Zobrazeno 1 - 10
of 145
pro vyhledávání: '"Nadine, Norton"'
Autor:
Katelyn A. Bruno, Walter G. O'Dell, Marwa Tantawy, Camara L. Casson, Meghan C. Ferrall-Fairbanks, David L. DeRemer, Jennifer R. Dungan, Branden L. Nguyen, Nathalie H. Roumi, Samia Shabnaz, Ashley J. Smuder, Melissa J. Vilaro, Nadine Norton, DeLisa Fairweather, Yan Gong
Publikováno v:
American Heart Journal Plus, Vol 37, Iss , Pp 100348- (2024)
Externí odkaz:
https://doaj.org/article/cf96ad2da7864901b0feb6ce3dbc6fea
Autor:
Pooja P. Advani, Kathryn J. Ruddy, Joerg Herrmann, Jordan C. Ray, Emily C. Craver, Greg Yothers, Reena S. Cecchini, Corey Lipchik, Huichen Feng, Priya Rastogi, Eleftherios P. Mamounas, Sandra M. Swain, Charles E. Geyer, Norman Wolmark, Soonmyung Paik, Katherine L. Pogue-Geile, Gerardo Colon-Otero, Edith A. Perez, Nadine Norton
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
BackgroundThe cardiotoxic effects of doxorubicin, trastuzumab, and other anticancer agents are well known, but molecular genetic testing is lacking for the early identification of patients at risk for therapy-related cardiac toxicity.MethodsUsing the
Externí odkaz:
https://doaj.org/article/0bd121bdd57c4d5fb05b24d6e6c5fc77
Autor:
Saranya Chumsri, Zhuo Li, Daniel J. Serie, Nadine Norton, Afshin Mashadi-Hossein, Kathleen Tenner, Heather Ann Brauer, Sarah Warren, Patrick Danaher, Gerardo Colon-Otero, Ann H. Partridge, Lisa A. Carey, Florentine Hilbers, Veerle Van Dooren, Eileen Holmes, Serena Di Cosimo, Olena Werner, Jens Bodo Huober, Amylou C. Dueck, Christos Sotiriou, Cristina Saura, Alvaro Moreno-Aspitia, Keith L. Knutson, Edith A. Perez, E. Aubrey Thompson
Publikováno v:
npj Breast Cancer, Vol 8, Iss 1, Pp 1-8 (2022)
Abstract Trastuzumab acts in part through the adaptive immune system. Previous studies showed that enrichment of immune-related gene expression was associated with improved outcomes in HER2-positive (HER2+) breast cancer. However, the role of the imm
Externí odkaz:
https://doaj.org/article/c541e25cb1954a448e8d1d99ad81395d
Autor:
Nadine Norton, Katelyn A. Bruno, Damian N. Di Florio, Emily R. Whelan, Anneliese R. Hill, Andrea Carolina Morales-Lara, Anna A. Mease, John M. Sousou, Jose A. Malavet, Lauren E. Dorn, Gary R. Salomon, Logan P. Macomb, Sami Khatib, Zacharias P. Anastasiadis, Brian M. Necela, Molly M. McGuire, Presley G. Giresi, Archana Kotha, Danielle J. Beetler, Raegan M. Weil, Carolyn K. Landolfo, DeLisa Fairweather
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 8 (2022)
Background: Doxorubicin is a widely used and effective chemotherapy, but the major limiting side effect is cardiomyopathy which in some patients leads to congestive heart failure. Genetic variants in TRPC6 have been associated with the development of
Externí odkaz:
https://doaj.org/article/85bee347666346f7a718979912b458e6
Autor:
Saranya Chumsri, Zhuo Li, Nadine Norton, Alvaro Moreno-Aspitia, Gerardo Colon-Otero, Keith L. Knutson, Antonio C. Wolff, Edith A. Perez, E. A. Thompson
Publikováno v:
Cancer Research. 83:P2-11
Background: We previously demonstrated that intrinsic subtypes were associated with prognosis for early recurrence risk in patients (pts) with early-stage HER2-positive (HER2+) BC treated with trastuzumab (H) in the N9831 trial. Here, we evaluated th
Autor:
Nadine Norton, Julia E. Crook, Liwei Wang, Janet E. Olson, Jennifer M. Kachergus, Daniel J. Serie, Brian M. Necela, Paul G. Borgman, Pooja P. Advani, Jordan C. Ray, Carolyn Landolfo, Damian N. Di Florio, Anneliese R. Hill, Katelyn A. Bruno, DeLisa Fairweather
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 7 (2020)
Background: Our previous GWAS identified genetic variants at six novel loci that were associated with a decline in left ventricular ejection fraction (LVEF), p < 1 × 10−5 in 1,191 early breast cancer patients from the N9831 clinical trial of chemo
Externí odkaz:
https://doaj.org/article/922e44420c164389a361f750d52e32b3
Autor:
Nadine Norton, Nicholas Fox, Christie-Ann McCarl, Kathleen S. Tenner, Karla Ballman, Courtney L. Erskine, Brian M. Necela, Donald Northfelt, Winston W. Tan, Carmen Calfa, Mark Pegram, Gerardo Colon-Otero, Edith A. Perez, Raphael Clynes, Keith L. Knutson
Publikováno v:
Breast Cancer Research, Vol 20, Iss 1, Pp 1-9 (2018)
Abstract Background Resected HER2 breast cancer patients treated with adjuvant trastuzumab and chemotherapy have superior survival compared to patients treated with chemotherapy alone. We previously showed that trastuzumab and chemotherapy induce HER
Externí odkaz:
https://doaj.org/article/1c1febf941ce45ac8dcb2e8d12e66fb8
Publikováno v:
Journal of Clinical Medicine, Vol 10, Iss 18, p 4079 (2021)
Anthracyclines are one of the most widely used and effective chemotherapies in oncology, but their most important side effect is the cumulative, dose-related cardiotoxicity leading to congestive heart failure in ~5% of individuals. Methodology and ph
Externí odkaz:
https://doaj.org/article/51b1349cc79143a19047b09d01f954cc
Autor:
Edith A. Perez, Keith L. Knutson, Raphael Clynes, Karla V. Ballman, Kathleen Tenner, Mark Pegram, Rebecca M. Olson, Nadine Norton
Supplementary Table S1. Patient characteristics genotyped cohort vs non-genotyped cohort. Supplementary Table S2. Patient characteristics according to FCGR3A genotype. Supplementary Table S3. Patient characteristics according to FCGR2A genotype. Supp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::046041a0da5a33d146faaf892f6beda8
https://doi.org/10.1158/2326-6066.22536017.v1
https://doi.org/10.1158/2326-6066.22536017.v1
Autor:
Edith A. Perez, Keith L. Knutson, Raphael Clynes, Karla V. Ballman, Kathleen Tenner, Mark Pegram, Rebecca M. Olson, Nadine Norton
Patients with HER2+ breast cancer treated with trastuzumab and chemotherapy have superior survival compared with patients treated with chemotherapy alone. Polymorphisms within FCGR2A and FCGR3A are associated with binding affinity of natural killer c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f0accaa84ccd6decc170a50ab298ae2e
https://doi.org/10.1158/2326-6066.c.6548018.v1
https://doi.org/10.1158/2326-6066.c.6548018.v1