Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Nadia M Ikumi"'
Publikováno v:
STAR Protocols, Vol 4, Iss 2, Pp 102276- (2023)
Summary: Fetal extravillous trophoblasts (EVTs) are the most invasive cells of the placenta and play a key role in modulating maternal immune responses. Here, we present a protocol to purify and culture human leukocyte antigen-G (HLA-G)+ EVTs. We des
Externí odkaz:
https://doaj.org/article/44922a5544a3484282e55046ddf5da39
Publikováno v:
STAR Protocols, Vol 4, Iss 2, Pp 102277- (2023)
Summary: Decidual leukocytes play key roles in maternal-fetal tolerance and immunity. Here, we present detailed methods to purify, culture, and functionally analyze human placental dNK, dTreg, dTem, and dMɸ from decidua parietalis, the maternal part
Externí odkaz:
https://doaj.org/article/b95c7c3802ac4213b82748ab59b21502
Autor:
Nadia M. Ikumi, Mushi Matjila
Publikováno v:
Frontiers in Global Women's Health, Vol 3 (2022)
Maternal HIV infection is associated with an increased risk of preterm birth (PTB). However, the mechanisms underlying this increased risk in women with HIV remain poorly understood. In this regard, it is well-established that labor is an inflammator
Externí odkaz:
https://doaj.org/article/7bc4d985894c47108cbf5f08cbce83e8
Autor:
Nadia M Ikumi, Marie-Louise Newell, Marta C. Cohen, Landon Myer, Clive M Gray, Komala Pillay, Dilly O. C. Anumba, Thokozile R Malaba, Hlengiwe P. Madlala, Mushi Matjila
Publikováno v:
AIDS. 35:717-726
OBJECTIVE To examine the association between timing of antiretroviral treatment (ART) initiation in HIV-infected women and placental histopathology. DESIGN A nested substudy in a larger cohort of HIV-infected women which examined the association betw
Autor:
Elizabeth Ann L. Enninga, Clive M. Gray, Patrick Raber, Sarah E. Kerr, Erica L Johnson, Rana Chakraborty, Reade A. Quinton, Rodrigo Ruano, Nadia M Ikumi
Publikováno v:
J Immunol
During human pregnancy, proinflammatory responses in the placenta can cause severe fetal complications, including growth restriction, preterm birth, and stillbirth. Villitis of unknown etiology (VUE), an inflammatory condition characterized by the in
Autor:
Nadia M. Ikumi, Mushi Matjila
Publikováno v:
Frontiers in global women's health. 3
Maternal HIV infection is associated with an increased risk of preterm birth (PTB). However, the mechanisms underlying this increased risk in women with HIV remain poorly understood. In this regard, it is well-established that labor is an inflammator
Publikováno v:
The Journal of antimicrobial chemotherapy. 77(2)
Dolutegravir is currently recommended by the WHO as the preferred first-line treatment for all people with HIV, including pregnant women. Estimates indicate that, by 2024, nearly 22 million adults in low- and middle-income countries will have transit
Autor:
Rana Chakraborty, Clive M. Gray, Heather B. Jaspan, Saye Khoo, Thokozile R Malaba, Komala Pillay, Nadia M Ikumi, Sonwabile Dzanibe, Mohammed Lamorde, Landon Myer, Tamara Tilburgs, Elizabeth Ann L. Enninga
Publikováno v:
J Infect Dis
Background Implementation of universal antiretroviral therapy (ART) has significantly lowered vertical transmission rates but has also increased numbers of human immunodeficiency virus (HIV)–exposed uninfected children, who remain vulnerable to mor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0a6459efa8e5c723148fbc428ce20c4
https://europepmc.org/articles/PMC8883807/
https://europepmc.org/articles/PMC8883807/
Autor:
Clive M. Gray, Heather B. Jaspan, Mohammed Lamorde, Sonwabile Dzanibe, Rana Chakraborty, Thokozile R Malaba, Tamara Tilburgs, Elizabeth Ann L. Enninga, Saye Khoo, Nadia M Ikumi, Komala Pillay, Landon Myer
BackgroundImplementation of universal antiretroviral therapy (ART) has significantly lowered vertical transmission rates but has also increased numbers of HIV-exposed uninfected children (HEU), who remain vulnerable to morbidities. Here, we investiga
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::83b9a74d7c11911f41b5c9e2b8b8e208
https://doi.org/10.1101/2021.01.04.21249198
https://doi.org/10.1101/2021.01.04.21249198
Autor:
Marie-Louise Newell, Thokozile R Malaba, Mushi Matjila, Clive M. Gray, Dilly O. C. Anumba, Hlengiwe P. Madlala, Komala Pillay, Marta C. Cohen, Nadia M Ikumi, Landon Myer
BackgroundAntiretroviral therapy (ART) is universally recommended for all HIV-infected pregnant women to improve survival and to reduce mother-to-child HIV transmission. With widespread use of ART in areas of high HIV prevalence, there is concern tha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf4fc97f0da5cdfe52ec08cc2b642294