Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Nadia O. Abutaleb"'
Autor:
Nadia O. Abutaleb, Leigh Atchison, Leandro Choi, Akhil Bedapudi, Kevin Shores, Yantenew Gete, Kan Cao, George A. Truskey
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-15 (2023)
Abstract Hutchinson-Gilford Progeria Syndrome (HGPS) is a rare, fatal genetic disease that accelerates atherosclerosis. With a limited pool of HGPS patients, clinical trials face unique challenges and require reliable preclinical testing. We previous
Externí odkaz:
https://doaj.org/article/795072a3654d418481cb34a30863502b
Autor:
Leigh Atchison, Nadia O. Abutaleb, Elizabeth Snyder-Mounts, Yantenew Gete, Alim Ladha, Thomas Ribar, Kan Cao, George A. Truskey
Publikováno v:
Stem Cell Reports, Vol 14, Iss 2, Pp 325-337 (2020)
Summary: Hutchinson-Gilford progeria syndrome (HGPS) is a rare disorder caused by a point mutation in the Lamin A gene that produces the protein progerin. Progerin toxicity leads to accelerated aging and death from cardiovascular disease. To elucidat
Externí odkaz:
https://doaj.org/article/e7d2f440db154cccadc0aede2fec305b
Autor:
Nadia O. Abutaleb, George A. Truskey
Publikováno v:
STAR Protocols, Vol 2, Iss 2, Pp 100394- (2021)
Summary: Induced pluripotent stem cells (iPSCs) offer a potentially unlimited source to generate endothelial cells (ECs) for numerous applications. Here, we describe a 7-day protocol to differentiate up to 55 million vascular endothelial cells (viECs
Externí odkaz:
https://doaj.org/article/2638ed98e328420b8bc1c1817405ac60
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 8 (2021)
The vascular endothelium is present in all organs and blood vessels, facilitates the exchange of nutrients and waste throughout different organ systems in the body, and sets the tone for healthy vessel function. Mechanosensitive in nature, the endoth
Externí odkaz:
https://doaj.org/article/ee98a6ada5c548bd9ccaa84984b0d486
Publikováno v:
Methods in Molecular Biology ISBN: 9781071617076
Methods Mol Biol
Methods Mol Biol
Human tissue engineered blood vessels (TEBVs) that exhibit vasoactivity can be used to test drug toxicity, modulate pro-inflammatory cytokines, and model disease states in vitro. We developed a novel device to fabricate arteriole-scale human endothel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4841ae60cd2a394076cedbc53448f39e
https://doi.org/10.1007/978-1-0716-1708-3_7
https://doi.org/10.1007/978-1-0716-1708-3_7
Autor:
George A. Truskey, Nadia O. Abutaleb
Publikováno v:
STAR Protocols, Vol 2, Iss 2, Pp 100394-(2021)
STAR Protocols
STAR Protocols
Summary Induced pluripotent stem cells (iPSCs) offer a potentially unlimited source to generate endothelial cells (ECs) for numerous applications. Here, we describe a 7-day protocol to differentiate up to 55 million vascular endothelial cells (viECs)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::375d08a2e9f9df4dd84fdb66762da22c
http://www.sciencedirect.com/science/article/pii/S2666166721001015
http://www.sciencedirect.com/science/article/pii/S2666166721001015
Publikováno v:
Frontiers in Cardiovascular Medicine
Frontiers in Cardiovascular Medicine, Vol 8 (2021)
Frontiers in Cardiovascular Medicine, Vol 8 (2021)
The vascular endothelium is present in all organs and blood vessels, facilitates the exchange of nutrients and waste throughout different organ systems in the body, and sets the tone for healthy vessel function. Mechanosensitive in nature, the endoth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ad2ac5e3ee9b823a08028e4f06abe72
http://europepmc.org/articles/PMC7917070
http://europepmc.org/articles/PMC7917070
Autor:
Mark Juhas, Zohaib Shaikh, Nadia O. Abutaleb, Jean Ye, Nenad Bursac, Chaichontat Sriworarat, Ying Qian, Jason Wang
Publikováno v:
Nature Biomedical Engineering. 2:942-954
Adult skeletal muscle has a robust capacity for self-repair, owing to synergies between muscle satellite cells and the immune system. In vitro models of muscle self-repair would facilitate the basic understanding of muscle regeneration and the screen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c04ef9cf5c4984b06ee792cce6506925
https://doi.org/10.1038/s41551-018-0290-2
https://doi.org/10.1038/s41551-018-0290-2
Autor:
Nadia O. Abutaleb, George A. Truskey
Publikováno v:
Cell Stem Cell
Vascular smooth muscle cells (VSMCs) can be derived in large numbers from human induced pluripotent stem cells (hiPSCs) for producing tissue engineered vascular grafts (TEVGs). However, hiPSC-derived TEVGs are hampered by low mechanical strength and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0f7243b63b3187d5edd000782decd63
https://doi.org/10.1016/j.stem.2020.01.011
https://doi.org/10.1016/j.stem.2020.01.011
Autor:
Leigh Atchison, Thomas J. Ribar, Nadia O. Abutaleb, George A. Truskey, Yantenew G. Gete, Kan Cao, Alim Ladha, Elizabeth Snyder-Mounts
Publikováno v:
Stem Cell Reports
Stem Cell Reports, Vol 14, Iss 2, Pp 325-337 (2020)
Stem Cell Reports, Vol 14, Iss 2, Pp 325-337 (2020)
Summary Hutchinson-Gilford progeria syndrome (HGPS) is a rare disorder caused by a point mutation in the Lamin A gene that produces the protein progerin. Progerin toxicity leads to accelerated aging and death from cardiovascular disease. To elucidate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1bf348d3a2095ab6a1483794dde017e
https://pubmed.ncbi.nlm.nih.gov/32032552
https://pubmed.ncbi.nlm.nih.gov/32032552