Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Nadim Jessani"'
Autor:
Niko Bausch, Thomas Hartsch, Sebastien Ribrioux, Ludwig Macko, Nadim Jessani, Julia Retey, Asa Oudes
Publikováno v:
Industrial Biotechnology. 9:67-70
Publikováno v:
Proceedings of the National Academy of Sciences. 101:10000-10005
Metalloproteases (MPs) are a large and diverse class of enzymes implicated in numerous physiological and pathological processes, including tissue remodeling, peptide hormone processing, and cancer. MPs are tightly regulated by multiple posttranslatio
Autor:
Nadim Jessani, Benjamin F. Cravatt
Publikováno v:
Current Opinion in Chemical Biology. 8:54-59
Recent advances in genomic and proteomic technologies have begun to address the challenge of assigning molecular and cellular functions to the numerous protein products encoded by prokaryotic and eukaryotic genomes. In particular, chemical strategies
Autor:
Nadim Jessani, William Harrison Engfelt, Skaidrite K. Krisans, Janis E. Shackelford, Kim Masuda, Gilbert-Andre Keller, Vincent G. Paton, Nahla Aboushadi
Publikováno v:
Journal of Biological Chemistry. 272:24579-24587
In the liver 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase is present not only in the endoplasmic reticulum but also in the peroxisomes. However, to date no information is available regarding the function of the peroxisomal HMG-CoA reduct
Publikováno v:
Cell Cycle. 4:252-254
Human cell lines constitute powerful model systems for the in vitro and in vivo analysis of cancer. Cancer lines that are invasive in culture often form tumors and metastases in immune deficient mice. It is generally assumed that, in such cases, the
Autor:
Sherry Niessen, Mark Humphrey, Binqing Wei, Wonshik Han, Nadim Jessani, Youngran Ji, Benjamin F. Cravatt, John R. Yates, Stefanie S. Jeffrey, Monica Nicolau, Dong-Young Noh
Publikováno v:
Nature methods. 2(9)
Achieving information content of satisfactory breadth and depth remains a formidable challenge for proteomics. This problem is particularly relevant to the study of primary human specimens, such as tumor biopsies, which are heterogeneous and of finit
Autor:
Ajit Varki, Sandra Diaz, Jason A. Young, Nadim Jessani, Matthew P. Patricelli, Benjamin F. Cravatt
Publikováno v:
Angewandte Chemie (International ed. in English). 44(16)
Publikováno v:
Cell cycle (Georgetown, Tex.). 4(2)
Human cell lines constitute powerful model systems for the in vitro and in vivo analysis of cancer. Cancer lines that are invasive in culture often form tumors and metastases in immune deficient mice. It is generally assumed that, in such cases, the
Autor:
Sherry Niessen, John R. Yates, Barbara M. Mueller, Nadim Jessani, Mark Humphrey, Benjamin F. Cravatt, Kim Masuda, W. Hayes McDonald, Beena Gangadharan
Cancer research depends on the use of human cell lines for both the in vitro (culture) and in vivo (xenograft) analysis of tumor progression and treatment. However, the extent to which cultured preparations of human cancer lines display similar prope
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54ba5866d73eb187e8354dcce1c64e26
https://europepmc.org/articles/PMC518829/
https://europepmc.org/articles/PMC518829/