Zobrazeno 1 - 10
of 113
pro vyhledávání: '"Nadine, Colpo"'
Autor:
Lei Wang, Hsiou-Ting Kuo, Zhengxing Zhang, Chengcheng Zhang, Chao-Cheng Chen, Devon Chapple, Ryan Wilson, Nadine Colpo, François Bénard, Kuo-Shyan Lin
Publikováno v:
EJNMMI Radiopharmacy and Chemistry, Vol 9, Iss 1, Pp 1-15 (2024)
Abstract Background Overexpressed in various solid tumors, gastrin-releasing peptide receptor (GRPR) is a promising cancer imaging marker and therapeutic target. Although antagonists are preferable for the development of GRPR-targeted radiopharmaceut
Externí odkaz:
https://doaj.org/article/24ff8b25475b4173968a9c483ac5e550
Autor:
Marin Simunic, Jay T. Joshi, Helen Merkens, Nadine Colpo, Hsiou-Ting Kuo, Julian J. Lum, François Bénard
Publikováno v:
EJNMMI Research, Vol 14, Iss 1, Pp 1-7 (2024)
Externí odkaz:
https://doaj.org/article/d7a3c8e0d16a4df99867cf7dee5f8f2d
Autor:
Lei Wang, Hsiou-Ting Kuo, Chao-Cheng Chen, Devon Chapple, Nadine Colpo, Pauline Ng, Wing Sum Lau, Shireen Jozi, François Bénard, Kuo-Shyan Lin
Publikováno v:
Molecules, Vol 29, Iss 13, p 3102 (2024)
Gastrin-releasing peptide receptor (GRPR), overexpressed in many solid tumors, is a promising imaging marker and therapeutic target. Most reported GRPR-targeted radioligands contain a C-terminal amide. Based on the reported potent antagonist D-Phe-Gl
Externí odkaz:
https://doaj.org/article/90a3007f690d4f83bd84d2472d76249b
Autor:
Lei Wang, Chao-Cheng Chen, Zhengxing Zhang, Hsiou-Ting Kuo, Chengcheng Zhang, Nadine Colpo, Helen Merkens, François Bénard, Kuo-Shyan Lin
Publikováno v:
Pharmaceuticals, Vol 17, Iss 5, p 621 (2024)
Gastrin-releasing peptide receptor (GRPR) is overexpressed in various cancers and is a promising target for cancer diagnosis and therapy. However, the high pancreas uptake and/or metabolic instability observed for most reported GRPR-targeted radiolig
Externí odkaz:
https://doaj.org/article/16c02e200e2b477db4930b5913cbb995
Autor:
Kelly Lu, Chengcheng Zhang, Zhengxing Zhang, Hsiou-Ting Kuo, Nadine Colpo, François Bénard, Kuo-Shyan Lin
Publikováno v:
Molecules, Vol 28, Iss 13, p 5120 (2023)
Prostate-specific membrane antigen (PSMA) is a well-validated prostate cancer marker but reported PSMA-targeted tracers derived from the Lys-urea-Glu pharmacophore including the clinically validated [99mTc]Tc-EDDA/HYNIC-iPSMA have high off-target upt
Externí odkaz:
https://doaj.org/article/a23a92c7c4be45ef9200f20f8fc7bf64
Autor:
Shreya Bendre, Zhengxing Zhang, Nadine Colpo, Jutta Zeisler, Antonio A. W. L. Wong, François Bénard, Kuo-Shyan Lin
Publikováno v:
Molecules, Vol 28, Iss 8, p 3481 (2023)
Fibroblast activation protein α (FAP-α) is a cell-surface protein overexpressed on cancer-associated fibroblasts that constitute a substantial component of tumor stroma and drive tumorigenesis. FAP is minimally expressed by most healthy tissues, in
Externí odkaz:
https://doaj.org/article/5a8504142a36492583ea20465ed91249
Autor:
Chengcheng Zhang, Zhengxing Zhang, Jutta Zeisler, Nadine Colpo, Kuo-Shyan Lin, François Bénard
Publikováno v:
ACS Omega, Vol 5, Iss 19, Pp 10767-10773 (2020)
Externí odkaz:
https://doaj.org/article/85bcbb1c97e843bf9dbcd975977736ee
Autor:
Iulia Dude, Zhengxing Zhang, Julie Rousseau, Navjit Hundal-Jabal, Nadine Colpo, Helen Merkens, Kuo-Shyan Lin, François Bénard
Publikováno v:
EJNMMI Radiopharmacy and Chemistry, Vol 2, Iss 1, Pp 1-16 (2017)
Abstract Background The somatostatin receptor subtype 2 (sstr2) is expressed on a majority of luminal breast cancers, however SPECT and scintigraphy imaging with agonistic sstr2 probes has been sub-optimal. High affinity antagonists can access more b
Externí odkaz:
https://doaj.org/article/f25e1f45ad284796aa44ebc8feb5be0a
Autor:
Zhengxing Zhang, Joseph Lau, Chengcheng Zhang, Nadine Colpo, Alessio Nocentini, Claudiu T. Supuran, François Bénard, Kuo-Shyan Lin
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 32, Iss 1, Pp 722-730 (2017)
Carbonic anhydrase IX (CA-IX) is a marker for tumor hypoxia, and its expression is negatively correlated with patient survival. CA-IX represents a potential target for eliminating hypoxic cancers. We synthesized fluorinated cationic sulfonamide inhib
Externí odkaz:
https://doaj.org/article/15a97448d8de47f694a70b5c4786b807
Autor:
Lin, Kelly Lu, Chengcheng Zhang, Zhengxing Zhang, Hsiou-Ting Kuo, Nadine Colpo, François Bénard, Kuo-Shyan
Publikováno v:
Molecules; Volume 28; Issue 13; Pages: 5120
Prostate-specific membrane antigen (PSMA) is a well-validated prostate cancer marker but reported PSMA-targeted tracers derived from the Lys-urea-Glu pharmacophore including the clinically validated [99mTc]Tc-EDDA/HYNIC-iPSMA have high off-target upt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=multidiscipl::58b9922355f1ffcbbca70bb056163335