Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Nadia S. El-Gohary"'
Autor:
Noha Hasaneen, Abdelaziz Ebead, Muhammad Murtaza Hassan, Hanan Afifi, Howard Hunter, Edward Lee-Ruff, Nadia S. El-Gohary, Azza R. Maarouf, Ali A. El-Emam
Publikováno v:
Molecules, Vol 24, Iss 18, p 3235 (2019)
The coupling of 2-bromo-3-benzoyloxycyclobutanone with purine under basic conditions produces two regioisomers consisting of the N-7 and N-9 alkylated products in equal amounts in their racemic forms. The distribution of the isomers is consistent wit
Externí odkaz:
https://doaj.org/article/4ff8ef9eff684a418eed543c88299e63
Autor:
Nayera I. Mansour, Selwan M. El-Sayed, Nadia S. El-Gohary, Naglaa I. Abdel-Aziz, Hussein I. El-Subbagh, Mariam A. Ghaly
Publikováno v:
Bioorganic Chemistry. 127:105966
A novel series of phthalimide derivatives was synthesized and evaluated for in vitro antitumor activity against six human cancer cell lines; HepG-2, HCT-116, MCF-7, Hep2, PC3 and Hela.The obtained results revealed that compound 32 was the most potent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2b9d609206f37bec6a700f3e1740580
https://doi.org/10.1016/j.bioorg.2022.105966
https://doi.org/10.1016/j.bioorg.2022.105966
Autor:
Nadia S. El-Gohary, Eman R. El-Bendary, Said M. Bayomi, Alaa A. Abd Elhameed, Mona I. Shaaban
Publikováno v:
Bioorganic Chemistry. 81:299-310
New thiazolopyrimidine and dithiazolopyrimidinone derivatives 2-11 were synthesized and estimated for antimicrobial activity against S. aureus, B. cereus, E. coli, C. albicans, A. fumigatus and A. terreus. The attained results proved that 4, 8a and 1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7348157db4591abf75f119b4305a5b7a
https://doi.org/10.1016/j.bioorg.2018.08.013
https://doi.org/10.1016/j.bioorg.2018.08.013
Publikováno v:
Bioorganicmedicinal chemistry. 28(21)
New series of isoxazole derivatives were synthesized and evaluated for in vitro antitumor activity against HepG2, MCF-7 and HCT-116 cancer cells. Results showed that 4b and 25a are the most potent members against the three cancer cells (IC50 = 6.38
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8cd0125a85178484b950998dbda297c
https://pubmed.ncbi.nlm.nih.gov/33065442
https://pubmed.ncbi.nlm.nih.gov/33065442
Publikováno v:
Bioorganic chemistry. 99
New series of 2-amino-1,4,5,6,7,8-hexahydroquinoline-3-carbonitriles 3a,b and 2-amino-5,6,7,8-tetrahydronaphthalene-1,3-dicarbonitriles 4a-h were synthesized and evaluated for their antitumor activity. In vitro antitumor screening of the new members
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da0a81f88e2647cb6adbc951cccbf7d7
https://pubmed.ncbi.nlm.nih.gov/32388203
https://pubmed.ncbi.nlm.nih.gov/32388203
Publikováno v:
Bioorganic chemistry. 102
New series of thiophene derivatives were synthesized and evaluated for their in vivo anti-inflammatory activity using carrageenan-induced paw edema model. The most active in vivo anti-inflammatory compounds 5b, 11b, 14c, 18c, 19c and 20d were further
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75e278d0ae2b63e21d8c8fbaeba5ba69
https://pubmed.ncbi.nlm.nih.gov/32801081
https://pubmed.ncbi.nlm.nih.gov/32801081
New series of pyrazolo[3,4-b]pyridines were prepared and evaluated for antimicrobial activity toward six selected microorganisms. Compounds 2a, 3b, 3d and 3e exhibited good activity toward B. cereus. On the other hand, 2a and 3b evinced interesting a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9278d5165c3ed0663e3f69edfd013345
Autor:
Saadia M. El-Ashry, Eman R. El-Bendary, Nadia S. El-Gohary, Mona I. Shaaban, Somaya A. Abdel-Rahman
Publikováno v:
European Journal of Medicinal Chemistry. 140:200-211
New series of cyclopenta(hepta)[b]thiophene and fused cyclohepta[b]thiophene analogs were synthesized. The new analogs were assessed for antibacterial efficacy toward Escherichia coli ATCC 12435, Bacillus cereus UW 85 and Staphylococcus aureus. Compo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e4396d97fd89bc870bc7d354700f528
https://doi.org/10.1016/j.ejmech.2017.08.066
https://doi.org/10.1016/j.ejmech.2017.08.066
Autor:
Nadia S. El-Gohary, Mona I. Shaaban
Publikováno v:
European Journal of Medicinal Chemistry. 137:439-449
New benzimidazole analogs were prepared and tested for antimicrobial efficacy toward Escherichia coli ATCC 12435, Bacillus cereus UW 85, Staphylococcus aureus ATCC 29213, Candida albicans and Aspergillus fumigatus 293. Results indicated that compound
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::489b06714c35f5233a6a75bbdbeb6aa7
https://doi.org/10.1016/j.ejmech.2017.05.064
https://doi.org/10.1016/j.ejmech.2017.05.064
Autor:
Edward Lee-Ruff, Muhammad Murtaza Hassan, Hanan Afifi, Azza R. Maarouf, Nadia S. El-Gohary, Howard N. Hunter, Ali A. El-Emam, Noha Hasaneen, Abdelaziz Ebead
Publikováno v:
Molecules
Volume 24
Issue 18
Molecules, Vol 24, Iss 18, p 3235 (2019)
Volume 24
Issue 18
Molecules, Vol 24, Iss 18, p 3235 (2019)
The coupling of 2-bromo-3-benzoyloxycyclobutanone with purine under basic conditions produces two regioisomers consisting of the N-7 and N-9 alkylated products in equal amounts in their racemic forms. The distribution of the isomers is consistent wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78be716ebb24697b6d27b0bd050a8c0d