Molecular profiling of long‐term responders to immune checkpoint inhibitors in advanced non‐small cell lung cancer

Autor: Joan Frigola, Alejandro Navarro, Caterina Carbonell, Ana Callejo, Patricia Iranzo, Susana Cedrés, Alex Martinez‐Marti, Nuria Pardo, Nadia Saoudi‐Gonzalez, Debora Martinez, Jose Jimenez, Irene Sansano, Francesco M. Mancuso, Paolo Nuciforo, Luis M. Montuenga, Montse Sánchez‐Cespedes, Aleix Prat, Ana Vivancos, Enriqueta Felip, Ramon Amat

Publikováno v: Molecular Oncology, Vol 15, Iss 4, Pp 887-900 (2021)

Immunotherapy has transformed advanced non‐small cell lung cancer (NSCLC) treatment strategies and has led to unprecedented long‐lasting responses in some patients. However, the molecular determinants driving these long‐term responses remain el

Externí odkaz: https://doaj.org/article/5d71f89668ed4454856fe4896f4856ea

Post-surgery sequelae unrelated to disease progression and chemotherapy revealed in follow-up of patients with stage III colon cancerResearch in context

Autor: Alexia Mirandola, Andrei Kudriavtsev, Catalina Isabel Cofre Muñoz, Raquel Comas Navarro, Marco Macagno, Saidi Daoud, Cynthia Sanchez, Brice Pastor, Ekaterina Pisareva, Mireia Sanchis Marin, Javier Gonzalo Ruiz, Alejandro Piris, Ariadna Garcia Rodriguez, Nadia Saoudi Gonzalez, Ana Vivancos, Virginia Quarà, Alfredo Mellano, Felice Borghi, Giorgio Corti, Caterina Marchiò, Anna Sapino, Alice Bartolini, Giovanni Crisafulli, Alberto Bardelli, Massimo Di Maio, Gerald Lossaint, Florence Frayssinoux, Evelyne Crapez, Marc Ychou, Ramon Salazar Soler, Elisabetta Fenocchio, Paula X. Fernandez Calotti, Thibault Mazard, Cristina Santos Vivas, Elena Elez, Federica Di Nicolantonio, Alain R. Thierry

Publikováno v: EBioMedicine, Vol 108, Iss , Pp 105352- (2024)

Summary: Background: We studied the poorly-known dynamics of circulating DNA (cir-nDNA), as monitored prospectively over an extended post-surgery period, in patients with cancer. Methods: On patients with stage III colon cancer (N = 120), using perso

Externí odkaz: https://doaj.org/article/00bd9725b0694cf5a6a8cd91ec3b094f

Supplementary Data from Clinical Portrait of the SARS-CoV-2 Epidemic in European Patients with Cancer

Autor: Judith Swallow, Lorenza Scotti, Mario Pirisi, Meritxell Mollà, Maria Martinez, Luigi Mario Castello, Mattia Bellan, Gian Carlo Avanzi, Alessandra Gennari, Josep Tabernero, Aleix Prat, Armando Santoro, Michela Franchi, Alba Cabirta, Macarena Izuzquiza, Lorenzo Chiudinelli, Lorenza Rimassa, Gianluca Gaidano, Isabel Ruiz-Camps, Clara Maluquer, Anna Sureda, Javier Marco-Hernández, Daniela Ferrante, Yien Ning Sophia Wong, Rachel Sharkey, Palma Dileo, Roxana Reyes, David García-Illescas, Andrea Patriarca, Thomas Newsom-Davis, Alvin J.X. Lee, Isabel Garcia-Fructuoso, Myria Galazi, Eudald Felip, Nadia Saoudi-Gonzalez, Joanne S. Evans, Francesca D'Avanzo, Alessia Dalla Pria, Claudia Andrea Cruz, Vittoria Fotia, Salvatore Provenzano, Marta Betti, Valeria Tovazzi, Oriol Mirallas, Carlo Tondini, Neha Chopra, M. Carmen Carmona-Garcia, Rachel Wuerstlein, Andrea Marrari, Sarah Benafif, Riccardo Bruna, Anna Carbó, Diego Ottaviani, Rossella Bertulli, Bruno Vincenzi, Nadia Harbeck, Antonio Maconi, Michela Libertini, Gianpiero Rizzo, Salvatore Grisanti, Daniele Generali, Federica Biello, Elia Seguí, Ricard Mesia, Joan Brunet, Alexia Bertuzzi, Ramon Salazar, Christopher C.T. Sng, Mark Bower, Juan Aguilar-Company, Alberto Zambelli, David J. Pinato

Supplementary Tables and Figures

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c670437694eb9eb74584bdc912cb2e05
https://doi.org/10.1158/2159-8290.22536518.v1

SARS-CoV-2 omicron (B.1.1.529)-related COVID-19 sequelae in vaccinated and unvaccinated patients with cancer: results from the OnCovid registry

Autor: Alessio Cortellini, Josep Tabernero, Uma Mukherjee, Ramon Salazar, Anna Sureda, Clara Maluquer, Daniela Ferrante, Mark Bower, Rachel Sharkey, Oriol Mirallas, Andrea Plaja, Marc Cucurull, Ricard Mesia, Alessia Dalla Pria, Thomas Newsom-Davis, Mieke Van Hemelrijck, Ailsa Sita-Lumsden, Eleanor Apthorp, Bruno Vincenzi, Giuseppina Rita Di Fazio, Giuseppe Tonini, Francesco Pantano, Alexia Bertuzzi, Sabrina Rossi, Joan Brunet, Matteo Lambertini, Paolo Pedrazzoli, Federica Biello, Francesca D'Avanzo, Alvin J X Lee, Marianne Shawe-Taylor, Lucy Rogers, Cian Murphy, Lee Cooper, Ramis Andaleeb, Saira Khalique, Samira Bawany, Sarah Ahmed, M Carmen Carmona-García, Roser Fort-Culillas, Raquel Liñan, Federica Zoratto, Gianpiero Rizzo, Marta Perachino, Kris Doonga, Gianluca Gaidano, Riccardo Bruna, Andrea Patriarca, Clara Martinez-Vila, Ignacio Pérez Criado, Raffaele Giusti, Francesca Mazzoni, Lorenzo Antonuzzo, Armando Santoro, Alessandro Parisi, Paola Queirolo, Avinash Aujayeb, Lorenza Rimassa, Nikolaos Diamantis, Rossella Bertulli, Claudia A M Fulgenzi, Antonio D'Alessio, Isabel Ruiz-Camps, Nadia Saoudi-Gonzalez, David Garcia Illescas, Irene Medina, Laura Fox, Alessandra Gennari, Juan Aguilar-Company, David J Pinato, Joanne S Evans, Judith Swallow, Georgina Hanbury, Chris Chung, Meera Patel, Gino Dettorre, Katherine Belessiotis, Dolly Saorise, Eleanor Jones, Charlotte Moss, Beth Russell, Sarah Townsend, Amanda Jackson, Angela Loizidou, Martine Piccart, Fanny Pommeret, Emeline Colomba-Blameble, Aleix Prat, Claudia A Cruz, Roxana Reyes, Elia Segui, Javier Marco-Hernández, Margarita Viladot, Nadia Harbeck, Rachel Wuerstlein, Franziska Henze, Sven Mahner, Eudald Felip, Lorenza Scotti, Andrea Marrari, Federica Grosso, Vittorio Fusco, Sara Delfanti, Maura Rossi, Alberto Zambelli, Carlo Tondini, Lorenzo Chiudinelli, Michela Franchi, Michela Libertini, Salvatore Provenzano, Daniele Generali, Salvatore Grisanti, Alice Baggi, Valeria Tovazzi, Corrado Ficorella, Giampiero Porzio, Maristella Saponara, Marco Filetti, Marco Tucci, Rossana Berardi, Luca Cantini, Francesco Paoloni, Annalisa Guida, Sergio Bracarda, Maria Iglesias, Ana Sanchez de Torre, Marco Tagliamento

Background COVID-19 sequelae can affect about 15% of patients with cancer who survive the acute phase of SARS-CoV-2 infection and can substantially impair their survival and continuity of oncological care. We aimed to investigate whether previous imm

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb717c4bfe45b7df0efe50acccacef09
http://hdl.handle.net/10044/1/103056

Pharmacokinetics and pharmacodynamics of approved monoclonal antibody therapy for colorectal cancer

Autor: Nadia Saoudi Gonzalez, Daniel López, Diego Gómez, Javier Ros, Iosune Baraibar, Francesc Salva, Josep Tabernero, Elena Élez

Publikováno v: Expert opinion on drug metabolismtoxicology.

The introduction of monoclonal antibodies to the chemotherapy backbone treatment has challenged the paradigm of metastatic colorectal cancer (mCRC) treatment. Their mechanism of action and pharmacokinetics are complex but important to understand in o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7b3fd86df2d5eb031cdc3a50b9791be
https://pubmed.ncbi.nlm.nih.gov/36582117