Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Nadin, Pletz"'
Autor:
Zahra Basir Kazerouni, Daniela Hüber, Eva Maria Rieß, Anja Medack, Sigrid Hoyer-Fender, Kefei Yang, Nadin Pletz
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 1833:1338-1346
The centrosome/basal body protein ODF2/Cenexin is necessary for the formation of the primary cilium. Primary cilia are essential organelles that sense and transduce environmental signals. Primary cilia are therefore critical for embryonic and postnat
Autor:
Nadin Pletz, Matthias Dobbelstein, Karl Ziegelbauer, Steffen Emmert, Margarete Schön, Michael P. Schön, Ningshu Liu
Publikováno v:
Experimental Dermatology. 21:301-304
Drug resistance is arguably the most important challenge in cancer therapy. Here, doxorubicin induced profound of NF-κB activation in melanoma cells with a maximum (3.5-fold) at concentrations relevant in vivo. This was followed by transcriptional i
Publikováno v:
Experimental Dermatology. 21:91-98
Given that metastasized melanoma is a fatal disease in most cases, it is tempting to develop strategies to a priori prevent metastasis. We have stimulated the pulmonary innate immune system by macrophage-activating lipopeptide-2 (MALP-2), a specific
Autor:
Ningshu Liu, Karl Ziegelbauer, Margarete Schön, P. Schneider, Michael P. Schön, Steffen Emmert, Karolin Zachmann, Cornelia S. Seitz, Nadin Pletz
Publikováno v:
Experimental dermatology. 23(8)
Due to its almost universal resistance to chemotherapy, metastasized melanoma remains a major challenge in clinical oncology. Given that phosphatidyl inositol-3 kinase (PI3K) activation in melanoma cells is associated with poor prognosis, disease pro
Autor:
Nadin, Pletz, Margarete, Schön, Karl, Ziegelbauer, Steffen, Emmert, Ningshu, Liu, Matthias, Dobbelstein, Michael P, Schön
Publikováno v:
Experimental dermatology. 21(4)
Drug resistance is arguably the most important challenge in cancer therapy. Here, doxorubicin induced profound of NF-κB activation in melanoma cells with a maximum (3.5-fold) at concentrations relevant in vivo. This was followed by transcriptional i
Publikováno v:
Experimental dermatology. 21(2)
Given that metastasized melanoma is a fatal disease in most cases, it is tempting to develop strategies to a priori prevent metastasis. We have stimulated the pulmonary innate immune system by macrophage-activating lipopeptide-2 (MALP-2), a specific
Autor:
P. Schneider, Michael P. Schön, Margarete Schön, Steffen Emmert, J Glauer, Gerald Wulf, N Liu, K Ziegelbauer, Nadin Pletz
Publikováno v:
Blood Cancer Journal
Developing effective therapies against multiple myeloma (MM) is an unresolved challenge. Phosphatidylinositol-3-kinase (PI3K) activation may be associated with tumor progression and drug resistance, and inhibiting PI3K can induce apoptosis in MM cell
Autor:
Michael P. Schön, Luise Erpenbeck, Katharina Amschler, Margarete Schön, Katrin Wallbrecht, Nadin Pletz
Publikováno v:
Journal of Investigative Dermatology. (4):1073-1086
Metastasized melanoma is almost universally resistant to chemotherapy. Given that constitutive or drug-induced upregulation of NF-kappaB activity is associated with this chemoresistance, NF-kappaB inhibition may increase the susceptibility to antitum