Zobrazeno 1 - 10
of 174
pro vyhledávání: '"Nadine, Darwiche"'
Publikováno v:
Nanomaterials, Vol 14, Iss 17, p 1380 (2024)
Cancer is a major public health problem that ranks as the second leading cause of death. Anti-cancer drug development presents with various hurdles faced throughout the process. Nanoparticle (NP) formulations have emerged as a promising strategy for
Externí odkaz:
https://doaj.org/article/8194ebef020c43dc956f7cbfdb6cb2fb
Publikováno v:
Nutrients, Vol 16, Iss 7, p 1095 (2024)
Research has identified both nonmodifiable and modifiable risk factors for breast cancer (BC), with accumulating evidence showing that adopting adequate dietary practices could decrease the risk of this disease. This study aimed to assess nutrition k
Externí odkaz:
https://doaj.org/article/02c65e2c8afb401ebf914f0cc22ba040
Autor:
Chirine El-Baba, Zeinab Ayache, Mona Goli, Berthe Hayar, Zeinab Kawtharani, Claudio Pisano, Firas Kobeissy, Yehia Mechref, Nadine Darwiche
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 18, p 14069 (2023)
Glioblastoma Multiforme (GBM) is the most aggressive form of malignant brain tumor. The median survival rate does not exceed two years, indicating an imminent need to develop novel therapies. The atypical adamantyl retinoid ST1926 induces apoptosis a
Externí odkaz:
https://doaj.org/article/03a89d806e12445f97ed25d2e29771b2
Publikováno v:
Current Drug Delivery. 20:1314-1326
Abstract: Retinoids represent a class of chemical compounds derived from or structurally and functionally related to vitamin A. Retinoids play crucial roles in regulating a range of crucial biological processes spanning embryonic development to adult
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a4245f458d0139d558da3c017e076b2
https://doi.org/10.2174/1567201819666220810094708
https://doi.org/10.2174/1567201819666220810094708
Autor:
Lamis Al Aaraj, Berthe Hayar, Zaynab Jaber, Walid Saad, Najat A. Saliba, Nadine Darwiche, Tarek Ghaddar
Publikováno v:
Molecules, Vol 26, Iss 18, p 5481 (2021)
Several sesquiterpene lactones (STLs) have been tested as lead drugs in cancer clinical trials. Salograviolide-A (Sal-A) and salograviolide-B (Sal-B) are two STLs that have been isolated from Centaurea ainetensis, an indigenous medicinal plant of the
Externí odkaz:
https://doaj.org/article/fd9c85d9e408474d90efc6d0d685a41f
Autor:
Humam Kadara, Avrum E. Spira, Junya Fujimoto, Paul Scheet, Ignacio I. Wistuba, Arafat Tfayli, Hassan Chami, Nadine Darwiche, Georges Nemer, Junya Fukuoka, Sayuri Nunomura-Nakamura, Wenhua Lang, Smruthy Sivakumar, Tina L. McDowell, Li Xu, Ansam Sinjab, Jacob Kantrowitz
Smoking perpetuates in cytologically normal airways a molecular “field of injury” that is pertinent to lung cancer and early detection. The evolution of airway field changes prior to lung oncogenesis is poorly understood largely due to the long l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e17e9900f6b54bea4f91e241866843c
https://doi.org/10.1158/1940-6207.c.6547019
https://doi.org/10.1158/1940-6207.c.6547019
Autor:
Nadine Darwiche, Regine Schneider-Stock, Hala Gali-Muhtasib, Tilman Rau, Melody Saikali, Akram Ghantous
PDF file - 150K, Parthenolide causes HDAC1 cleavage without altering global HDAC activity and histone acetylation and methylation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b6adb212b874f7bcdef198ffbfa9b62
https://doi.org/10.1158/1940-6207.22525058.v1
https://doi.org/10.1158/1940-6207.22525058.v1
Autor:
Nadine Darwiche, Hiba El Hajj, Claudio Pisano, Angelo Mancinelli, Maguy Hamie, Rita Hleihel, Rana Abdel-Samad, Nadim Tawil, Patrick Aouad, Berthe Hayar, Walid Saad, Leeanna El-Houjeiri
Acute myeloid leukemia (AML) is one of the most frequent types of blood malignancies. It is a complex disorder of undifferentiated hematopoietic progenitor cells. The majority of patients generally respond to intensive therapy. Nevertheless, relapse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4ad82201abdefdaa82770540556c3844
https://doi.org/10.1158/1535-7163.c.6538707.v1
https://doi.org/10.1158/1535-7163.c.6538707.v1
Autor:
Nadine Darwiche, Regine Schneider-Stock, Hala Gali-Muhtasib, Tilman Rau, Melody Saikali, Akram Ghantous
PDF file - 149K, Parthenolide inhibits NF-�B DNA binding affinity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b3b50ff46a56386b9514f1f5b698aaa
https://doi.org/10.1158/1940-6207.22525061
https://doi.org/10.1158/1940-6207.22525061
Autor:
Humam Kadara, Avrum E. Spira, Junya Fujimoto, Paul Scheet, Ignacio I. Wistuba, Arafat Tfayli, Hassan Chami, Nadine Darwiche, Georges Nemer, Junya Fukuoka, Sayuri Nunomura-Nakamura, Wenhua Lang, Smruthy Sivakumar, Tina L. McDowell, Li Xu, Ansam Sinjab, Jacob Kantrowitz
Supplementary Tables Table S1. Early efffcts of NNK exposure on the mouse airway transcriptome. Table S2. Evolutionarily conserved decreased gene expression in the airway following NNK exposure. Table S3. Genes differentially regulated in the mouse a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10f23225b5af3e7710a7aeda36e67677
https://doi.org/10.1158/1940-6207.22533305.v1
https://doi.org/10.1158/1940-6207.22533305.v1