Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Nadia Martinez Martin"'
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-12 (2022)
A high-throughput cell-based platform is developed for systematic investigation of receptor-ligand interactions and applied to identify cell-surface proteins that bind to SARS CoV-2.
Externí odkaz:
https://doaj.org/article/5dba194ff58e4aaabcc8abecee7d4c75
Autor:
Enrica Bianchi, Yi Sun, Alexandra Almansa-Ordonez, Michael Woods, David Goulding, Nadia Martinez-Martin, Gavin J. Wright
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Lack of correct embryo transport can cause ectopic pregnancy. Here, the authors show that female mice lacking the adhesion G-protein coupled receptor Adgrd1 are infertile, due to embryos being trapped in the ampulla as the result of dysregulated ovid
Externí odkaz:
https://doaj.org/article/22fbc19c7d8d408483697d387763d42a
Autor:
Jillian L. Astarita, Shilpa Keerthivasan, Bushra Husain, Yasin Şenbabaoğlu, Erik Verschueren, Sarah Gierke, Victoria C. Pham, Sean M. Peterson, Cecile Chalouni, Andrew A. Pierce, Jennie R. Lill, Lino C. Gonzalez, Nadia Martinez-Martin, Shannon J. Turley
Publikováno v:
PLoS ONE, Vol 16, Iss 12 (2021)
The cancer-associated fibroblast (CAF) marker podoplanin (PDPN) is generally correlated with poor clinical outcomes in cancer patients and thus represents a promising therapeutic target. Despite its biomedical relevance, basic aspects of PDPN biology
Externí odkaz:
https://doaj.org/article/87b716521ce444d8bffa72f85fd9fcc7
Autor:
Gareth W Fearnley, Katherine A Young, James R Edgar, Robin Antrobus, Iain M Hay, Wei-Ching Liang, Nadia Martinez-Martin, WeiYu Lin, Janet E Deane, Hayley J Sharpe
Publikováno v:
eLife, Vol 8 (2019)
Cell-cell communication in multicellular organisms depends on the dynamic and reversible phosphorylation of protein tyrosine residues. The receptor-linked protein tyrosine phosphatases (RPTPs) receive cues from the extracellular environment and are w
Externí odkaz:
https://doaj.org/article/96c8c212d7f448118d396703abc89aaa
Autor:
Nadia Martinez-Martin, Sree R. Ramani, Jason A. Hackney, Irene Tom, Bernd J. Wranik, Michelle Chan, Johnny Wu, Maciej T. Paluch, Kentaro Takeda, Philip E. Hass, Hilary Clark, Lino C. Gonzalez
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-16 (2016)
Viruses interact with their hosts via secreted and membrane-bound proteins to affect host immune responses and virulence. Here the authors contribute to our understanding of this relationship with an extracellular interaction map of human and adenovi
Externí odkaz:
https://doaj.org/article/1b4ecb9936424c34966440c431fc385a
Autor:
Nadia Martinez-Martin, Sree R. Ramani, Jason A. Hackney, Irene Tom, Bernd J. Wranik, Michelle Chan, Johnny Wu, Maciej T. Paluch, Kentaro Takeda, Philip E. Hass, Hilary Clark, Lino C. Gonzalez
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-3 (2017)
Nature Communications 7: Article number: 11473 (2016); Published: 5 May 2016; Updated: 21 August 2017 In Supplementary Fig. 3 of this Article, the sequence given for CR1B_HAdV-D19a in the alignment shown is incorrect, and should have been identical t
Externí odkaz:
https://doaj.org/article/2d3d3dc9d58a457a8a3707bac95a3833
Autor:
Nadia Martinez-Martin
Publikováno v:
Journal of Immunology Research, Vol 2017 (2017)
Pathogens have evolved unique mechanisms to breach the cell surface barrier and manipulate the host immune response to establish a productive infection. Proteins exposed to the extracellular environment, both cell surface-expressed receptors and secr
Externí odkaz:
https://doaj.org/article/b31db8fc556b4149a69699aeaee18f36
Autor:
Ariana D. Sanchez, Sean M. Peterson, Mike Reichelt, Christian M. Amador, Nadia Martinez‐Martin, Shengya Cao
Publikováno v:
Current protocolsLiterature CitedKey ReferencesInternet Resources. 2(7)
Membrane protein interactions are challenging to identify because of the unique biophysical characteristics of both transmembrane proteins and membrane environments. The Receptor Display in Membranes Interaction Screen (RDIMIS) platform overcomes the
Autor:
Marc Kschonsak, Matthew C. Johnson, Rachel Schelling, Evan M. Green, Lionel Rougé, Hoangdung Ho, Nidhi Patel, Cem Kilic, Edward Kraft, Christopher P. Arthur, Alexis L. Rohou, Laetitia Comps-Agrar, Nadia Martinez-Martin, Laurent Perez, Jian Payandeh, Claudio Ciferri
Publikováno v:
Science advances, vol. 8, no. 10, pp. eabm2536
Human cytomegalovirus (HCMV) represents the viral leading cause of congenital birth defects and uses the gH/gL/UL128-130-131A complex (Pentamer) to enter different cell types, including epithelial and endothelial cells. Upon infection, Pentamer elici
Publikováno v:
Communications biology. 5(1)
Receptor-ligand interactions on the plasma membrane regulate cellular communication and play a key role in viral infection. Despite representing main targets for drug development, the characterization of these interactions remains challenging in part