Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Nadia Maria Sposi"'
Autor:
Rosa Vona, Nadia Maria Sposi, Lorenza Mattia, Lucrezia Gambardella, Elisabetta Straface, Donatella Pietraforte
Publikováno v:
Antioxidants, Vol 10, Iss 2, p 296 (2021)
Sickle cell disease (SCD) is the most common hereditary disorder of hemoglobin (Hb), which affects approximately a million people worldwide. It is characterized by a single nucleotide substitution in the β-globin gene, leading to the production of a
Externí odkaz:
https://doaj.org/article/87abef9e2399407a831ad1d1f497bfb9
Publikováno v:
Advances in Hematology, Vol 2010 (2010)
In recent years there have been major advances in our knowledge of the regulation of iron metabolism that have had implications for understanding the pathophysiology of some human disorders like beta-thalassemia and other iron overload diseases. Howe
Externí odkaz:
https://doaj.org/article/827e4f7ef69f4123a029fe6426c7e741
Autor:
Lucrezia Gambardella, Donatella Pietraforte, Nadia Maria Sposi, Lorenza Mattia, Rosa Vona, Elisabetta Straface
Publikováno v:
Antioxidants, Vol 10, Iss 296, p 296 (2021)
Antioxidants
Antioxidants
Sickle cell disease (SCD) is the most common hereditary disorder of hemoglobin (Hb) that affects approximately a millions people worldwide. It is characterized by a single nucleotide substitution on the β-globin gene, leading to the production of ab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56fdab5e9da2b17a313ad60529e13d00
http://hdl.handle.net/11573/1557598
http://hdl.handle.net/11573/1557598
Autor:
Nadia Maria Sposi
Publikováno v:
Inherited Hemoglobin Disorders
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b7ec81702ca7129d8bde74cbb4bcc53
http://www.intechopen.com/articles/show/title/interaction-between-erythropoiesis-and-iron-metabolism-in-human-thalassemia-recent-advances-and-new-
http://www.intechopen.com/articles/show/title/interaction-between-erythropoiesis-and-iron-metabolism-in-human-thalassemia-recent-advances-and-new-
Autor:
Fabio Malavasi, Cesare Peschle, Mauro Biffoni, Ugo Testa, Gualtiero Mariani, Silvia Deaglio, Isabella Oliviero, Nadia Maria Sposi, Alessia Calzolari
Publikováno v:
Blood Cells, Molecules, and Diseases. 39:82-91
Different proteins ensure the fine control of iron metabolism at the level of various tissues. Among these proteins, it was discovered a second transferrin receptor (TfR2), that seems to play a key role in the regulation of iron homeostasis. Its muta
Autor:
Katia Fecchi, Fabio Malavasi, Cesare Peschle, Alessia Calzolari, Isabella Parolini, Carla Raggi, Silvia Deaglio, Marit Hallvardsdotter Stafsnes, Nadia Maria Sposi, Ugo Testa, Massimo Sargiacomo
Publikováno v:
Journal of Cell Science. 119:4486-4498
Transferrin receptor 2 (TfR2) possesses a YQRV motif similar to the YTRF motif of transferrin receptor 1 (TfR1) responsible for the internalization and secretion through the endosomal pathway. Raft biochemical dissection showed that TfR2 is a compone
Autor:
Ugo Testa, Nadia Maria Sposi, Eleonora Petrucci, Ernestina Saulle, Gualtiero Mariani, Marco Gabbianelli, Ornella Morsilli, Adriana Massa, Cesare Peschle
Publikováno v:
Blood. 101:2826-2832
Mechanisms underlying fetal hemoglobin (HbF) reactivation in stress erythropoiesis have not been fully elucidated. We suggested that a key role is played by kit ligand (KL). Because glucocorticoids (GCs) mediate stress erythropoiesis, we explored the
Publikováno v:
Leukemia & Lymphoma. 43:1645-1650
Interleukin 3 (IL-3), granulocyte-macrophage colony-stimulating factor (GM-CSF) and interleukin 5 (IL-5) exert their biological activities through interaction with cell-surface receptors that consist of two subunits, a specific a subunit and a common
Autor:
Cesare Peschle, Stefania Militi, T. Barberi, Elvira Pelosi, Ernestina Saulle, Elena Tritarelli, Ugo Testa, Nadia Maria Sposi, Lukas Kühn, Luciano Cianetti, Marco Gabbianelli
Publikováno v:
European Journal of Biochemistry. 267:6762-6774
We have investigated the expression of transferrin receptor (TfR) iron regulatory protein-1 (IRP-1) and iron regulatory protein-2 (IRP-2) in liquid suspension culture of purified hematopoietic progenitor cells (HPCs) induced by a growth factor stimul