Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Nadia Milech"'
Autor:
Shane R. Stone, Tatjana Heinrich, Suzy M. Juraja, Jiulia N. Satiaputra, Clinton M. Hall, Mark Anastasas, Anna D. Mills, Christopher A. Chamberlain, Scott Winslow, Kristin Priebatsch, Paula T. Cunningham, Katrin Hoffmann, Nadia Milech
Publikováno v:
Biomolecules, Vol 8, Iss 3, p 51 (2018)
The ability of cell penetrating peptides (CPPs) to deliver biologically relevant cargos into cells is becoming more important as targets in the intracellular space continue to be explored. We have developed two assays based on CPP-dependent, intracel
Externí odkaz:
https://doaj.org/article/ca42dfa2a83b4d0c880a789631e2dd6c
Autor:
Vikrant Kumar, Bryn Hardwick, Saranya Giridharan, Sneha Sudhakar, Markus Muellner, Manjunath A. Hurakadli, Ashok R. Venkitaraman, Gayathri Sadasivam, T.K. Prasad, Neelagandan Kamariah, Grahame J. McKenzie, Alex T. Crooks, Subashini Mathivanan, Paul M. Watt, Miguel Coelho, Sneha Bairy, Nadia Milech, Chandan Mithra, Christopher J. Torrance, Amy Emery, Kavitha Bharatham
Publikováno v:
Cell Chemical Biology
Summary Genetic screening technologies to identify and validate macromolecular interactions (MMIs) essential for complex pathways remain an important unmet need for systems biology and therapeutics development. Here, we use a library of peptides from
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82261f81e78bea18e12f385b6c100941
https://doi.org/10.1016/j.chembiol.2021.05.009
https://doi.org/10.1016/j.chembiol.2021.05.009
Publikováno v:
Current Opinion in Chemical Biology. 38:127-133
Phylomers are peptides derived from biodiverse protein fragments. Genetically encoded Phylomer libraries have been constructed, containing hundreds of billions of peptides derived from virtually all of the few thousand fold families found in the prot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82f2db05d4eb66ae735caa4b9da1313b
https://doi.org/10.1016/j.cbpa.2017.03.016
https://doi.org/10.1016/j.cbpa.2017.03.016
Autor:
Paula T. Cunningham, Mark Anastasas, Tatjana Heinrich, Laura Florez, Danie Champain, Theresa Connor, Paul M. Watt, Nadia Milech, Scott Winslow, Abbie M. Adams, Karen M. Kroeger, Richard W. Francis, Brooke A. C. Longville, Robert E. Dewhurst, Shane R. Stone, Yew Foon Tan, M. Scobie, Clinton M. Hall, Helena M. Viola, Maria Kerfoot, Livia C. Hool, Heique M. Bogdawa, Arne Skerra, Katrin Hoffmann, Ferrer Ong, Volker Morath, Suzy M. Juraja, Sue Fletcher, Gregory A. Weiss, Richard Hopkins
Publikováno v:
Scientific reports, vol 8, iss 1
Scientific Reports
Scientific Reports, Vol 8, Iss 1, Pp 1-16 (2018)
Scientific Reports
Scientific Reports, Vol 8, Iss 1, Pp 1-16 (2018)
Cell penetrating peptides (CPPs) offer great potential to deliver therapeutic molecules to previously inaccessible intracellular targets. However, many CPPs are inefficient and often leave their attached cargo stranded in the cell’s endosome. We re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2982281cc58305b13bc410a28e61452e
https://escholarship.org/uc/item/9539k69b
https://escholarship.org/uc/item/9539k69b
Autor:
Nadia Milech, Katrin Hoffmann, Mark Anastasas, Shane R. Stone, Suzy M. Juraja, Anna D. Mills, Christopher Aled Chamberlain, Jiulia Satiaputra, Scott Winslow, Paula T. Cunningham, Clinton M. Hall, Kristin Priebatsch, Tatjana Heinrich
Publikováno v:
Biomolecules, Vol 8, Iss 3, p 51 (2018)
Biomolecules
Volume 8
Issue 3
Biomolecules
Volume 8
Issue 3
The ability of cell penetrating peptides (CPPs) to deliver biologically relevant cargos into cells is becoming more important as targets in the intracellular space continue to be explored. We have developed two assays based on CPP-dependent, intracel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05ed2871689eb2366d186e4de44e2c55
http://www.mdpi.com/2218-273X/8/3/51
http://www.mdpi.com/2218-273X/8/3/51
Autor:
Tatjana Heinrich, Renae K. Barr, Richard W. Francis, Heique M. Bogdawa, Nadia Milech, Shane R. Stone, Robert E. Dewhurst, Paul M. Watt
Phylomers are peptides derived from fragments of proteins encoded by biodiverse genomes. Phylomer libraries were devised as a strategy to enable screening of a diverse array of peptides representing sequences that form secondary and super-secondary s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9f7cd2b256feed269730aa0148f5dbec
https://doi.org/10.1039/9781788011532-00497
https://doi.org/10.1039/9781788011532-00497
Autor:
Yew-Foon Tan, Mark Anastasas, Ferrer Ong, M. Scobie, Paul M. Watt, Tatjana Heinrich, Richard Hopkins, Maria Kerfoot, Scott Winslow, Wayne R. Thomas, Karen M. Kroeger, Nadia Milech, Paula T. Cunningham, Shane R. Stone, Brooke A. C. Longville, Theresa Connor, Katrin Hoffmann, Heique M. Bogdawa
Publikováno v:
Scientific Reports
Efficient cargo uptake is essential for cell-penetrating peptide (CPP) therapeutics, which deliver widely diverse cargoes by exploiting natural cell processes to penetrate the cell’s membranes. Yet most current CPP activity assays are hampered by l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3931f4fcfdf9f65101928a87029ea7c6
Autor:
Amanda J. Meade, Bruno P. Meloni, Paul M. Watt, Nadia Milech, Neville W. Knuckey, William R Gow, Kym Campbell
Publikováno v:
Journal of Cerebral Blood Flow & Metabolism. 31:e1-e8
In this study, we have assessed the ability of two TAT-fused peptides PYC36d-TAT and JNKI-1d-TAT (JNKI-1 or XG-102), which respectively inhibit jun proto-oncogene (c-Jun) and c-Jun N-terminal kinase (JNK) activation, to reduce infarct volume and impr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::838844a61dd88907db6f52ef0bd77160
https://doi.org/10.1038/jcbfm.2011.140
https://doi.org/10.1038/jcbfm.2011.140
Autor:
Paul M. Watt, Tanya Armstrong, A. Estcourt, C.K. Woh, Simon Reid, R. Jefferies, Anthony Armson, Rongchang Yang, Nadia Milech, T. Weldt, Richard Hopkins, Una Ryan
Publikováno v:
Experimental parasitology. 148
Cryptosporidiosis, a gastroenteric disease characterised mainly by diarrheal illnesses in humans and mammals is caused by infection with the protozoan parasite Cryptosporidium. Treatment options for cryptosporidiosis are limited, with the current the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::955ea63acd7df545075525ba7a6a008d
https://pubmed.ncbi.nlm.nih.gov/25447124
https://pubmed.ncbi.nlm.nih.gov/25447124
Publikováno v:
Genes, Chromosomes and Cancer. 32:275-280
PBX3 is a member of the PBX family of TALE homeobox genes. The prototypic member, PBX1, was first identified in chromosomal translocations in B-lineage leukemia and is required for normal hematopoiesis. PBX2 and PBX3 were later identified as members
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::318bfe1262e7f8aca388bd10e70d0cd9
https://doi.org/10.1002/gcc.1190
https://doi.org/10.1002/gcc.1190