Zobrazeno 1 - 10
of 121
pro vyhledávání: '"Nadine, Darwiche"'
Publikováno v:
Nanomaterials, Vol 14, Iss 17, p 1380 (2024)
Cancer is a major public health problem that ranks as the second leading cause of death. Anti-cancer drug development presents with various hurdles faced throughout the process. Nanoparticle (NP) formulations have emerged as a promising strategy for
Externí odkaz:
https://doaj.org/article/8194ebef020c43dc956f7cbfdb6cb2fb
Publikováno v:
Nutrients, Vol 16, Iss 7, p 1095 (2024)
Research has identified both nonmodifiable and modifiable risk factors for breast cancer (BC), with accumulating evidence showing that adopting adequate dietary practices could decrease the risk of this disease. This study aimed to assess nutrition k
Externí odkaz:
https://doaj.org/article/02c65e2c8afb401ebf914f0cc22ba040
Autor:
Reem Halabi, Fatima Dakroub, Mohammad Z. Haider, Stuti Patel, Nayef A. Amhaz, Mohammad A. Reslan, Ali H. Eid, Yehia Mechref, Nadine Darwiche, Firas Kobeissy, Ibrahim Omeis, Abdullah A. Shaito
Publikováno v:
Cancers, Vol 15, Iss 22, p 5339 (2023)
Meningiomas are the most prevalent primary intracranial tumors. The majority are benign but can undergo dedifferentiation into advanced grades classified by World Health Organization (WHO) into Grades 1 to 3. Meningiomas’ tremendous variability in
Externí odkaz:
https://doaj.org/article/01c46df6835844f99bfa7f340860d8a5
Autor:
Chirine El-Baba, Zeinab Ayache, Mona Goli, Berthe Hayar, Zeinab Kawtharani, Claudio Pisano, Firas Kobeissy, Yehia Mechref, Nadine Darwiche
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 18, p 14069 (2023)
Glioblastoma Multiforme (GBM) is the most aggressive form of malignant brain tumor. The median survival rate does not exceed two years, indicating an imminent need to develop novel therapies. The atypical adamantyl retinoid ST1926 induces apoptosis a
Externí odkaz:
https://doaj.org/article/03a89d806e12445f97ed25d2e29771b2
Publikováno v:
Current Drug Delivery. 20:1314-1326
Abstract: Retinoids represent a class of chemical compounds derived from or structurally and functionally related to vitamin A. Retinoids play crucial roles in regulating a range of crucial biological processes spanning embryonic development to adult
Autor:
Sadaf Al Hadeethi, Chirine El-Baba, Khaled Araji, Berthe Hayar, Israa Ahmad Cheikh, Riyad El-Khoury, Julnar Usta, Nadine Darwiche
Publikováno v:
Cancers, Vol 15, Iss 8, p 2268 (2023)
Colorectal cancer (CRC) is one of the leading cancers and causes of death in patients. 5-fluorouracil (5-FU) is the therapy of choice for CRC, but it exhibits high toxicity and drug resistance. Tumorigenesis is characterized by a deregulated metaboli
Externí odkaz:
https://doaj.org/article/1921a167c778470f8c152d8817f66aa4
Autor:
Ibrahim AlZaim, Aya Al-Saidi, Safaa H. Hammoud, Nadine Darwiche, Yusra Al-Dhaheri, Ali H. Eid, Ahmed F. El-Yazbi
Publikováno v:
Cancers, Vol 14, Iss 7, p 1679 (2022)
The increased global prevalence of metabolic disorders including obesity, insulin resistance, metabolic syndrome and diabetes is mirrored by an increased incidence of prostate cancer (PCa). Ample evidence suggests that these metabolic disorders, bein
Externí odkaz:
https://doaj.org/article/4fc051249d7c4d09ab7c22af7c7140fb
Autor:
Samar Khalil, Tara Bardawil, Carla Stephan, Nadine Darwiche, Ossama Abbas, Abdul Ghani Kibbi, Georges Nemer, Mazen Kurban
Publikováno v:
Journal of Dermatological Treatment, Vol 28, Iss 8, Pp 684-696 (2017)
Retinoids are a class of compounds derived from vitamin A or having structural and/or functional similarities with vitamin A. They are classified into three generations based on their molecular structures. Inside the body, retinoids bind to several c
Externí odkaz:
https://doaj.org/article/5cb1987c93374a6f8cee84471996a5f5
Autor:
Lamis Al Aaraj, Berthe Hayar, Zaynab Jaber, Walid Saad, Najat A. Saliba, Nadine Darwiche, Tarek Ghaddar
Publikováno v:
Molecules, Vol 26, Iss 18, p 5481 (2021)
Several sesquiterpene lactones (STLs) have been tested as lead drugs in cancer clinical trials. Salograviolide-A (Sal-A) and salograviolide-B (Sal-B) are two STLs that have been isolated from Centaurea ainetensis, an indigenous medicinal plant of the
Externí odkaz:
https://doaj.org/article/fd9c85d9e408474d90efc6d0d685a41f
Autor:
Humam Kadara, Avrum E. Spira, Junya Fujimoto, Paul Scheet, Ignacio I. Wistuba, Arafat Tfayli, Hassan Chami, Nadine Darwiche, Georges Nemer, Junya Fukuoka, Sayuri Nunomura-Nakamura, Wenhua Lang, Smruthy Sivakumar, Tina L. McDowell, Li Xu, Ansam Sinjab, Jacob Kantrowitz
Smoking perpetuates in cytologically normal airways a molecular “field of injury” that is pertinent to lung cancer and early detection. The evolution of airway field changes prior to lung oncogenesis is poorly understood largely due to the long l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e17e9900f6b54bea4f91e241866843c
https://doi.org/10.1158/1940-6207.c.6547019
https://doi.org/10.1158/1940-6207.c.6547019