Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Nadina Wand"'
Autor:
Teresa Lambe, Alexandra J. Spencer, Kelly M. Thomas, Karen E. Gooch, Stephen Thomas, Andrew D. White, Holly E. Humphries, Daniel Wright, Sandra Belij-Rammerstorfer, Nazia Thakur, Carina Conceicao, Robert Watson, Leonie Alden, Lauren Allen, Marilyn Aram, Kevin R. Bewley, Emily Brunt, Phillip Brown, Breeze E. Cavell, Rebecca Cobb, Susan A. Fotheringham, Ciaran Gilbride, Debbie J. Harris, Catherine M. K. Ho, Laura Hunter, Chelsea L. Kennard, Stephanie Leung, Vanessa Lucas, Didier Ngabo, Kathryn A. Ryan, Hannah Sharpe, Charlotte Sarfas, Laura Sibley, Gillian S. Slack, Marta Ulaszewska, Nadina Wand, Nathan R. Wiblin, Fergus V. Gleeson, Dalan Bailey, Sally Sharpe, Sue Charlton, Francisco J. Salguero, Miles W. Carroll, Sarah C. Gilbert
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-12 (2021)
Lambe, Spencer, Thomas, Gilbert and colleagues report on the detailed immune profile of rhesus macaques and ferrets vaccinated against SARS-CoV-2 under high dose challenge. Their findings indicate that the ChAdOx1 nCoV-19 (AZD1222) the vaccine induce
Externí odkaz:
https://doaj.org/article/9f8c33e0c50a4a85acb2b5617681d0f4
Autor:
Francisco J. Salguero, Andrew D. White, Gillian S. Slack, Susan A. Fotheringham, Kevin R. Bewley, Karen E. Gooch, Stephanie Longet, Holly E. Humphries, Robert J. Watson, Laura Hunter, Kathryn A. Ryan, Yper Hall, Laura Sibley, Charlotte Sarfas, Lauren Allen, Marilyn Aram, Emily Brunt, Phillip Brown, Karen R. Buttigieg, Breeze E. Cavell, Rebecca Cobb, Naomi S. Coombes, Alistair Darby, Owen Daykin-Pont, Michael J. Elmore, Isabel Garcia-Dorival, Konstantinos Gkolfinos, Kerry J. Godwin, Jade Gouriet, Rachel Halkerston, Debbie J. Harris, Thomas Hender, Catherine M. K. Ho, Chelsea L. Kennard, Daniel Knott, Stephanie Leung, Vanessa Lucas, Adam Mabbutt, Alexandra L. Morrison, Charlotte Nelson, Didier Ngabo, Jemma Paterson, Elizabeth J. Penn, Steve Pullan, Irene Taylor, Tom Tipton, Stephen Thomas, Julia A. Tree, Carrie Turner, Edith Vamos, Nadina Wand, Nathan R. Wiblin, Sue Charlton, Xiaofeng Dong, Bassam Hallis, Geoffrey Pearson, Emma L. Rayner, Andrew G. Nicholson, Simon G. Funnell, Julian A. Hiscox, Mike J. Dennis, Fergus V. Gleeson, Sally Sharpe, Miles W. Carroll
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Non-human primates are important animal models for studying SARS-CoV-2 infection. Here, Salguero et al. directly compare rhesus and cynomolgus macaques and show that both species represent COVID-19 disease of mild clinical cases, and provide a lung h
Externí odkaz:
https://doaj.org/article/87631802f4e34ba091e1f0a793783536
Autor:
Harriet N. Garlant, Kalaiarasan Ellappan, Matthew Hewitt, Prem Perumal, Simon Pekeleke, Nadina Wand, Jo Southern, Saka Vinod Kumar, Harish Belgode, Ibrahim Abubakar, Sanjeev Sinha, Seshadri Vasan, Noyal Mariya Joseph, Karen E. Kempsell
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Tuberculosis (TB) remains a significant global health crisis and the number one cause of death for an infectious disease. The health consequences in high-burden countries are significant. Barriers to TB control and eradication are in part caused by d
Externí odkaz:
https://doaj.org/article/a8fcde5172f94734be498c462b07da82
Autor:
Jake D'Addiego, Nazif Elaldi, Nadina Wand, Karen Osman, Binnur Koksal Bagci, Emma Kennedy, Ayse Nur Pektas, Eilish Hart, Gillian Slack, Roger Hewson
Publikováno v:
Journal of Medical Virology. 95
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ae0f5cdcdb194bb082a2613c2c616622
https://doi.org/10.1002/jmv.28548
https://doi.org/10.1002/jmv.28548
Autor:
Nadina Wand, Irene Taylor, Didier Ngabo, Vanessa Lucas, Rebecca Cobb, Rachel Halkerston, Susan A. Fotheringham, Stephanie Leung, Alexandra L. Morrison, Tom Tipton, Holly E. Humphries, Bassam Hallis, Phillip Brown, Kerry J Godwin, Stephen Thomas, Isabel García-Dorival, Emily Brunt, Robert J. Watson, Thomas Hender, Charlotte Nelson, Laura Hunter, Andrew White, Gillian S. Slack, Michael J. Elmore, Owen Daykin-Pont, Nathan R Wiblin, Miles W. Carroll, Breeze E. Cavell, Charlotte Sarfas, Simon G. P. Funnell, Francisco J. Salguero, Karen R. Buttigieg, Carrie Turner, Kevin R. Bewley, Jade Gouriet, Yper Hall, Marilyn Aram, Kathryn A. Ryan, Adam Mabbutt, Steve Pullan, Konstantinos Gkolfinos, Julia A. Tree, Geoffrey Pearson, Lauren Allen, Debbie J Harris, Andrew G. Nicholson, Sue Charlton, Alistair C. Darby, Naomi Coombes, Edith Vamos, Daniel Knott, Karen E. Gooch, Catherine M K Ho, Stephanie Longet, Chelsea L Kennard, Julian A. Hiscox, Xiaofeng Dong, Jemma Paterson, Mike Dennis, Emma Rayner, Fergus V. Gleeson, Elizabeth J Penn, Sally Sharpe, Laura Sibley
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
NATURE COMMUNICATIONS
Nature Communications
NATURE COMMUNICATIONS
Nature Communications
A novel coronavirus, SARS-CoV-2, has been identified as the causative agent of the current COVID-19 pandemic. Animal models, and in particular non-human primates, are essential to understand the pathogenesis of emerging diseases and to assess the saf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81382fb4483dd9827de4444c0a83e573
https://doaj.org/article/87631802f4e34ba091e1f0a793783536
https://doaj.org/article/87631802f4e34ba091e1f0a793783536
Autor:
Geoff Pearson, Marilyn Aram, Kin Chan, Rebecca A. Russell, Emma Rayner, Lauren Allen, Phillip Brown, Emily Brunt, Simon G. P. Funnell, Sally Sharpe, Debbie J Harris, Teresa Lambe, Charlotte Sarfas, Leonie Alden, Laura Sibley, Francisco J. Salguero, Andrew Gorringe, Kevin R. Bewley, Miles W. Carroll, Sue Charlton, Kathryn A. Ryan, Stephanie Longet, Chelsea L Kennard, Karen E. Gooch, Catherine M K Ho, Rebecca Cobb, Fergus V. Gleeson, Xiaochao Xue, Nathan R Wiblin, Nadina Wand, Susan A. Fotheringham, Quentin J. Sattentau, Kelly M. Thomas, Laura Hunter, Sarah C. Gilbert, Howard Tolley, Holly E. Humphries, Andrew White, Natalie Baker, Gillian S. Slack, Yper Hall, Stephanie Leung
Publikováno v:
Science Advances. 7
There is an urgent requirement for safe and effective vaccines to prevent COVID-19. A concern for the development of new viral vaccines is the potential to induce vaccine-enhanced disease (VED). This was reported in several preclinical studies with b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68fd9ab14a40593fc7510e375d4422db
https://doi.org/10.1126/sciadv.abg7996
https://doi.org/10.1126/sciadv.abg7996
Autor:
Nathan R Wiblin, Fergus V. Gleeson, Lauren Allen, Daniel B. Wright, Debbie J Harris, Leonie Alden, Teresa Lambe, Alexandra J. Spencer, Sarah C. Gilbert, Stephanie Leung, Miles W. Carroll, Kevin R. Bewley, Nadina Wand, Andrew White, Hannah Sharpe, Susan A. Fotheringham, Kathryn A. Ryan, Marta Ulaszewska, Gillian S. Slack, Carina Conceicao, Didier Ngabo, Stephen Thomas, Phillip Brown, Laura Hunter, Sue Charlton, Holly E. Humphries, Vanessa Lucas, Karen E. Gooch, Nazia Thakur, Ciaran Gilbride, Robert J. Watson, Catherine M K Ho, Emily Brunt, Rebecca Cobb, Sandra Belij-Rammerstorfer, Marilyn Aram, Breeze E. Cavell, Kelly M. Thomas, Dalan Bailey, Sally Sharpe, Laura Sibley, Charlotte Sarfas, Francisco J. Salguero, Chelsea L Kennard
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-12 (2021)
Communications Biology
Communications Biology
Vaccines against SARS-CoV-2 are urgently required, but early development of vaccines against SARS-CoV-1 resulted in enhanced disease after vaccination. Careful assessment of this phenomena is warranted for vaccine development against SARS CoV-2. Here
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33d85c7556dab6aa65b5dd213486881c
https://doi.org/10.1038/s42003-021-02443-0
https://doi.org/10.1038/s42003-021-02443-0
Autor:
Allan Bennett, Nadina Wand, Thomas Pottage, Sian Summers, David Stevenson, Christopher Burton, Ginny Moore, Kevin Richards, Linda Easterbrook, J. Dunning, James Pitman, Hannah Love, Katherine Davies, H. Rickard, Paz Aranega-Bou, Stephen R. Welch, Ant Crook, Katy-Anne Thompson, Antony Spencer
Publikováno v:
Journal of Hospital Infection
British Dental Journal
British Dental Journal
Background Understanding how severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is spread within the hospital setting is essential in order to protect staff, implement effective infection control measures, and prevent nosocomial transmissio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::feb7e9f33eca0475be8ad9771e9a6765
https://ora.ox.ac.uk/objects/uuid:62e0604f-5533-4964-ab27-b96e527db117
https://ora.ox.ac.uk/objects/uuid:62e0604f-5533-4964-ab27-b96e527db117
Autor:
Breeze E. Cavell, Marilyn Aram, Nadina Wand, Stuart D. Dowall, Susan A. Fotheringham, Daphne Tsitoura, Brendon Y. Chua, Stephen Thomas, Ian Holmes, David C. Jackson, Robert J. Watson, Pamela C. Proud, Didier Ngabo, Francesca A. Mercuri, Kevin R. Bewley, Vanessa Lucas, Kathryn A. Ryan, Gillian S. Slack, Weiguang Zeng, Christophe Demaison, Miles W. Carroll, Rebecca Cobb, Emma Rayner, Catherine M K Ho, Paul Yeates, Nathan W. Bartlett
Publikováno v:
EBioMedicine
EBioMedicine, Vol 63, Iss, Pp 103153-(2021)
EBioMedicine, Vol 63, Iss, Pp 103153-(2021)
BACKGROUND: The novel human coronavirus SARS-CoV-2 is a major ongoing global threat with huge economic burden. Like all respiratory viruses, SARS-CoV-2 initiates infection in the upper respiratory tract (URT). Infected individuals are often asymptoma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b21cacb67acae468a1e1f7b7e9cd3eae
Autor:
Sue Charlton, Julian Druce, Bassam Hallis, Robert J. Watson, Tom Tipton, Julia A. Tree, Naomi Coombes, Thomas Hender, Simon G. P. Funnell, Elizabeth J Penn, Emily Brunt, Gillian S. Slack, Kimberley Steeds, Stephanie Longet, Chelsea L Kennard, Stephanie Leung, Daniel P. Carter, Rebecca Cobb, Marilyn Aram, Breeze E. Cavell, Thomas Bean, Nathan R Wiblin, Laura Hunter, Karen L. Osman, Francisco J. Salguero, Anthony C. Marriott, Karen R. Buttigieg, Miles W. Carroll, Kevin R. Bewley, Holly E. Humphries, Kathryn A. Ryan, Phillip Brown, Kerry J Godwin, Michael G Catton, Emma Rayner, Carrie Turner, Julian A. Hiscox, Steve J. Findlay-Wilson, Nadina Wand, Yper Hall, Didier Ngabo, Rachel Halkerston, Susan A. Fotheringham, Jade Gouriet, Catherine J. Whittaker, Stephen Thomas, Irene Taylor, Mike Dennis, Karen E. Gooch, Oliver Skinner, Catherine M K Ho, Jemma Paterson, Steven T. Pullan, Lauren Allen, Debbie J Harris
Publikováno v:
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
There is a vital need for authentic COVID-19 animal models to enable the pre-clinical evaluation of candidate vaccines and therapeutics. Here we report a dose titration study of SARS-CoV-2 in the ferret model. After a high (5 × 106 pfu) and medium (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ff5e41ea44447f0a4f60a9873c2353d
http://europepmc.org/articles/PMC7782478
http://europepmc.org/articles/PMC7782478