole Rao, Gihad Dargazanli, Laurent Pradier, Yves Lossouarn, Franck Chanut, Elisabeth Genet, Anke Steinmetz
Publikováno v:
Molecular Therapy. Methods & Clinical Development
Molecular Therapy: Methods & Clinical Development, Vol 19, Iss, Pp 58-77 (2020)
Molecular Therapy: Methods & Clinical Development, Vol 19, Iss, Pp 58-77 (2020)
Most antibodies display very low brain exposure due to the blood-brain barrier (BBB) preventing their entry into brain parenchyma. Transferrin receptor (TfR) has been used previously to ferry antibodies to the brain by using different formats of bisp
Publikováno v:
ResearcherID
The neurotoxic effects of the dopamine-selective neurotoxin MPTP (15 mg/kg, s.c.), in mice, were totally prevented by systemic administration of salicylate (ED50 = 40 mg/kg, i.p.), aspirin (ED50 = 60 mg/kg, i.p.), or the soluble lysine salt of aspiri
Publikováno v:
European Journal of Neuroscience. 12:322-336
We have examined the behavioural consequences of a partial unilateral dopaminergic denervation of the rat striatum. This partial lesion was obtained by an intrastriatal 6-hydroxy-dopamine injection (6-OHDA, 20 or 10 microgram divided between two inje