Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Nadin Schläger"'
Autor:
Andreas Kirschning, Rolf Müller, Walid A. M. Elgaher, Rolf W. Hartmann, Mostafa M. Hamed, Sascha Baumann, Nadin Schläger, Maria Moreno, Jennifer Herrmann
Publikováno v:
Synlett. 26:1175-1178
The first total synthesis of cystobactamid 507, a member of a class of new natural products with strong inhibitory activity towards bacterial topoisomerases, is reported. Synthetic key challenges are the central tetrasubstitued arene and the low chem
Autor:
Richard Dehn, Rolf Jansen, Rolf Müller, Nadin Schläger, Andreas Kirschning, Silke Reinecke, Klaus Gerth, Heinrich Steinmetz
Publikováno v:
Angewandte Chemie. 123:553-557
Publikováno v:
Organic letters. 16(2)
The antibiotic elansolid B1 was prepared by a convergent strategy that relied on a highly diastereoselective, biomimetic intramolecular Diels–Alder cycloaddition (IMDA) that furnished the tetrahydroindane unit. Other key features are a double Sonog
Autor:
Andreas Kirschning, Nadin Schläger
Publikováno v:
Organicbiomolecular chemistry. 10(38)
The Yamamoto aldol reaction is a vinylogous aldol reaction that relies on bulky aluminium-based Lewis acids. These activate both the aldehyde as well as become part of the enolate moiety. The report discloses the first detailed study on the substrate
Publikováno v:
Organicbiomolecular chemistry. 9(7)
Ketoreductase enzymes are responsible for the generation of hydroxyl stereocentres during the biosynthesis of complex polyketide natural products. Previous studies of isolated polyketide ketoreductases have shown that the stereospecificity of ketored
Autor:
Andreas Kirschning, Richard Dehn, Silke Reinecke, Klaus Gerth, Rolf Jansen, Nadin Schläger, Heinrich Steinmetz, Rolf Müller
Publikováno v:
Angewandte Chemie (International ed. in English). 50(2)