Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Nadine Müther"'
Autor:
Wenli Zhang, Manish Solanki, Nadine Müther, Melanie Ebel, Jichang Wang, Chuanbo Sun, Zsuzsanna Izsvak, Anja Ehrhardt
Publikováno v:
PLoS ONE, Vol 15, Iss 1, p e0228707 (2020)
[This corrects the article DOI: 10.1371/journal.pone.0076771.].
Externí odkaz:
https://doaj.org/article/ae9afc0814a74c28b0f4b8260e097a96
Publikováno v:
Viruses, Vol 1, Iss 3, Pp 1295-1324 (2009)
The turbulent history of clinical trials in viral gene therapy has taught us important lessons about vector design and safety issues. Much effort was spent on analyzing genotoxicity after somatic integration of therapeutic DNA into the host genome. B
Externí odkaz:
https://doaj.org/article/09eebabbd66f4d28bd4c4c756506b2c8
Autor:
Wenli Zhang, Manish Solanki, Nadine Müther, Melanie Ebel, Jichang Wang, Chuanbo Sun, Zsuzsanna Izsvak, Anja Ehrhardt
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e76771 (2013)
Recombinant adeno-associated viral (AAV) vectors have been shown to be one of the most promising vectors for therapeutic gene delivery because they can induce efficient and long-term transduction in non-dividing cells with negligible side-effects. Ho
Externí odkaz:
https://doaj.org/article/2fc78863c15846098c412caf9acb44e4
Autor:
Michaela Nygårdas, Henrik Paavilainen, Nadine Müther, Claus-Henning Nagel, Matias Röyttä, Beate Sodeik, Veijo Hukkanen
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e64200 (2013)
Herpes simplex virus type 1 (HSV-1) has properties that can be exploited for the development of gene therapy vectors. The neurotropism of HSV enables delivery of therapeutic genes to the nervous system. Using a bacterial artificial chromosome (BAC),
Externí odkaz:
https://doaj.org/article/f68e157352fd47a3830a6bacbd134747
Autor:
Wenli Zhang, Manish Solanki, Nadine Müther, Melanie Ebel, Jichang Wang, Chuanbo Sun, Zsuzsanna Izsvak, Anja Ehrhardt
Publikováno v:
PLoS ONE, Vol 8, Iss 11 (2013)
Externí odkaz:
https://doaj.org/article/2622cc1e0ff7401ea0df6330c89e97eb
Autor:
Anja Ehrhardt, Christina Rauschhuber, Nadine Müther, Wenli Zhang, Martin Hausl, Richard Voigtlander
Publikováno v:
Current Gene Therapy. 11:363-374
The Sleeping Beauty (SB) transposase system for somatic integration offers great potential for in vivo gene therapeutic applications and genome engineering. Until recently, however, efficacy of SB transposase as a gene transfer vector especially in l
Publikováno v:
Viruses
Viruses, Vol 1, Iss 3, Pp 1295-1324 (2009)
Viruses, Vol 1, Iss 3, Pp 1295-1324 (2009)
The turbulent history of clinical trials in viral gene therapy has taught us important lessons about vector design and safety issues. Much effort was spent on analyzing genotoxicity after somatic integration of therapeutic DNA into the host genome. B
Autor:
Henrike Caysa, Martin Messerle, Roland Jacob, Bruce R. Branchini, Nadine Müther, Ariane Söling
Publikováno v:
Photochemical & Photobiological Sciences. 8:52-56
Bioluminescence imaging has evolved as a powerful tool for monitoring biological processes in vivo. As transmission efficiency of light through tissue increases greatly for wavelengths above 600 nm we examined whether a redshifted codon-optimized fir
Autor:
Beate Sodeik, Matias Röyttä, Henrik Paavilainen, Nadine Müther, Claus-Henning Nagel, Veijo Hukkanen, Michaela Nygårdas
Publikováno v:
PLoS ONE
PLoS ONE, Vol 8, Iss 5, p e64200 (2013)
PLoS ONE, Vol 8, Iss 5, p e64200 (2013)
Herpes simplex virus type 1 (HSV-1) has properties that can be exploited for the development of gene therapy vectors. The neurotropism of HSV enables delivery of therapeutic genes to the nervous system. Using a bacterial artificial chromosome (BAC),