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Akademický článek

Gene expression profiles of human adipose-derived mesenchymal stem cells dynamically seeded on clinically available processed nerve allografts and collagen nerve guides

Autor: Femke Mathot, Nadia Rbia, Roman Thaler, Allan B Dietz, Andre J van Wijnen, Allen T Bishop, Alexander Y Shin

Publikováno v: Neural Regeneration Research, Vol 16, Iss 8, Pp 1613-1621 (2021)

It was hypothesized that mesenchymal stem cells (MSCs) could provide necessary trophic factors when seeded onto the surfaces of commonly used nerve graft substitutes. We aimed to determine the gene expression of MSCs when influenced by Avance® Nerve

Externí odkaz: https://doaj.org/article/aa534db20b7541e2913f8f6a7c2b8a53

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Akademický článek

Gene expression and growth factor analysis in early nerve regeneration following segmental nerve defect reconstruction with a mesenchymal stromal cell-enhanced decellularized nerve allograft

Autor: Nadia Rbia, MD, Liselotte F. Bulstra, PhD, Patricia F. Friedrich, AAS, Allen T. Bishop, MD, Tim H.J. Nijhuis, MD, PhD, Alexander Y. Shin, MD

Publikováno v: Plastic and Reconstructive Surgery, Global Open, Vol 8, Iss 1, p e2579 (2020)

Background:. The purpose of this study was to evaluate the molecular mechanisms underlying nerve repair by a decellularized nerve allograft seeded with adipose-derived mesenchymal stromal cells (MSCs) and compare it to the unseeded allograft and auto

Externí odkaz: https://doaj.org/article/00edcd26abe149c08ff27ca08931183c

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Adipose derived mesenchymal stem cells seeded onto a decellularized nerve allograft enhances angiogenesis in a rat sciatic nerve defect model

Autor: Alexander Y. Shin, Allen T. Bishop, Nadia Rbia, Steven E.R. Hovius, Femke Mathot

Publikováno v: Microsurgery, 40, 585-592
Microsurgery, 40(5), 585-592. Wiley-Liss Inc.
Microsurgery, 40, 5, pp. 585-592
Microsurgery

Contains fulltext : 225110.pdf (Publisher’s version ) (Closed access) PURPOSE: Adipose derived mesenchymal stem cells (MSCs) are hypothesized to supplement tissues with growth factors essential for regeneration and neovascularization. The purpose o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::004d15b9d5de27803545001f3a076da5
https://doi.org/10.1002/micr.30579

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Collagen Nerve Conduits and Processed Nerve Allografts for the Reconstruction of Digital Nerve Gaps: A Single-Institution Case Series and Review of the Literature

Autor: Nadia Rbia, Tiam M. Saffari, Alexander Y. Shin, Steven E.R. Hovius, Liselotte F. Bulstra

Publikováno v: World Neurosurgery, 127, E1176-E1184. Elsevier Inc.

A single-institution case series is reported and a review of the literature on the outcomes of digital nerve gap reconstruction with the NeuraGen type 1 collagen nerve conduit (Integra Life Sciences, Plainsboro New Jersey, USA) and the Avance Nerve G

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fbec47eea031122605e1a3dbb9d43eb
https://doi.org/10.1016/j.wneu.2019.04.087

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Functional Outcomes of Nerve Allografts Seeded with Undifferentiated and Differentiated Mesenchymal Stem Cells in a Rat Sciatic Nerve Defect Model

Autor: Tim H.J. Nijhuis, Nadia Rbia, Tiam M. Saffari, Allen T. Bishop, Steven E.R. Hovius, Femke Mathot, Alexander Y. Shin

Publikováno v: Plastic and Reconstructive Surgery, 148, 354-365
Plast Reconstr Surg
Plastic and Reconstructive Surgery, 148, 2, pp. 354-365

Contains fulltext : 237661.pdf (Publisher’s version ) (Closed access) BACKGROUND: Mesenchymal stem cells have the potential to produce neurotrophic growth factors and establish a supportive microenvironment for neural regeneration. The purpose of t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::358b814bf64c6e7ea5fca36791267588
http://hdl.handle.net/2066/237661

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Gene expression profiles of differentiated and undifferentiated adipose derived mesenchymal stem cells dynamically seeded onto a processed nerve allograft

Autor: Nadia Rbia, Roman Thaler, Alexander Y. Shin, Andre J. van Wijnen, Allen T. Bishop, Femke Mathot

Publikováno v: Gene, 724
Gene, 724:Unsp 144151. Elsevier

Contains fulltext : 229427.pdf (Publisher’s version ) (Closed access) BACKGROUND: Differentiation of mesenchymal stem cells (MSCs) into Schwann-like cells onto processed nerve allografts may support peripheral nerve repair. The purpose of this stud

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b08ba8cddf122c855302cbf02ba85d37
https://pure.eur.nl/en/publications/3db108cc-4070-406f-b704-a9fc40474198

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Introducing human adipose-derived mesenchymal stem cells to Avance(Ⓡ) nerve grafts and NeuraGen(Ⓡ) nerve guides

Autor: Andre J. van Wijnen, Femke Mathot, Alexander Y. Shin, Allen T. Bishop, Nadia Rbia, Roman Thaler

Publikováno v: Journal of Plastic, Reconstructive and Aesthetic Surgery, 73, 8, pp. 1473-1481
Journal of Plastic, Reconstructive & Aesthetic Surgery, 73(8), 1473-1481. Churchill Livingstone
Journal of Plastic, Reconstructive and Aesthetic Surgery, 73, 1473-1481

Contains fulltext : 229446.pdf (Publisher’s version ) (Closed access) BACKGROUND: When direct nerve coaptation is impossible after peripheral nerve injury, autografts, processed allografts, or conduits are used to bridge the nerve gap. The purpose

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0777de9cd5486609dc2138c3cd475a0
https://hdl.handle.net/2066/229446

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Gene expression and growth factor analysis in early nerve regeneration following segmental nerve defect reconstruction with a mesenchymal stromal cell-enhanced decellularized nerve allograft

Autor: Allen T. Bishop, Nadia Rbia, Liselotte F. Bulstra, Patricia F. Friedrich, Alexander Y. Shin, Tim H.J. Nijhuis

Publikováno v: Plastic and Reconstructive Surgery-Global Open, 8(1):e2579. Lippincott Williams & Wilkins
Plastic and Reconstructive Surgery, Global Open, Vol 8, Iss 1, p e2579 (2020)
Plastic and Reconstructive Surgery Global Open

Supplemental Digital Content is available in the text.
Background: The purpose of this study was to evaluate the molecular mechanisms underlying nerve repair by a decellularized nerve allograft seeded with adipose-derived mesenchymal stromal cel

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6d9923fd68b0930b30280db6a4e8449
https://pure.eur.nl/en/publications/65695ae8-18a8-46ee-ae1a-12de480bb94e

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Adhesion, distribution, and migration of differentiated and undifferentiated mesenchymal stem cells (MSCs) seeded on nerve allografts

Autor: Allen T. Bishop, Alexander Y. Shin, Andre J. van Wijnen, Nadia Rbia, Femke Mathot, Steven E.R. Hovius

Publikováno v: Journal of Plastic, Reconstructive and Aesthetic Surgery, 73, 81-89
J Plast Reconstr Aesthet Surg
Journal of Plastic, Reconstructive and Aesthetic Surgery, 73, 1, pp. 81-89

Contains fulltext : 219275.pdf (Publisher’s version ) (Closed access) BACKGROUND: Although undifferentiated MSCs and MSCs differentiated into Schwann-like cells have been extensively compared in vitro and in vivo, studies on the ability and efficie

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33b76c7840ddc57353838c087de316ff
https://doi.org/10.1016/j.bjps.2019.05.030

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A Simple Dynamic Strategy to Deliver Stem Cells to Decellularized Nerve Allografts

Autor: Allen T. Bishop, Alexander Y. Shin, Andre J. Van Wijnen, Liselotte F. Bulstra, Nadia Rbia

Publikováno v: Plastic and Reconstructive Surgery, 142(2), 402-413. Lippincott Williams & Wilkins

The addition of adipose-derived mesenchymal stromal cells to decellularized nerve allografts may improve outcomes of nerve reconstruction. Prior techniques used for cell seeding are traumatic to both the mesenchymal stromal cells and nerve graft. An

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ba619cda5714088bad55e5af9bc3cee
https://hdl.handle.net/1765/114003

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